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  • 2020-2024  (5,519)
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  • 11
    Online Resource
    Online Resource
    Pharmacoresistance in Epilepsy : From Genes and Molecules to Promising Therapies (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Neurosciences. ; Neurology . ; Pharmacology. ; Neuroscience. ; Neurology. ; Pharmacology.
    Description / Table of Contents: Chapter 1: Why study Drug Resistant Epilepsy? -- Chapter 2: Pharmacoresistance in Epilepsy -- Chapter 3: Experimental models for the study of drug-resistant epilepsy -- Chapter 4: On Complexity and Emergence: Linking the Hypotheses of Pharmacoresistance in Epilepsy -- Chapter 5: Role of High-Frequency Oscillation Networks in Managing Pharmacoresistant Epilepsy -- Chapter 6: Transporter hypothesis in pharmacoresistant epilepsies. Is it at the central or peripheral level? -- Chapter 7: Changes in Targets as an Explanation for Drug Resistance in Epilepsy -- Chapter 8: Cellular and molecular mechanisms of neuroinflammation in drug-resistant epilepsy -- Chapter 9: Contribution of the antiepileptic drug administration regime to avoid the development and/or establishment of pharmacoresistant epilepsy -- Chapter 10: Pharmacogenetics in Epilepsy and Refractory Epilepsy -- Chapter 11: Seizures Induce Hypoxia or Hypoxia Induces Seizures. A Perverse Relationship that Increases the Risk of SUDEP -- Chapter 12: Neonatal excitotoxicity triggers degenerative processes related to seizure susceptibility and pharmacoresistance -- Chapter 13: Cerebrovascular remodeling and the role of vascular endothelial growth factor in the epileptic brain and pharmacoresistance -- Chapter 14: The Role of JNK3 in Epilepsy and Neurodegeneration -- Chapter 15: Application of proteomics in the study of molecular markers in epilepsy -- Chapter 16: GABAergic neurotransmission abnormalities in pharmacoresistant epilepsy: experimental and human studies -- Chapter 17: Genes involved in pharmacoresistant epilepsy -- Chapter 18: Drug-resistant Epilepsy and the Influence of Age, Gender and Comorbid Disorders -- Chapter 19: Indications for Intracerebral Recording in Candidates for Epilepsy Surgery -- Chapter 20: On the Development of New Drugs for the Treatment of Drug Resistant Epilepsy: An Update on Different Approaches to Different Hypotheses -- Chapter 21: Physical exercise as a strategy to reduce seizure susceptibility -- Chapter 22: Ketogenic Diet and Drug-resistant Epilepsy -- Chapter 23: Modulating P-glycoprotein Regulation as a Therapeutic Strategy for Pharmacoresistant Epilepsy -- Chapter 24: Vagus Nerve Stimulation for Intractable Seizures -- Chapter 25: Non Invasive Brain Stimulation as a potential Therapeutic Procedure in drug-resistant epilepsy -- Chapter 26: Effects of transcranial focal electrical stimulation via concentric ring electrodes on seizure activity.
    Abstract: This new edition of Pharmacoresistance in Epilepsy addresses all issues relating to drug-resistance in epilepsy, including studies in patients as well in experimental models and presents the basis for an understanding of recent developments in the pathogenesis and treatment of this condition. Important issues associated with drug-resistant epilepsy are reviewed and updated, such as abnormalities in inhibitory mechanisms, neurotoxicity and changes the immune system associated with this disorder, and the development of drug-resistance as consequence of chronic exposure to antiseizure-medications. Considering that a major obstacle is that epilepsy associated with drug-resistance cannot be controlled with the traditional antiseizure medications, specific chapters describe therapeutic strategies to prevent or reduce the progression of the disease with complementary medical therapies, such as transcranial focal stimulation to promote neuroprotection. Pharmacoresistance in Epilepsy is a valuable resource for anyone working in the field, whether studying epilepsy in the lab or treating it in an office.
    Type of Medium: Online Resource
    Pages: XV, 596 p. 84 illus., 79 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031365263
    URL: https://doi.org/10.1007/978-3-031-36526-3
    DOI: 10.1007/978-3-031-36526-3
    DDC: 612.8
    Language: English
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  • 12
    Online Resource
    Online Resource
    GMOs : Implications for Biodiversity Conservation and Ecological Processes (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biodiversity. ; Conservation biology. ; Ecology . ; Biology Technique. ; Biotechnology. ; Biodiversity. ; Conservation Biology. ; Experimental Organisms. ; Biotechnology.
    Description / Table of Contents: Introduction -- Chapter 1. GMOs, Biodiversity and Ecosystem Processes Part I: GM CROPS AND THEIR IMPACTS -- Chapter 2. Impact of GM crops on farmland biodiversity -- Chapter 3. GM crops: Resistance development and impact on biodiversity -- Chapter 4. Impact of Genetically Modified Crops on the Biodiversity of Arbuscular Mycorrhizal Fungi -- Chapter 5. GMOs – Impact on Non-Target Arthropods -- Chapter 6. Impacts of Genetically Engineered Crops on the Soil Microbiome, Biological Processes and Ecosystem Services -- Chapter 7. Environmental analytical and ecotoxicological aspects of Bt maize in the Pannonian Biogeographical Region of the European Union. Part II: GM INSECTS -- Chapter 8. GM Insect biodiversity and ecological interactions -- Chapter 9. Invasive Species Control and Resolution of Wildlife Damage Conflicts: a Framework for Chemical and Genetically-based Management Methods -- Chapter 10. Risk assessment of transgenic silkworms -- Part III: GM VERTEBRATES -- Chapter 11. Genetically Engineered Fish: potential impacts on aquaculture, biodiversity, and the environment -- Chapter 12. GM Farm Animals: Potential Impact on Biodiversity Including Ethical Concerns -- Chapter 13. GM Animals: Biodiversity and Bioethical Concerns and Analysis -- Part IV: RISK ASSESSMENT -- Chapter 14. Hypothesis-led ecological risk assessment of GM crops to support decision-making about product use -- Chapter 15. Risk assessment of insect-resistant genetically modified crops on non-target arthropods and benefits to associated biodiversity of agro-ecosystems -- Chapter 16. Ecological Risk Assessment for soil invertebrate biodiversity and ecosystem services -- Part V: GENE DRIVE APPROACHES -- Chapter 17. Engineered Gene Drives: Ecological, environmental, and societal concerns -- Chapter 18. Engineered Gene Drives and their Value in the Control of Vector Borne Diseases, Weeds, Pests and Invasive Species -- Chapter 19. Evaluating Gene Drive Approaches for Public Benefit -- Part VI: GOVERNANCE AND REGULATION -- Chapter 20. Governance of Emerging Technologies/Applications in the Bio/Life Sciences: Genome Editing and Synthetic Biology -- Part VII: ANNEX A -- National legal perspectives. Africa. Chapter 21. Botswana - Genetically modified organisms (GMOs) and Synthetic biology: Their potential applications and the legal perspectives -- Chapter 22. Democratic Republic of the Congo - GMOs/synthetic biology rules/regulations and biodiversity: A legal perspective -- Chapter 23. Kenya - A Review of Regulation of Genetically Modified Organisms (GMOs) - Case Study of Kenya. Chapter 24. South Africa - Synthetic Biology Regulatory Considerations and Biodiversity: A Legal Perspective for South Africa -- Chapter 25. Tunisia - The Use of Modern Biotechnology in Tunisia: Regulatory Framework -- Chapter 26. Zimbabwe - The status of Biosafety in Zimbabwe: A legal perspective. Americas -- Chapter 27. Argentina - Regulatory Framework for Genetically Modified Organisms (GMOs) -- Chapter 28. Colombia - GMOs/innovative biotechnology regulations -- Chapter 29. Ecuador - Modern biotechnology in Ecuador: development and legal framework -- Chapter 30. Honduras - GMOs/synthetic biology rules/regulations and biodiversity: A legal perspective from Honduras -- Chapter 31. Venezuela - GMOs/regulations and biodiversity: A legal perspective in Venezuela -- Asia -- Chapter 32. India - GMOs/Synthetic Biology rules/regulations and biodiversity: A legal perspective from India -- Chapter 33. Malaysia - Genetic modifications and synthetic biology regulations and biodiversity: A legal perspective for Malaysia -- Chapter 34. Pakistan - Synthetic Biology: challenges and opportunities from a biodiversity perspective in Pakistan -- Chapter 35. Thailand - GMOs and synthetic biology regulations: Thailand perspective -- Australasia -- Chapter 36. Australia - Biodiversity Considerations as Part of the Regulation of GMOs, Including Synthetic Organisms -- Chapter 37. New Zealand - GMO Rules and Regulations in New Zealand -- Europe -- Chapter 38. Czech Republic - GMO Regulations and Biodiversity: A Legal Perspective -- Chapter 39. Hungary - Hungary’s GMO-free policy and its legal background -- Chapter 40. Italy - GMOs and synthetic biology rules/regulations and biodiversity: the legal perspective of Italy -- Chapter 41. Norway - The Norwegian Gene Technology Act: Protection of Biodiversity -- Chapter 42. Slovenia - GMOs and synthetic biology regulations and biodiversity: A Slovenian legal perspective.
    Abstract: This book covers a broad spectrum of topics related to GMOs and allied new gene-based technologies, biodiversity, and ecosystem processes, bringing together the contributions of researchers and regulators from around the world. The aim is to offer a clear view of the benefits and effects of genetically modified crops, insects, and other animals on the soil microbiome and ecological processes. Contributors examine issues related to the development of risk assessment procedures and regulations designed to maximize benefits while minimizing risks. Beyond the scientific challenges of GMOs, the book explores the broad and contentious terrain of ethical considerations. The contributors discuss such questions as the unintended, possibly unforeseen, consequences of releasing GMOs into ecosystems, and the likelihood that the full effects of GMOs could take years, even decades, of close monitoring to become evident. The importance of developing a precautionary approach is stressed. The final chapter describes the critical issues of governance and regulation of new and emerging gene-based technologies, as nations grapple with the consequences of adopting the Cartagena Protocol on Biosafety (CPB). The volume includes an extensive Annex which outlines legal perspectives on the state of GMO governance around the world, with more than 20 examples from nations in Africa, South and Central America, Asia, Australasia, and Europe. .
    Type of Medium: Online Resource
    Pages: XV, 667 p. 33 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030531836
    Series Statement: Topics in Biodiversity and Conservation, 19
    URL: https://doi.org/10.1007/978-3-030-53183-6
    DOI: 10.1007/978-3-030-53183-6
    DDC: 333.95
    Language: English
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  • 13
    Online Resource
    Online Resource
    Freshwater Red Algae : Phylogeny, Taxonomy and Biogeography (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Botany. ; Ecology . ; Water. ; Hydrology. ; Plant Science. ; Ecology. ; Water. ; Water. ; Water.
    Description / Table of Contents: History of freshwater red algae; taxonomic diversity and phylogeny; biogeographic trends; how to collect freshwater red algae; scope and organization of this book -- Subphylum Cyanidiophytina: Class Cyanidiophyceae; Subphylum Proteorhodophytina: Classes Compsopogonophyceae, Porphyridiophyceae, Rhodellophyceae and Stylonematophyceae -- Subphylum Eurhodophytina: Classes Bangiophyceae and Florideophyceae (Subclasses Corallinophycidae, Hildenbrandiophycidae and Rhodymeniophycidae) -- Subphylum Eurhodophytina: Class Florideophyceae, Subclass Nemaliophycidae, Orders Acrochaetiales, Balbianiales and Thoreales -- Subphylum Eurhodophytina: Class Florideophyceae, Subclass Nemaliophycidae, Order Batrachospermales.
    Abstract: This book presents the phylogeny, taxonomy and biogeography of freshwater red algae. Its content is divided into five chapters. The first chapter provides a brief history of freshwater red algal research, habits and collecting methods, general biogeographic trends and an overview of the taxonomic/phylogenetic placement of freshwater taxa. The other four chapters are taxonomic treatments of non-marine red algae based on taxonomic levels, i.e. classes within the phylum Rhodophyta, orders within each class, families within each order, and genera within each family. Descriptions, phylogenetic data (including numerous trees), geographic range (maps for most species) and dichotomous keys for identification are presented. Comprehensive data are provided for more than 220 species.
    Type of Medium: Online Resource
    Pages: XII, 338 p. 113 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030839703
    URL: https://doi.org/10.1007/978-3-030-83970-3
    DOI: 10.1007/978-3-030-83970-3
    DDC: 580
    Language: English
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  • 14
    Online Resource
    Online Resource
    Heat Shock Proteins of Malaria (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Parasitology. ; Proteins . ; Molecular biology. ; Cytology. ; Tropical medicine. ; Parasitology. ; Protein Biochemistry. ; Molecular Biology. ; Cell Biology. ; Tropical Medicine.
    Description / Table of Contents: Chapter 1. Introductory Chapter: The Importance of Heat Shock Proteins in Survival and Pathogenesis of the Malaria Parasite Plasmodium falciparum -- Chapter 2. General Structural and Functional Features of Molecular Chaperones -- Chapter 3. The Role of Hsp70s in the Development and Pathogenicity of Plasmodium falciparum -- Chapter 4. Role of the J Domain Protein Family in the Survival and Pathogenesis of Plasmodium falciparum. Chapter 5. Role of Hsp90 in Plasmodium falciparum Malaria -- Chapter 6. The Role of Malaria Parasite Heat Shock Proteins in Protein Trafficking and Remodelling of Red Blood Cells -- Chapter 7. Role of Heat Shock Proteins in Immune Modulation in Malaria -- Chapter 8. Bioprospecting for Novel Heat Shock Protein Modulators: The New Frontier for Antimalarial Drug Discovery? -- Chapter 9. Heat Shock Proteins as Targets for Novel Antimalarial Drug Discovery -- Chapter 10 -- Heat Shock Proteins of Malaria: Highlights and Future Prospects.
    Abstract: This new edition describes the role of heat shock proteins in the life cycle of malaria parasites, particularly in the context of intracellular parasite stages. Thoroughly revised, this work provides a general introduction to the structural and functional features of heat shock proteins with a special focus on their role as molecular chaperones in ensuring protein quality control. The emphasis is on the heat shock protein families from Plasmodium falciparum, and their role in proteostasis and the development of malaria pathology. Moreover, the authors explore the latest prospects of targeting heat shock proteins in antimalarial drug discovery either directly or in combination therapies. Readers will experience a functional analysis of the individual families of heat shock proteins and their cooperation in functional networks, including both the parasite-resident proteome and the exportome released into host cells during intracellular stages. Subcellular and extracellular organelles such as the apicoplast and the Maurer’s Clefts associated with Plasmodium species are discussed in detail. The book highlights the role of heat shock proteins in the development and function of these structures. Biochemical expertise and the inclusion of novel therapeutic solutions make this collection a unique reference for experts in heat shock protein research, parasitology and infectious diseases, cell stress, molecular biology and drug discovery. Not least, advances in malaria control will contribute to ending epidemics and ensuring healthy lives in line with the UN Sustainable Development Goals.
    Type of Medium: Online Resource
    Pages: XIII, 251 p. 26 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030783976
    Series Statement: Advances in Experimental Medicine and Biology, 1340
    URL: https://doi.org/10.1007/978-3-030-78397-6
    DOI: 10.1007/978-3-030-78397-6
    DDC: 571.999
    Language: English
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  • 15
    Online Resource
    Online Resource
    Sulfate-Reducing Bacteria and Archaea (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Microbial ecology. ; Industrial microbiology. ; Microbiology. ; Environmental Engineering/Biotechnology. ; Microbial Ecology. ; Industrial Microbiology.
    Description / Table of Contents: 1. Sulfate-reducing prokaryotes: Changing paradigms -- 2. Characteristics and taxonomy -- 3. Reduction of sulfur and nitrogen compounds -- 4. Electron transport proteins and cytochromes -- 5. Systems contributing to the energetics of SRP -- 6. Cell biology and metabolism -- 7. Geomicrobiology, biotechnology, and industrial applications -- 8. Biocorrosion -- 9. Ecology of dissimilatory sulfate reducers: Life in extreme conditions and activities of SRB -- 10. Interactions of SRB with animals and plants.
    Abstract: The abundance of sulfate-reducing bacteria and archaea (SRBA) is impressive and new isolates are being reported continuously. A few decades ago, only two genera of dissimilatory sulfate reducers had been identified and as of 2018, 92 genera containing more than 420 species of SRB and several species of archaea have been isolated. This book addresses the historical background of SRBA research and reviews the current status of research examining the growth of these anaerobic microorganisms. Additionally, this book covers metabolic and genomic diversity, enzymatic processes, response to stress, biocorrosion of ferrous metals, biogeochemical processes and interactions with other microorganisms in the anaerobic biosphere. It highlights the unique cellular and molecular features of these microorganisms, discusses the production and consumption of gases and reviews genomic content influencing their metabolic capabilities. Examples are provided of detoxification reactions to alleviate pollution situations, growth in in hostile environments including low nutrient availability, and the effects of sulfate-reducing bacteria (SRB) on human and animal hosts.
    Type of Medium: Online Resource
    Pages: XI, 564 p. 62 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030967031
    URL: https://doi.org/10.1007/978-3-030-96703-1
    DOI: 10.1007/978-3-030-96703-1
    DDC: 579
    Language: English
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  • 16
    Online Resource
    Online Resource
    Anticipatory Ethics and The Use of CRISPR in Humans (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Medical genetics. ; Biotechnology. ; Medical Genetics.
    Description / Table of Contents: Chapter 1: Brief Introduction to CRISPR Cas 9 -- Chapter 2: Introduction To Anticipatory Ethics -- Chapter 3: CRISPR, Phenomenology and Lived Experience -- Chapter 4: CRISPR and the Concept of Personhood -- Chapter 5: The use and access to CRISPR in historically socio-economically disadvantaged and marginalized communities -- Chapter 6: Future use of CRISPR: Gene Drive -- Chapter 7: Future use of CRISPR II: CRISPR Kill Switches -- Chapter 8: Domestic and International Regulation of CRISPR -- Chapter 9: Policy Recommendations with respect to CRISPR Germline Editing in Humans -- Chapter 10: Conclusions.
    Abstract: Can we move forward with the use of CRISPR in humans without a well-formed policy and ethical framework to support it? In this new book, neuroscientist Michael W. Nestor and philosopher Richard Wilson argue that the answer is a resounding “no.” Does an ethical and policy program need to be restrictive concerning the use of CRISPR in humans? Nestor and Wilson argue that, although the future of gene editing in humans is inevitable using CRISPR technologies, the scientific, policy, ethics, and clinical communities must work together to provide the necessary frameworks to help CRISPR flourish as an essential tool to treat human disease. To achieve the most inclusive, equitable, and ethically sound use of CRISPR in humans, the scientific/policy/clinical community must involve the most comprehensive set of stakeholders possible, including the lay public. This book sets a framework for shared understanding and discussion across disciplines with an appeal to scientists and non-scientists alike. The authors urge all stakeholders to engage in active dialogue about the appropriate context for using CRISPR and other gene-editing technologies in humans. It provides policy analysis and recommendations for assuring the most inclusive, equitable, and ethically sound use of CRISPR in humans, exploring its positive potential to treat mental disorders and the potential to induce other cognitive enhancements.
    Type of Medium: Online Resource
    Pages: XIX, 145 p. 13 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030983680
    URL: https://doi.org/10.1007/978-3-030-98368-0
    DOI: 10.1007/978-3-030-98368-0
    DDC: 660.6
    Language: English
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  • 17
    Online Resource
    Online Resource
    Production of Biofuels and Chemicals from Sustainable Recycling of Organic Solid Waste (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotechnology. ; Refuse and refuse disposal. ; Environmental engineering. ; Bioremediation. ; Renewable energy sources. ; Biotechnology. ; Waste Management/Waste Technology. ; Chemical Bioengineering. ; Environmental Engineering/Biotechnology. ; Renewable Energy.
    Description / Table of Contents: Part I: Introduction -- Chapter 1. Sustainable technologies for recycling organic solid wastes -- Part II: Production of Biofuels and Chemicals by Thermo-chemical Conversion Processes -- Chapter 2. Recent advances in the catalytic co-pyrolysis of lignocellulosic biomass and different polymer wastes: from laboratory scale to pilot plant -- Chapter 3. Roadmap to Low-Cost Catalytic Pyrolysis of Plastic Wastes for Production of Liquid Fuels -- Chapter 4. Production of Valuable Compounds from Leaves by Supercritical CO2 Extraction -- Part III: Production of Biofuels and Chemicals by Biodegradation -- Chapter 5. Recovery of biohydrogen and biomethane by anaerobic fermentation of organic solid waste -- Chapter 6 Recycling of multiple organic solid wastes into biogas via anaerobic digestion -- Chapter 7. Recycling of multiple organic solid wastes into chemicals via biodegradation -- Part IV Production of Liquid Biofuels with New Technologies -- Chapter 8. Producing value-added products from organic bioresources via Photo-BioCatalytic processes -- Chapter 9. Depolymerisation of fossil fuel and biomass-derived polyesters -- Chapter 10 Producing Value-added Products from Organic Solid Wastes with Mechanochemical Processes -- Chapter 11. Fundamentals of Hydrothermal Processing of Biomass-Related Molecules for Converting Organic Solid Wastes into Chemical Products -- Chapter 12 Third Generation Biorefineries Using Micro- and Macro-Algae -- Part V. Techno-Economic Analysis -- Chapter 13. Prospects and perspectives for producing biodiesel, bioethanol and bio-chemicals from fruit waste: Case study in Brazil and Serbia -- Chapter 14. Sustainable Recycling and Valorization of Organic Solid Wastes for Fuels and Fertilizers.
    Abstract: This book covers sustainable recycling processes (e.g. physical, biological, chemical, and thermo-chemical) of multiple organic solid wastes, provides methods for material recycle of wastes into value-added products including fuels and commodity chemicals that are able to be directly applied to promote manufacturing processes. Aimed at improving the awareness of effective conversion protocols and for developing innovative biomass conversion processes, this text was conceived as a collection of studies on state-of-art techniques and know-how for production of biofuels and chemicals from sustainable recycling of organic solid wastes. Topics in the text are discussed in terms of addressing recent advances, assessing and highlighting promising new methods or new technological strategies and direct conversion of organic solid wastes to process feeds. Highly-recognized authorities, experts and professionals have contributed individual chapters in selected areas to cover the overall topic in a comprehensive manner. .
    Type of Medium: Online Resource
    Pages: XVII, 506 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811661624
    Series Statement: Biofuels and Biorefineries, 11
    URL: https://doi.org/10.1007/978-981-16-6162-4
    DOI: 10.1007/978-981-16-6162-4
    DDC: 660.6
    Language: English
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  • 18
    Online Resource
    Online Resource
    Heart Valves : From Design to Clinical Implantation (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Cardiovascular system. ; Physiology. ; Biomedical engineering. ; Heart Surgery. ; Cardiology. ; Cardiovascular Physiology. ; Biomedical Engineering and Bioengineering. ; Cardiac Surgery. ; Cardiology.
    Description / Table of Contents: ANATOMY, PHYSIOLOGY, CONGENITAL DEFECTS, and DISEASE. - The anatomy and function of the atrioventricular valves -- The anatomy and function of the semilunar valves -- Congenital heart defects that include cardiac valve abnormalities -- Acquired valve disease and processes -- Complex repair of CHD requiring conduits OR valve replacement outside of the ROSS procedure -- VALVE REPAIR AND REPLACEMENT -- Heart valve disease -- History of heart valve repair -- The Ross Procedure -- The Use of Echocardiographic imaging of Valves -- Advanced 3D imaging (CT and MRI) and transcatheter valve repair/ implantation -- Transcatheter mitral repair and replacement -- Percutaneous pulmonary valve implantation: the first transcatheter valve -- Transcatheter aortic valve implantation -- Post TAVR PCI -- Complex Procedures in TAV, SAV, HARPOON, BASILICA w/ case studies -- Tissue engineered heart valves -- New trends for valve replacement like the Ozaki procedure -- Post-operative management of valves: On-X valve in post anticoagulation management -- TESTING, REGULATORY and TRAINING ISSUES -- In vitro testing of heart valve substitutes -- Numerical methods for design and evaluation of prosthetic heart valves -- Animal models for cardiac valve research -- The use of isolated heart models and anatomic specimens as means to enhance the design and testing of cardiac valve therapies -- Successful development and regulatory approval of replacement cardiac valves -- Clinical trial requirements for cardiac valves -- Virtual Prototyping and 3D Printing For Simulation -- Computational Modeling, Validation, Verification and Uncertainty: Device simulation in Valvular Anatomies -- Procedural Training and Education: Mixed Realities.
    Abstract: This state-of-the-art handbook is dedicated to cardiac valve anatomy, models for testing and research methods, clinical trials; and clinical needs and applications. In this new edition, chapters are updated with the latest research in addition to new chapters on complex repair of CHD requiring conduits, new trends for valve replacement like the Ozaki procedure, as well as complex procedures in TAV, SAV, HARPOON, and BASILICA, with case studies for each type of procedure. This volume serves as a helpful reference for patients, educators, students, device designers and developers, clinical study specialists, clinicians, and other associated healthcare providers.
    Type of Medium: Online Resource
    Pages: XVII, 615 p. 252 illus., 206 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031255410
    URL: https://doi.org/10.1007/978-3-031-25541-0
    DOI: 10.1007/978-3-031-25541-0
    DDC: 573.1
    Language: English
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  • 19
    Online Resource
    Online Resource
    Speech Perception (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: 1. The Auditory Cognitive Neuroscience of Speech Perception in Context -- 2. Subcortical Processing of Speech Sounds -- 3. Cortical Representation of Speech Sounds: Insights from Intracranial Electrophysiology -- 4. A Parsimonious Look at Neural Oscillations in Speech Perception -- 5. Extracting Language Content From Speech Sounds: The Information Theoretic Approach -- 6. Speech Perception under Adverse Listening Conditions -- 7. Adaptive Plasticity in Perceiving Speech Sounds -- 8. Development of Speech Perception -- 9. Interactions Between Audition and Cognition in Hearing Loss and Aging.
    Abstract: This volume reviews contemporary developments in the auditory cognitive neuroscience of speech perception, including both behavioral and neural contributions. It serves as an important update on the current state of research in speech perception. The Auditory Cognitive Neuroscience of Speech Perception in Context Lori L. Holt, and Jonathan E. Peelle Subcortical Processing of Speech Sounds Bharath Chandrasekaran, Rachel Tessmer, and G. Nike Gnanateja Cortical Representation of Speech Sounds: Insights from Intracranial Electrophysiology Yulia Oganian, Neal P. Fox, and Edward F. Chang A Parsimonious Look at Neural Oscillations in Speech Perception Sarah Tune, and Jonas Obleser Extracting Language Content From Speech Sounds: The Information Theoretic Approach Laura Gwilliams, and Matthew H. Davis Speech Perception under Adverse Listening Conditions Stephen C. Van Hedger, and Ingrid S. Johnsrude Adaptive Plasticity in Perceiving Speech Sounds Shruti Ullas, Milene Bonte, Elia Formisano, and Jean Vroomen Development of Speech Perception Judit Gervain Interactions Between Audition and Cognition in Hearing Loss and Aging Chad S. Rogers, and Jonathan E. Peelle .
    Type of Medium: Online Resource
    Pages: XVI, 252 p. 33 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030815424
    Series Statement: Springer Handbook of Auditory Research, 74
    URL: https://doi.org/10.1007/978-3-030-81542-4
    DOI: 10.1007/978-3-030-81542-4
    DDC: 612.8
    Language: English
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  • 20
    Online Resource
    Online Resource
    Cardiovascular Neuroendocrinology (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Neurophysiology. ; Neurons. ; Cardiovascular system. ; Physiology. ; Cardiology. ; Endocrinology. ; Cellular Neuroscience. ; Cardiovascular Physiology. ; Cardiology. ; Endocrinology.
    Description / Table of Contents: Part I. Neuroendocrine Systems and Cardiovascular Function -- Chapter 1. Neural Control of Cardiovascular Function: Role of Osmosensation -- Chapter 2. Central Neuroendocrine Control of the Cardiovascular System -- Chapter 3. Neuroendocrine Control of the Vascular System -- Chapter 4. Sex Differences in Vascular Function -- Part II. Neuroendocrinology of Cardiovascular Dysfunction and Aging -- Chapter 5. Cardiovascular Neuroendocrinology of Pregnancy -- Chapter 6. Cerebrovascular Function in Aging -- Chapter 7. Cardiovascular Responses to Exercise in Diabetes -- Chapter 8. Interactions of Stress, Psychology, and Cardiovascular Function -- Chapter 9. Neuroendocrinology Therapeutic Pathways for Cardiovascular Disease.
    Abstract: The cardiovascular system and the neuroendocrine system are integrated at multiple levels. This integration is key to normal physiological function. Further, it adapts to accommodate changes related to aging, the organism’s reproductive state, or physiological challenges. This type of adaptability, or plasticity, also can contribute to pathophysiology when these systems are stressed. This volume discusses how neuroendocrine systems influence cardiovascular function in health and disease. The first section provides detailed background information on neuronal and neuroendocrine control of cardiovascular function. This is followed by chapters highlighting the cardiovascular role of neuroendocrine hormones in regulating physiological states, such as pregnancy, and the effects of biological sex on vascular function. The influence of exercise, stress, psychology, and aging on cardiovascular function and dysfunction, and the possibility of therapeutically targeting the neuroendocrine axis for the treatment of cardiovascular disease are discussed in the final section of the book. This book is of relevance for students, trainees and established researchers alike who are seeking for an overview on the neuroendocrine control of cardiovascular function and disease. This is the fourteenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series, which aims to illustrate the highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.
    Type of Medium: Online Resource
    Pages: IX, 238 p. 27 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031399954
    Series Statement: Masterclass in Neuroendocrinology, 14
    URL: https://doi.org/10.1007/978-3-031-39995-4
    DOI: 10.1007/978-3-031-39995-4
    DDC: 612.81046
    Language: English
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