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  • 2020-2024  (3,710)
  • 1965-1969
  • 1935-1939
  • 2023  (3,710)
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  • 2020-2024  (3,710)
  • 1965-1969
  • 1935-1939
  • 2020-2023  (2)
Year
  • 1
    Online Resource
    Online Resource
    Biochemistry and Cell Biology of Ageing: Part IV, Clinical Science (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Aging. ; Cytology. ; Clinical biochemistry. ; Proteins . ; Ageing. ; Cell Biology. ; Medical Biochemistry. ; Protein Biochemistry.
    Description / Table of Contents: Chapter 1:Introduction: Historical Development and Progression of Clinical Research on Ageing -- Chapter 2:Bone Cells Metabolic Changes Induced by Ageing -- Chapter 3:Chronic Inflammation as an Underlying Mechanism of Ageing and Ageing-related Diseases -- Chapter 4: Heart Disease and Ageing: The roles of Senescence, Mitochondria and Telomerase in Cardiovascular Disease -- Chapter 5: Chronic Kidney Disease and the Exposome of Ageing -- Chapter 6: Sarcopenia and Ageing -- Chapter 7: Tendon Ageing -- Chapter 8: Virus Infections in Older People -- Chapter 9: Models and Biomarkers for Ovarian Ageing -- Chapter 10: Ageing and the Autonomic Nervous System -- Chapter 11: Astrocytes in Ageing -- Chapter 12: Hearing and Ageing -- Chapter 13: Melatonin and Ageing -- Chapter 14: Protein and Energy Supplements for the Elderly -- Chapter 15: Ageing, Metabolic Dysfunction, and the Therapeutic Role of Antioxidants -- Chapter 16: Clinical Ageing.
    Abstract: This book provides an up-to-date overview of key areas of ageing research and bridges the gap between the subcellular events and the reality of ageing as seen in clinical practice. To this end, the reader learns about the historical development and progression of clinical ageing research. All chapters address the biochemistry or cell biology of various ageing events (to the extent that the data are available) and work their way to the clinical understanding we have of ageing. The focus of this volume is on how dietary restriction, virus infection and chronic inflammation affect the ageing process. Additionally, this book discusses how phosphate metabolism and metabolic dysfunction contribute to ageing events and how various organs and tissues (e.g. tendons, ears, heart muscle, and the endocrine system) age. This book follows on from Parts I, II and III of Biochemistry and Cell Biology of Ageing within the Subcellular Biochemistry book series and aims to bring the subcellular and clinical areas into closer contact by including interesting and significant biomedical ageing topics that were not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientist alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.
    Type of Medium: Online Resource
    Pages: VIII, 458 p. 48 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031265761
    Series Statement: Subcellular Biochemistry, 103
    URL: https://doi.org/10.1007/978-3-031-26576-1
    DOI: 10.1007/978-3-031-26576-1
    DDC: 571.878
    Language: English
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  • 2
    Online Resource
    Online Resource
    Emerging Nanomaterials : Opportunities and Challenges in Forestry Sectors (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Forestry. ; Nanotechnology. ; Botany. ; Biotechnology. ; Anatomy. ; Genetics. ; Forestry. ; Nanotechnology. ; Plant Science. ; Biotechnology. ; Anatomy. ; Genetics and Genomics.
    Description / Table of Contents: Preface -- Chapter. 1. Emerging nanomaterials for forestry and associated sectors: An overview -- Chapter. 2. Potential of Nanomaterials in Bio-Based Wood Adhesives: An Overview -- Chapter. 3. Nanomaterials to improve fire properties in wood and wood-based composite panels -- Chapter. 4. Wood Plastic Composites (WPC): Applications of Nanomaterials -- Chapter. 5. Nanomaterials to improve properties in wood-based composite panels -- Chapter. 6. Nanomaterials to improve the strength of wooden joints -- Chapter. 7. Application of nanomaterials for wood protection -- Chapter. 8. Nanocellulose in paper and board coating -- Chapter. 9. Green Materials for Radiation Shielding: An overview -- Chapter. 10. Formaldehyde emissions from wood-based composites: Effects of nanomaterials.
    Abstract: Bio-based materials, including those containing wood, will become increasingly important as we move to a bio-based economy. Among their many attributes, it is vitally important that these materials are renewable, sustainable with proper management and environmentally benign. Wood remains one of our most important bio-based materials. While it is an amazing material, wood still has negative attributes and drawbacks that can affect performance, including dimensional instability when wetted, vulnerability to fire and high temperatures, and susceptibility to biodeterioration. A variety of treatments have been developed to overcome these weaknesses. Among the most exciting of these treatments are nanomaterials. These materials have some exceptionally attractive properties for improving timber performance and have been the subject of intensive research over the past decade. There is a tremendous need for a single comprehensive source of information on this rapidly emerging subject with tremendous potential to enhance the performance of a variety of bio-based materials. This book contains 10 chapters, each compiled by different author(s) who are considered the top researcher(s) in their respective fields. The chapters begin with some basic background on nanomaterials and their synthesis, then explore different areas for potential applications and conclude with a review of the emerging questions about nanomaterial safety. The book is designed to provide the latest information and know-how on application and utilization of different nanomaterials to improve the properties of wood and wood-based composite panels. The contents cover some main topics in the industry including improving physical and mechanical properties, increasing resistance to biodegradation (including fungi and insects), developing wood-plastic composites (WPC), applying nanomaterials in paper and board industry, and emergence of transparent wood and radiation shielding. It also covers the use of nanomaterials to improve the performance of paints and finishes used for forest products. The book provides a single location for those interested in the field to begin.
    Type of Medium: Online Resource
    Pages: X, 362 p. 85 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031173783
    URL: https://doi.org/10.1007/978-3-031-17378-3
    DOI: 10.1007/978-3-031-17378-3
    DDC: 634.9
    Language: English
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  • 3
    Online Resource
    Online Resource
    Microbial Genomic Islands in Adaptation and Pathogenicity (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Microbiology. ; Diseases Causes and theories of causation. ; Microbial genetics. ; Microbiology. ; Pathogenesis. ; Microbial Genetics.
    Description / Table of Contents: Chapter 1. An introduction of microbial genomic islands for evolutionary adaptation and pathogenicity -- Chapter 2. Computation tools for prediction and analysis of genomic islands -- Chapter 3. An overview of genomic islands’ main features and computational prediction: the CMNR group of bacteria as a case study -- Chapter 4. Microbial genomic island discovery, visualization and analysis -- Chapter 5. Genomic islands in bacterial genome evolution and speciation -- Chapter 6. Genomic islands in the gut microbiome: current knowledge and the application in the probiotics field -- Chapter 7. Genomic islands in nutritional fitness and adaptation -- Chapter 8. Genomic islands involved in iron uptake -- Chapter 9. Genomic islands in uropathogeneic E. coli -- Chapter 10. Genomic islands in Helicobacter species -- Chapter 11. Genomic islands in Staphylococcus -- Chapter 12. Genomic islands in Pseudomonas species -- Chapter 13. Genomic islands in Klebsiella pneumonia -- Chapter 14. Molecular Insights into Genomic Islands and Evolution of Vibrio cholerae -- Chapter 15. Genomic islands in marine bacteria -- Chapter 16. Challenges in Eventing Horizontal Gene Transfer -- chapter 17. Artificial Intelligence and machine learning for prediction and analysis of genomic islands.
    Abstract: This book elucidates the role of microbial genomic islands (GEIs) in genome stability, plasticity, evolutionary adaptation, and pathogenicity in the bacterial population. The initial chapters of the book present tools, including bioinformatics, artificial intelligence, machine learning, next-generation sequencing, and molecular biology techniques, for the analysis of the genomic islands. The book also discusses the importance of genomic islands in bacterial speciation, acquisition of genes related to resistome, nitrogen fixation, mobilomes, and nutritional fitness and adaptation. It provides recent advances in understanding microbial genomic islands' distribution, evolution, and mechanistic modes of behavior in pathogenic, non-pathogenic, and environmental species. This book is a valuable source for beginners in molecular microbiology, students, researchers, clinicians, stakeholders, and policymakers interested in understanding the role of GEIs in the adaptive evolution of microorganisms.
    Type of Medium: Online Resource
    Pages: XXIII, 356 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811993428
    URL: https://doi.org/10.1007/978-981-19-9342-8
    DOI: 10.1007/978-981-19-9342-8
    DDC: 579
    Language: English
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  • 4
    Online Resource
    Online Resource
    Circulating Tumor Cells : Advances in Liquid Biopsy Technologies (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cancer Treatment. ; Tumor markers. ; Cancer Biology. ; Cancer Therapy. ; Tumour Biomarkers.
    Description / Table of Contents: Part 1. CTC Technologies -- Affinity -- Physical -- ctDNA -- miRNA -- Exosomes -- Part 2 -- Biology of CTC -- Dormancy -- Culture -- EMT -- ctDNA and Exosomes -- Cells in circulation with CTC -- Part 3 -- CTC Analysis -- IHC, FISH, and other molecular assays -- Functional characterization -- Advanced microscopy and AI -- Analysis of non-cellular circulating markers -- Part 4 -- Clinical Applications of the Liquid Biopsy -- Early detection and cancer screening -- Prognosis and therapeutic monitoring -- Applications in Clinical Trials -- Applications in Drug Development.
    Abstract: It is well recognized that blood could be the optimal site for evaluating cancer, allowing easy and repeated access for determining prognosis, establishing molecular targets, evaluating the efficacy of therapy, detecting the earliest signs of recurrence, and even detecting cancer at its earliest and most curable stages. The analysis of cancer through blood samples is now known as the liquid biopsy and has been a rich source of research and clinical application. There has been an explosion of interest and progress in liquid biopsy technologies since the first edition of this book. The second edition will expand its focus to now include not only circulating tumor cells (CTC), but also other emerging aspects of the liquid biopsy, including circulating tumor DNA and methylated DNA (ctDNA, ct meDNA), ctRNA, ct miRNA, circulating tumor proteins (and other) biomarkers and circulating tumor derived exosomes (ctExosomes).
    Type of Medium: Online Resource
    Pages: XXI, 668 p. 77 illus., 72 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031229039
    Series Statement: Current Cancer Research,
    URL: https://doi.org/10.1007/978-3-031-22903-9
    DOI: 10.1007/978-3-031-22903-9
    DDC: 571.978
    Language: English
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  • 5
    Online Resource
    Online Resource
    Visceral Pain (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Neurosciences. ; Neurophysiology. ; Gastroenterology. ; Neuroscience. ; Neurophysiology. ; Gastroenterology.
    Description / Table of Contents: Tools for optogenetic probing of nociceptive pathways; Monitoring activity -- An open science model to accelerate the generation, implementation and distribution of optogenetics and viral tools -- Vagal neuroinflammation accompanying respiratory viral infection: An overview of mechanisms and possible clinical significance -- Stress-induced Visceral Analgesia: Concept and Pathways -- Evidence of early life stress exposure and epigenetic modifications in functional chronic pain disorders -- EPIGENETIC REGULATION OF STRESS-INDUCED VISCERAL PAIN -- The biomechanics and mechanotransduction in visceral nociception -- VISCERAL NOCICEPTION IN GASTROINTESTINAL DISEASE -- Epithelial-Neuronal Communication in Visceral Pain -- Physiological Mechanisms Underpinning Heightened Perception of Visceral Afferent Signalling in Irritable Bowel Syndrome -- A fentanyl analogue that activates u-opioid receptors in acidified tissues inhibits colitis pain without opioid side effects -- Signalling in the Gut -- Translating colonic sensory afferent peripheral mechanosensitivity into the spinal cord dorsal horn -- Translating colonic afferent peripheral sensitivity into the spinal cord dorsal horn -- Neuron-Microglia Dynamic Duo in Chronic Abdominal Pain -- Pre-clinical Models of Endometriosis -- Spinal afferent innervation of the uterus -- Post-infectious bladder hypersensitivity in the development of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).
    Abstract: The chapters in this book are based on the Visceral Pain conference in Adelaide, Australia, under the auspices of the International Federation for Neurogastroenterology and Motility in 2021. This is one of the hottest fields of science and includes mechanisms involving how the microbiome communicates with the brain and how, when disordered, these mechanisms contribute to clinical diseases such as Irritable Bowel Syndrome and Inflammatory Bowel Disease. Researchers from around the globe presented their latest findings as a review of the current state of the art in the field from both the clinical and scientific points of view. These systems are now appreciated as being critical for shaping our well-being and their disorders underlie chronic clinical conditions of significant morbidity and mortality. The author team includes long-established authorities who significantly contributed to the advances in visceral pain research over the past two decades and the new generation that will continue to contribute to advancing our understanding of the field.
    Type of Medium: Online Resource
    Pages: VIII, 255 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031257025
    URL: https://doi.org/10.1007/978-3-031-25702-5
    DOI: 10.1007/978-3-031-25702-5
    DDC: 612.8
    Language: English
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  • 6
    Online Resource
    Online Resource
    Modern Survival Analysis in Clinical Research : Cox Regressions Versus Accelerated Failure Time Models (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Medical sciences. ; Statistics . ; Health Sciences. ; Applied Statistics.
    Description / Table of Contents: Preface -- Chapter 1: Regression Analysis -- Chapter 2: Cox Regressions -- Chapter 3: Accelerated Failure Time Models -- Chapter 4: Simple Dataset with Event as Outcome and Treatment as Predictor -- Chapter 5: Simple Dataset with Death as Outcome and Treatment Modality, Cholesterol, and Age as Predictors -- Chapter 6: Glioma Brain Cancer -- Chapter 7: Linoleic Acid for Colonic Carcinoma -- Chapter 8: The Effect on Survival of Maintained Chemotherapy with Acute Myelogenous Leucemia -- Chapter 9: Eighty Four Month Parallel Group Mortality Study -- Chapter 10: The Effect on Survival from Stages 1 and 2 Histiocytic Lymphoma -- Chapter 11: Survival of 64 Lymphoma Patients with or without B Symptoms -- Chapter 12: Effect on Time-to-Event of Group Membership -- Chapter 13: The Effect on Survival of Group Membership -- Chapter 14: Deaths from Carcinoma after Exposure to Carcinogens in Rats -- Chapter 15: Effect of Group Membership on Survival -- Chapter 16: Multiple Variables Regression Study of 2421 Stroke Patients Assessed for Time to Second Stroke -- Chapter 17: Hypothesized 55 Patient Study of Effect of Treatment Modality on Survival -- Chapter 18: One Year Follow-up Study with Many Censored Patients -- Chapter 19: Alcohol Relapse after Detox Program Treated with or without Personal Coach -- Chapter 20: Alcohol Relapse after Detox Program with 3 Predictors -- Chapter 21: Ayurvedic Therapy for Human Immunodeficiency Virus -- Chapter 22: Time to Event other Than Cox -- Chapter 23: Abstracts of the Chapters 1 to 22.
    Abstract: An important novel menu for Survival Analysis entitled Accelerated Failure Time (AFT) models has been published by IBM (international Businesss Machines) in its SPSS statistical software update of 2023. Unlike the traditional Cox regressions that work with hazards, which are the ratio of deaths and non-deaths in a sample, it works with risk of death, which is the proportion of deaths in the same sample. The latter approach may provide better sensitivity of testing, but has been seldom applied, because with computers risks are tricky and hazards because they are odds are fine. This was underscored in 1997 by Keiding and colleague statisticians from Copenhagen University who showed better-sensitive goodness of fit and null-hypothesis tests with AFT than with Cox survival tests. So far, a controlled study of a representative sample of clinical Kaplan Meier assessments, where the sensitivity of Cox regression is systematically tested against that of AFT modeling, has not been accomplished. This edition is the first textbook and tutorial of AFT modeling both for medical and healthcare students and for professionals. Each chapter can be studied as a standalone, and, using, real as well as hypothesized data, it tests the performance of the novel methodology against traditional Cox regressions. Step by step analyses of over 20 data files stored at Supplementary Files at Springer Interlink are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology (2000-2002). From their expertise they should be able to make adequate selections of modern data analysis methods for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 25 years and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.
    Type of Medium: Online Resource
    Pages: XIV, 224 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031316326
    URL: https://doi.org/10.1007/978-3-031-31632-6
    DOI: 10.1007/978-3-031-31632-6
    DDC: 610
    Language: English
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  • 7
    Online Resource
    Online Resource
    Imaging Inflammation (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Radiology. ; Pathology. ; Immunology. ; Radiology. ; Pathology. ; Immunology.
    Description / Table of Contents: Chapter 1. Imaging Inflammation: A Historical Perspective -- Chapter 2. Nuclear Imaging of Inflammation -- Chapter 3. Magnetic Resonance Imaging of Inflammation -- Chapter 4. Ultrasound Imaging in Inflammation Research -- Chapter 5. Whole-body Chemiluminescence and Fluorescence Imaging of Inflammation -- Chapter 6. Photoacoustic Imaging in Inflammation Research -- Chapter 7. Imaging Inflammation by Intravital Microscopy -- Chapter 8. Spatial Transcriptomics in Inflammation: Dissecting the Immune Response in 3D in Complex Tissues.
    Abstract: Imaging Inflammation provides updates on cutting-edge imaging methods being applied to problems in inflammation research. From state-of-the-art research tools to diagnostic tests, and from single-cell to whole-body imaging, this volume offers a comprehensive overview of how imaging experts across a range of disciplines are expanding our understanding of inflammation and immunity.
    Type of Medium: Online Resource
    Pages: XV, 279 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031236617
    Series Statement: Progress in Inflammation Research, 91
    URL: https://doi.org/10.1007/978-3-031-23661-7
    DOI: 10.1007/978-3-031-23661-7
    DDC: 616.0757
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cardiovascular Neuroendocrinology (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Neurophysiology. ; Neurons. ; Cardiovascular system. ; Physiology. ; Cardiology. ; Endocrinology. ; Cellular Neuroscience. ; Cardiovascular Physiology. ; Cardiology. ; Endocrinology.
    Description / Table of Contents: Part I. Neuroendocrine Systems and Cardiovascular Function -- Chapter 1. Neural Control of Cardiovascular Function: Role of Osmosensation -- Chapter 2. Central Neuroendocrine Control of the Cardiovascular System -- Chapter 3. Neuroendocrine Control of the Vascular System -- Chapter 4. Sex Differences in Vascular Function -- Part II. Neuroendocrinology of Cardiovascular Dysfunction and Aging -- Chapter 5. Cardiovascular Neuroendocrinology of Pregnancy -- Chapter 6. Cerebrovascular Function in Aging -- Chapter 7. Cardiovascular Responses to Exercise in Diabetes -- Chapter 8. Interactions of Stress, Psychology, and Cardiovascular Function -- Chapter 9. Neuroendocrinology Therapeutic Pathways for Cardiovascular Disease.
    Abstract: The cardiovascular system and the neuroendocrine system are integrated at multiple levels. This integration is key to normal physiological function. Further, it adapts to accommodate changes related to aging, the organism’s reproductive state, or physiological challenges. This type of adaptability, or plasticity, also can contribute to pathophysiology when these systems are stressed. This volume discusses how neuroendocrine systems influence cardiovascular function in health and disease. The first section provides detailed background information on neuronal and neuroendocrine control of cardiovascular function. This is followed by chapters highlighting the cardiovascular role of neuroendocrine hormones in regulating physiological states, such as pregnancy, and the effects of biological sex on vascular function. The influence of exercise, stress, psychology, and aging on cardiovascular function and dysfunction, and the possibility of therapeutically targeting the neuroendocrine axis for the treatment of cardiovascular disease are discussed in the final section of the book. This book is of relevance for students, trainees and established researchers alike who are seeking for an overview on the neuroendocrine control of cardiovascular function and disease. This is the fourteenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series, which aims to illustrate the highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.
    Type of Medium: Online Resource
    Pages: IX, 238 p. 27 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031399954
    Series Statement: Masterclass in Neuroendocrinology, 14
    URL: https://doi.org/10.1007/978-3-031-39995-4
    DOI: 10.1007/978-3-031-39995-4
    DDC: 612.81046
    Language: English
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  • 9
    Online Resource
    Online Resource
    Polystomatid Flatworms : State of Knowledge and Future Trends (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Parasitology. ; Veterinary medicine. ; Zoology. ; Ecology . ; Evolution (Biology). ; Parasitology. ; Veterinary Science. ; Zoology. ; Ecology. ; Evolutionary Biology.
    Description / Table of Contents: Chapter 1. Overview of the Polystomatidae: Systematics and Classification -- Chapter 2. Contributions to the History of Polystomatid Flatworm Discoveries and Research -- Chapter 3. Collecting and Processing Polystomatid Flatworms -- Chapter 4. Polystome Species of Amphibians -- Chapter 5. Polystome Species of the Australian Lungfish, Chelonians and the Common Hippopotamus -- Chapter 6. Polystomatidae: Life-History Strategies, the Key to Success -- Chapter 7. Insights into the Origin and Evolution of the Polystomatidae -- Chapter 8. Poystomatid Studies: Future Prospects.
    Abstract: This unique book offers a comprehensive guide to the fascinating world of polystomatid flatworms. It introduces the reader to the individual life histories of polystomes and the chronological advances in our knowledge, with descriptions of species discovered over the past centuries. It equips newcomers to the field with basic protocols and techniques for collecting, processing and interpreting material. It also presents the history of research on this group of parasites, provides information on the discovery of each polystome and acknowledges the authors that have made major contributions. For the established researcher in the field, it offers a reference book containing taxonomic data, measurements and drawings of all known polystomes. The authors have brought together all the available material, creating a resource that will stimulate research and revive the global focus on this unique group of parasites. Thus, this work provides an essential reference for both established researchers and newcomers to the field.
    Type of Medium: Online Resource
    Pages: XVII, 645 p. 250 illus., 246 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031358876
    Series Statement: Zoological Monographs, 9
    URL: https://doi.org/10.1007/978-3-031-35887-6
    DOI: 10.1007/978-3-031-35887-6
    DDC: 571.999
    Language: English
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  • 10
    Online Resource
    Online Resource
    Virus Infected Cells (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Virology. ; Clinical biochemistry. ; Diseases Causes and theories of causation. ; Microbiology. ; Molecular biology. ; Biology Technique. ; Virology. ; Medical Biochemistry. ; Pathogenesis. ; Microbiology. ; Molecular Biology. ; Biological Techniques.
    Description / Table of Contents: Part 1: General / Technical Aspects -- Chapter 1: In Situ Imaging Of Virus Infected Cells By Cryo-Electron Tomography: An Overview -- Chapter 2: Approaches To Evaluating Necroptosis In Virus Infected Cells -- Chapter 3: Apoptosis And Phagocytosis As Antiviral Mechanisms -- Chapter 4: The Art Of Viral Membrane Fusion And Penetration -- Chapter 5: Single Particle Tracking Of Virus Entry In Live Cells -- Chapter 6: Correlative Cryo-Imaging Using Soft X-Ray Tomography For The Study Of Virus Biology In Cells And Tissues -- Chapter 7: The Virus-Induced Cytopathic Effect -- Part 2: Specific Viruses -- Chapter 8: Human Papilloma Virus-Infected Cells -- Chapter 9: Defining The Assembleome Of The Respiratory Syncytial Virus -- Chapter 10: Japanese Encephalitis Virus Infected Cells -- Chapter 11: African Swine Fever Virus Host-Pathogen Interactions -- Chapter 12: Coronavirus And The Cytoskeleton Of Virus-Infected Cells -- Chapter 13: Viral Rna Is A Hub For Critical Host-Virus Interactions -- Chapter 14: Influenza A Virus: Cellular Entry -- Chapter 15: Human Endogenous Retroviruses In Diseases -- Chapter 16: Cholesterol And M2 Rendezvous In Budding And Scission Of Influenza A Virus.
    Abstract: Virus-infected Cells is a comprehensive and technical exploration of the intricate interactions between viruses and host cells. This book delves into the molecular and cellular aspects of viral infections, providing a wealth of knowledge about various viruses and their effects on cellular mechanisms. The first part of the book covers general/technical aspects, introducing the reader to the field of virology and providing an overview of the techniques used to study virus-infected cells. It covers topics such as the visualisation of virus-infected cells by cryo-electron tomography and the assessment of necroptosis, a type of programmed cell death, in virus-infected cells. In addition, the book explores the role of apoptosis and phagocytosis as antiviral mechanisms, as well as the intricate process of viral membrane fusion and penetration. It also discusses the tracking of viral entry into living cells and the use of correlative cryo-imaging to study the biology of viruses in cells and tissues. Finally, the book examines the cytopathic effect induced by viruses, shedding light on the damage caused to infected cells. The second section of the book explores specific viruses and their interactions with host cells. Each chapter focuses on a specific virus and provides an in-depth look at its behaviour within infected cells. The book covers a wide range of viruses, including human papillomavirus, respiratory syncytial virus, Japanese encephalitis virus, African swine fever virus, coronavirus, influenza A virus and human endogenous retroviruses. Each chapter examines unique aspects of virus-host interactions, such as viral assembly, impact on the cytoskeleton, critical host-virus interactions mediated by viral RNA, mechanisms of cell entry, and the involvement of cholesterol in virus budding and scission. This volume in the Subcellular Biochemistry series is a valuable resource for researchers, virologists and students interested in understanding the complex dynamics between viruses and the cells they infect. With its detailed exploration of general and specific aspects of virus-host interactions, this book provides a comprehensive understanding of the molecular and cellular mechanisms involved in viral infections.
    Type of Medium: Online Resource
    Pages: VIII, 459 p. 70 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031400865
    Series Statement: Subcellular Biochemistry, 106
    URL: https://doi.org/10.1007/978-3-031-40086-5
    DOI: 10.1007/978-3-031-40086-5
    DDC: 579.2
    Language: English
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