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  • 1
    Keywords: Evolution (Biology). ; Environment. ; History. ; Conservation biology. ; Ecology . ; Ethics. ; Environmental sciences Social aspects. ; Evolutionary Biology. ; Environmental Sciences. ; History. ; Conservation Biology. ; Moral Philosophy and Applied Ethics. ; Environmental Social Sciences.
    Description / Table of Contents: Part I. Biology and Culture -- Chapter 1. Speciesism in Biology and Culture: How Human Exceptionalism is Pushing Planetary Boundaries -- Chapter 2. Race and Human Genomic Variation -- Chapter 3. Science Without Species: Doing Science With Tree-Thinking -- Part II. Culture and History -- Chapter 4. The Colonization of Islands as Microcosms for Human Impacts on an Interplanetary Scale -- Chapter 5. Species, God, and Dominion -- Chapter 6. Symbols and How We Came to be Human -- Part III. Conservation and Law -- Chapter 7. Law and Nature: Human, Nonhuman, and Ecosystem Rights -- Chapter 8. A Phylogenetic Approach to Conservation: Biodiversity and Ecosystem Functioning for a Changing Globe -- Part IV. Sustainability and the Future -- Chapter 9. Energy and Society: Toward a Sustainable Future.
    Abstract: This open access book explores a wide-ranging discussion about the sociopolitical, cultural, and scientific ramifications of speciesism and world views that derive from it. In this light, it integrates subjects across the natural sciences, social sciences, and humanities. The 21st-century western world is anthropocentric to an extreme; we adopt unreasonably self-centered and self-serving ideas and lifestyles. Americans consume more energy resources per person than most other nations on Earth and have little concept of how human ecology and population biology interface with global sustainability. We draw upon religion, popular culture, politics, and technology to justify our views and actions, yet remain self-centered because our considerations rarely extend beyond our immediate interests. Stepping upward on the hierarchy from “racism,” “speciesism” likewise refers to the view that unique natural kinds (species) exist and are an important structural element of biodiversity. This ideology manifests in the cultural idea that humans are distinct from and intrinsically superior to other forms of life. It further carries a plurality of implications for how we perceive ourselves in relation to nature, how we view Judeo-Christian religions and their tenets, how we respond to scientific data about social problems such as climate change, and how willing we are to change our actions in the face of evidence. .
    Type of Medium: Online Resource
    Pages: XVI, 203 p. 28 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030990312
    DDC: 576.8
    Language: English
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  • 2
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Geography. ; Environment. ; Power resources. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Regional Geography. ; Environmental Sciences. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Intro: Navigating Patagonian freshwaters- and this book -- 1: Are freshwaters wetlands? -- 2: Patagonian Andean lakes and climate change -- 3: Current state and recent changes of glaciers in the Patagonian Andes (35 °S to 55°S) -- 4: Biogeographical patterns of Patagonian freshwater microbiota -- 5: Extreme freshwater ecosystems from Patagonia: The Copahue-Agrio system -- 6: Mercury in aquatic systems of North Patagonia: sources, processes and trophic transfer -- 7: Diversity patterns across aquatic communities from peat bogs -- 8: Hydrologic Systems, water uses and emerging conflicts around freshwater availability in Patagonia -- 9: Land-use effects on aquatic ecosystems: An overview of environmental impacts and tools for ecological assessment -- 10: Patagonian wetlands: vertientes, vegas, mallines,turberas and lagunas -- 11: Fish and fisheries of the Patagonian steppe -- 12: Invasive species: The case of Didymosphenia geminata in Neuquén Province -- 13: Influence of the fish introduction in lakes of the arid Patagonia -- 14: Patagonian cultural limnology: knowledge and water management in Mapuche rural communities -- 15: Political Ecology, water valoration and Water Law deliberation in the Province of Tierra del Nacional de Tierra del Fuego -- 16: Freshwater systems in protected areas in Patagonia -- 17: Amphibians and waterbirds as bridges to conserve aquatic and terrestrial habitat in Patagonia -- 18: Integrated long term conservation strategies to recover the critically endangered Hooded Grebe (Podiceps gallardoi),an endemic waterbird of Austral Patagonia -- Conclusion: Reaching out for the UNDP Sustainable Development Goals in Patagonia.
    Abstract: The Freshwaters of Patagonia adopts a socioecological approach, in which experts from across Patagonia review recent, scientifically rigorous literature and data of their own, thus synthesizing the current knowledge directly relevant to understand the present state and future trends of icefields, freshwater and wetland ecosystems in this region. The book’s organization into three parts provides a studied and comprehensive view on the patterns and processes of the various ecosystems in Patagonia, and describes the sociological aspects of freshwater ecosystems, as well as characterizes the conservation of the freshwater and wetland ecosystems, in Patagonia. The chapters offer a broad, state-of-the-art overview of the current status of glaciers, freshwater and wetland ecosystems of this region, as well as studies of both local and large scale biodiversity patterns, and study cases of extreme and naturally polluted environments.The volume concludes with the current status of Patagonian freshwaters, and discusses the scientific, legal and administrative tools aimed at their sustainable management within the framework of the UNEP Sustainable Development Goals 2030 Agenda. A broad audience of students, scientists, engineers, environmental managers, and policy makers will be interested in this volume.
    Type of Medium: Online Resource
    Pages: XI, 541 p. 104 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031100277
    Series Statement: Natural and Social Sciences of Patagonia,
    DDC: 577.6
    Language: English
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  • 3
    Keywords: Medical sciences. ; Radiology. ; Neurology . ; Health Sciences. ; Radiology. ; Neurology.
    Description / Table of Contents: The subcortical space: anatomy of the subcortical white matter -- Common pathology of the subcortical region -- The ventricular system: Anatomy and common lesions -- Advanced neuro-imaging of the subcortical space -- Advanced neuro-imaging of the human ventricular system -- The evolution of trans-sulcal, channel-based parafascicular surgery -- Open transcortical approaches to subcortical lesions -- Traditional open and neuro-endoscopic approaches to intraventricular pathology -- Trans-sulcal, channel-based parafascicular surgery: Technological considerations and instrumentation -- Standard parafascicular approaches to subcortical regions -- Trans-sulcal, channel-based parafascicular surgery: Basic concepts and a general overview -- Trans-sulcal, channel-based parafascicular surgery for brain metastases -- Trans-sulcal, channel-based parafascicular surgery for gliomas and other primary, intrinsic subcortical tumors -- Trans-sulcal, channel-based parafascicular biopsy techniques -- Trans-sulcal, channel-based parafascicular surgery for intraventricular lesions -- Trans-sulcal, channel-based parafascicular surgery for intracerebral hematoma (ICH) -- Trans-sulcal, channel-based parafascicular surgery for cavernous angiomas and other vascular lesions -- Trans-sulcal, channel-based parafascicular surgery for tumors; Adjunctive measures and techniques -- Case selection and surmounting the learning curve -- Future directions.
    Abstract: This book will be the definitive reference on surgery of the subcortical region. It comprehensively discusses all aspects of treatment of subcortical and intraventricular lesions, including neuroanatomy and neuroimaging of the subcortical space, principles of parafascicular subcortical channel-based surgery, common indications and approaches, and focused chapters for common subcortical lesions. The first section of the reference focuses on the intricate anatomy and neuro-imaging of the subcortical space and ventricular system, with special emphasis on intricate white matter tracts and diffusion tractography imaging. The next section of the book discusses principles of both open and parafascicular, channel-based approaches to subcortical and intraventricular lesions, in addition to workhorse approaches to common subcortical compartments. Finally, specific pathological subcortical lesions that can be commonly addressed via parafascicular channel-based approaches, including brain metastases, gliomas, and intracerebral hemorrhage are addressed. Authored by experts in the field of subcortical neurosurgery, this book was developed to provide a unique, comprehensive text for neurosurgeons, neuro-radiologists, and trainees from a variety of specialties interested in evolving minimally disruptive access and treatment of the subcortical space.
    Type of Medium: Online Resource
    Pages: XII, 257 p. 94 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030951535
    DDC: 610
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Microbiology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Microbial ecology. ; Industrial microbiology. ; Microbiology. ; Environmental Engineering/Biotechnology. ; Microbial Ecology. ; Industrial Microbiology.
    Description / Table of Contents: 1. Sulfate-reducing prokaryotes: Changing paradigms -- 2. Characteristics and taxonomy -- 3. Reduction of sulfur and nitrogen compounds -- 4. Electron transport proteins and cytochromes -- 5. Systems contributing to the energetics of SRP -- 6. Cell biology and metabolism -- 7. Geomicrobiology, biotechnology, and industrial applications -- 8. Biocorrosion -- 9. Ecology of dissimilatory sulfate reducers: Life in extreme conditions and activities of SRB -- 10. Interactions of SRB with animals and plants.
    Abstract: The abundance of sulfate-reducing bacteria and archaea (SRBA) is impressive and new isolates are being reported continuously. A few decades ago, only two genera of dissimilatory sulfate reducers had been identified and as of 2018, 92 genera containing more than 420 species of SRB and several species of archaea have been isolated. This book addresses the historical background of SRBA research and reviews the current status of research examining the growth of these anaerobic microorganisms. Additionally, this book covers metabolic and genomic diversity, enzymatic processes, response to stress, biocorrosion of ferrous metals, biogeochemical processes and interactions with other microorganisms in the anaerobic biosphere. It highlights the unique cellular and molecular features of these microorganisms, discusses the production and consumption of gases and reviews genomic content influencing their metabolic capabilities. Examples are provided of detoxification reactions to alleviate pollution situations, growth in in hostile environments including low nutrient availability, and the effects of sulfate-reducing bacteria (SRB) on human and animal hosts.
    Type of Medium: Online Resource
    Pages: XI, 564 p. 62 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030967031
    DDC: 579
    Language: English
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  • 5
    Keywords: Cancer. ; Cytology. ; Clinical biochemistry. ; Cancer Biology. ; Cell Biology. ; Medical Biochemistry.
    Description / Table of Contents: Chapter 1: Small leucine-rich proteoglycans regulate cancer cell growth, apoptosis-and associated inflammation -- Chapter 2: The role of decorin in cancer -- Chapter 3: The mystery of syndecan-1 in tumor development and progression -- Chapter 4:Syndecan-2 Biology and its Role in Colorectal Carcinoma -- Chapter 5: Versican in Tumor Progression, Tumor-Host Interactions and Cancer Immunotherapy -- Chapter 6:Circulating proteoglycans/glycosaminoglycans as cancer biomarkers -- Chapter 7: Hyaluronan in the Extracellular Matrix of hematological and solid tumors. Its biological effects" -- Chapter 8: Heparanase: a paramount enzyme for cancer initiation, progression and metastasis -- Chapter 9: Laminins and matrix metalloproteinases connection: a subtle relationship that can go wrong in a tumor context, particularly if CD44 gets involved -- Chapter 10:Basement membrane, collagen, and fibronectin: physical interactions with cancer cells -- Chapter 11: Integrins in cancer: re-focusing on the tumor microenvironment -- Chapter 12: Adipose compounds in breast tumor extracellular matrix -- Chapter 13: Extracellular matrix as a metabolic niche in cancer -- Chapter 14: The role of inflammatory cells in tumor angiogenesis -- Chapter 15: Cancer angiogenesis and its master regulator perlecan -- Chapter 16: The microRNA-extracellular matrix interplay in breast cancer -- Chapter 17: The impact of the extracellular matrix on immunotherapy success -- Chapter 18: Exploiting hyaluronan-CD44 network in tumor therapy.
    Abstract: This book introduces the most important and best studied extracellular and pericellular molecules of the tumor microenvironment. It gives a comprehensive overview of their role in tumor development and cancer progression. Twelve chapters deal with the biochemical and biophysical background of extracellular matrix (ECM) changes in the tumor stroma compared to the physiological state. The reader learns about the major ECM components that are deregulated during cancer development and how they are associated with cancer progression associated with survival, inflammation process, among others. These are followed by recent data about the cooperative activity of extracellular matrix in tumor metabolism, promoting cancer progression. Two chapters focus specifically on the critical role of the ECM in tumor angiogenesis, linking this process to cellular infiltration and metastatic behavior of tumors. The final part describes how the ECM influences the success of immuno- and chemotherapy in cancer patients, its potential as biomarkers for diagnosis, prognosis, and therapeutic target, as well as the mechanism of resistance-associated changes in the ECM. This book is an interesting read for anyone who want to know more about ECM and cancer biology. Early career scientists can use it as an introduction to the field, offering an excellent tool for studying ECM. Advanced researchers and clinicians can gain a broader overview of the subject, considering the role of ECM for influencing every cancer hallmark as well as in the response of cancer treatments. The work serves to inspire future research and shows that the ECM should be considered as an important factor in the development of cancer therapeutics. The series "Biology of Extracellular Matrix" is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
    Type of Medium: Online Resource
    Pages: X, 494 p. 40 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030997083
    Series Statement: Biology of Extracellular Matrix, 11
    DDC: 571.978
    Language: English
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  • 6
    Keywords: Plant anatomy. ; Nanotechnology. ; Plants Development. ; Plant biotechnology. ; Plant Anatomy and Morphology. ; Nanotechnology. ; Plant Development. ; Plant Biotechnology.
    Description / Table of Contents: Preface -- Global Importance and Cycling of Nanoparticles -- Environmental Emissions of Nanoparticles -- Bio- and Geo-Transformation and Bioavailability of Nanoparticles -- Interaction of Nanoparticles to Soil Pollutants -- Impact of Nanoparticles to Soil Systems -- Too Much or Too Little? A Review of the Connundrum of Nanoparticles -- Application and Use of Nanoelements in Combating Plant Nutrition -- Role of Nanoparticles in Remediation of Contaminated Soils -- Biochemical, Molecular and Ultrastructural Aspects in Phytoremediation of Nanoparticles Subjected to Unfertilized Soil -- Nanomaterials: A New Approach in Biofortification -- Applications and Implications of Nano-Fertilizers in Food Industries -- Nanobiosensors Based on Agri-Biomass -- Nanoparticles Uptake and Translocation in Plants -- Risks and Concerns of Use of Nanoparticles in Agriculture -- Mechanism of Nanoparticles Mediated Alleviating Biotic and Abiotic Stresses in Agricultural Crops -- Role of Nanoparticles in Environment, Human, and Animals Under Contaminated Soil -- Cytotoxic and Genotoxic Aspects of nanoparticles Interactions with Plant Systems -- Nanoparticles and its Effects on Growth, Yield, and Crop Quality Cultivated Under Polluted Soil -- Impact of nanoparticles of Modulations of Genes and Secondary Metabolites in Plants -- Interaction of Nanoparticles with Plant Growth Promoting Rhizobacteria in Polluted Soil -- Interaction of Nanomaterials with Plant Metabolism -- Bibliography -- Index.
    Abstract: NNanotechnology has shown great potential in all spheres of life. With the increasing pressure to meet the food demands of rapidly increasing population, thus, novel innovation and research are required in agriculture. The principles of nanotechnology can be implemented to meet the challenges faced by agricultural demands. Major challenges include the loss of nutrients in the soil and nutrient-deficient plants, which result in a lower crop yield and quality. Subsequently, consumption of such crops leads to malnourishment in humans, especially in underprivileged and rural populations. One convenient approach to tackle nutrient deficiency in plants is via the use of fertilizers; however, this method suffers from lower uptake efficiency in plants. Another approach to combat nutrient deficiency in humans is via the use of supplements and diet modifications; however, these approaches are less affordably viable in economically challenged communities and in rural areas. Therefore, the use of nano-fertilizers to combat this problem holds the greatest potential. Additionally, nanotechnology can be used to meet other challenges in agriculture including enhancing crop yield, protection from insect pests and animals, and by use of nano-pesticides and nano-biosensors to carry out the remediation of polluted soils. The future use of nanomaterials in soil ecosystems will be influenced by their capability to interact with soil constituents and the route of nanoparticles into the environment includes both natural and anthropogenic sources. The last decade has provided increasing research on the impact and use of nanoparticles in plants, animals, microbes, and soils, and yet these studies often lacked data involving the impact of nanoparticles on biotic and abiotic stress factors. This book provides significant recent research on the use of nano-fertilizers, which can have a major impact on components of an ecosystem. This work should provide a basis to further study these potential key areas in order to achieve sustainable and safe application of nanoparticles in agriculture.
    Type of Medium: Online Resource
    Pages: XI, 394 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030973896
    Series Statement: Sustainable Plant Nutrition in a Changing World,
    DDC: 571.32
    Language: English
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  • 7
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Sustainability. ; Geography. ; Environmental management. ; Sustainability. ; Regional Geography. ; Environmental Management.
    Description / Table of Contents: Chapter1. Global Mountain Awareness -- Chapter2. An International Mountain Involvement: The Beginnings -- Chapter3. Mountain Strategy in Munich, 1974: On Track to the Himalaya -- Chapter4. Darjeeling: Personal Awakening to High Mountains and Refugees -- Chapter5. Moscow and the Caucasus: The IGU in the Cold War -- Chapter6. United Nations University: Agency with a Mountain Mission -- Chapter7. Himalayan Reconnaissance 1978: Deforestation, Landslides, and Farmers -- Chapter8. The China Connection: Privileged Entry to a Closed Country -- Chapter9. Beyond Lhasa: Opening China to Collaborative Mountain Research -- Chapter10. Breakthrough: Environmental Degradation Theory Overturned -- Chapter11. China Revisited 1985: Yunnan and the Jade Dragon Snow Mountains -- Chapter12. The Mohonk Process: Mobilization of the Mountain Advocates -- Chapter13. Mountain Road to Rio: The UN Earth Summit 1992 -- Chapter14. Return to China 1991–1996: Mountain People of Yunnan and Mass Tourism -- Chapter15. Roof of the World: The Pamir, 1999: “A Catastrophe of Biblical Proportions” -- Chapter16. Threatened Disasters in the Pamir and Himalaya -- Chapter17. The Evolution of the Mountain Cause. .
    Abstract: This second edition of “Sustainable Mountain Development” is a history of the development of mountain environmental awareness from its origins during the Stockholm Conference on the Environment in 1973. This provided intellectual input into UNESCO’s MAB Programme, especially MAB-6 (Impact of Human Activities on Mountain Environments), The International Geographical Union’s commission on mountains, and The United Nations University’s (UNU) mountain project, the latter initiated in 1978. All this research and intellectual activity saw its maturation during the 1992 Earth Summit held in Rio de Janeiro. The major document universally agreed upon was AGENDA 21, with Chapter 13 concentrating on mountain environmental problems which led to 2002 being dedicated as The International Year of Mountains, and December 17th as International Mountain Day. The research that inspired this book, accompanied by intensive environmental and political activity, was initially propagated by a small group of colleagues that ultimately expanded to a world-wide endeavour. The work was recognised by three awards of the King Albert Gold Medal, two RGS Gold Medals, approved by Her Majesty Queen Elizabeth II, and countless other awards. It led to the founding of the International Mountain Society in 1980 and its quarterly journal “Mountain Research and Development” (1981). The work expanded into subsequent research efforts, including specific assessments of projected major catastrophes such as the status of the potential outbreak of glacier lakes (GLOFs), the impacts of climate warming, and incorporation of the mountain subsistence men and women whose environmental knowledge was enthusiastically recognized. This edition provides a new epilogue, which outlines the considerable changes to world environmental assessment since the establishment of 2002 as the International Year of Mountains, and notes that 2022 has been designated as the International Year of Sustainable Mountain Development.
    Type of Medium: Online Resource
    Pages: XVI, 301 p. 152 illus., 136 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030960292
    DDC: 304.2
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Machine learning. ; Artificial intelligence. ; Medical policy. ; Transportation engineering. ; Traffic engineering. ; Business logistics. ; Machine Learning. ; Artificial Intelligence. ; Intelligence Infrastructure. ; Health Policy. ; Transportation Technology and Traffic Engineering. ; Logistics.
    Description / Table of Contents: Applying Deep Learning to Predict Civic Purpose Development: Within the Smart City Context -- Convolution Neural Network Scheme for Detection of Electricity Theft in Smart Grids -- Helping Hand: A GMM Based Real time Assistive Device for Disabled Using Hand Gestures -- A Review on Hand Gesture and Sign Language Techniques for Hearing Impaired Person -- DriveSense: Adaptive System for Driving Behaviour Analysis and Ranking -- Classification and Tracking of Vehicles Using Videos Captured by Unmanned Aerial Vehicles -- Tracking Everyone and Everything in Smart Cities with an ANN Driven Smart Antenna -- Wavelet based Saliency and Ensemble Classifier for Pedestrian Detection in Infrared Images -- A Survey of Emerging Applications of Machine Learning in the Diagnosis and Management of Sleep Hygiene and Health in the Elderly Population -- Smart City Traffic Patterns Prediction Using Machine Learning.
    Abstract: This book discusses the application of different machine learning techniques to the sub-concepts of smart cities such as smart energy, transportation, waste management, health, infrastructure, etc. The focus of this book is to come up with innovative solutions in the above-mentioned issues with the purpose of alleviating the pressing needs of human society. This book includes content with practical examples which are easy to understand for readers. It also covers a multi-disciplinary field and, consequently, it benefits a wide readership including academics, researchers, and practitioners.
    Type of Medium: Online Resource
    Pages: VIII, 226 p. 179 illus., 153 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031088599
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    DDC: 006.31
    Language: English
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  • 9
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Food science. ; Fungi. ; Mycology. ; Microbiology. ; Pharmacology. ; Ecology . ; Food Science. ; Fungi. ; Pharmacology. ; Ecology.
    Description / Table of Contents: Ch-01 : Introduction -- Ch-2. Ecology of Fungal Food Spoilage -- Ch 3. Naming and Classifying Fungi -- Ch-4 Methods for Enumeration, Isolation and Identification -- Ch-5 Primary Keys and Miscellaneous Fungi -- Ch 6- Zygomycetes -- Ch 7 Penicillium and Talaromyces -- Ch 8 Aspergillus and Related Teleomorphs -- Ch 9 Xerophiles -- Ch 10 - Yeasts -- Ch 11: Fresh and Perishable Foods -- Ch 12- Spoilage of Stored, Processed and Preserved Foods -- Ch 13: Mycotoxins.
    Abstract: The first three editions of Fungi and Food Spoilage established, then consolidated, a reputation as the leading book on foodborne fungi. It details media and methods for isolation and identification, descriptions of species, and information on their physiology, ecology and mycotoxin formation. It is an invaluable reference for food microbiologists investigating fungal food spoilage problems, both in field crops and processed foods, and the likelihood of mycotoxin production in either. The Fourth Edition incorporates major differences from the Third: multiple changes in nomenclature due to changes in the International Code of Nomenclature for algae, fungi and plants; many taxonomic changes due to improvements in, and more widespread application of, molecular methods in taxonomy; the introduction of colour colony photographs where appropriate; and a new chapter on mycotoxins. The introductory chapters of the book deal with the ecology of food spoilage, and provide an overview of how food processing, packaging and storage parameters influence fungal growth. A subsequent chapter overviews the fundamentals of naming and classifying fungi. Morphological methods and media suitable for low cost and effective isolation, enumeration and identification of foodborne fungi are provided, together with many more specialised media and techniques. The major part of the book provides keys, descriptions and illustrations of all yeasts and filamentous fungi commonly encountered in foods. Other known characteristics of the species, including physiology and ecology are included. Chapters on the types and species of fungi likely to be found in fresh, harvested and variously processed foods are followed by a new chapter on mycotoxins, both major and minor, their sources, both fungal and food, and their implications for human health. The broad and practical nature of the coverage will appeal to microbiologists, mycologists and biotechnologists in the food industry, as well scientists in academic, research and public health institutions. Drs Pitt and Hocking worked for CSIRO Food for more than 100 years combined. Both are now retired from CSIRO: Dr Pitt continues to work part time with Microbial Screening Technologies, a biodiscovery company.
    Type of Medium: Online Resource
    Pages: XXI, 645 p. 186 illus., 110 illus. in color. , online resource.
    Edition: 4th ed. 2022.
    ISBN: 9783030856403
    DDC: 641.3
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmaceutical chemistry. ; Drug delivery systems. ; Drugs Design. ; Pharmacology. ; Pharmacy. ; Proteins Synthesis. ; Pharmaceutics. ; Drug Delivery. ; Structure-Based Drug Design. ; Pharmacology. ; Pharmacy. ; Protein Synthesis and Translation.
    Description / Table of Contents: Basic Concepts of Design of Peptide based Therapeutics -- Computational Methods in Peptide Based Drug Design -- Synthesis, Purification, and Characterization of Linear and Cyclic Peptides -- Large Scale Synthesis of Peptides, Manufacturing Peptide Therapeutics -- Stability of Peptides -- Peptide Delivery Systems -- Liposomes and Nanoparticle Formulations for Peptide Delivery -- Delivery of Peptides Across the Blood-brain Barrier (BBB) -- Peptide Therapeutics Regulatory Considerations.
    Abstract: This book explains how peptide-based drug design works, what steps are needed to develop a peptide-based therapeutic, and challenges in synthesis as well as regulatory issues. It covers the design concept of peptide therapeutics from fundamental principles using structural biology and computational approaches. The chapters are arranged in a linear fashion. A fresh graduate or a scientist who works on small molecules can use this to follow the design and development of peptide therapeutics to use as understanding the basic concepts. Each chapter is written by experts from academia as well as industry. Rather than covering extensive literature, the book provides concepts of design, synthesis, delivery, as well as regulatory affairs and manufacturing of peptides in a systematic way with examples in each case. The book can be used as a reference for a pharmaceutical or biomedical scientist or graduate student who wants to pursue their career in peptide therapeutics. Some chapters will be written as a combination of basic principles and protocol so that scientists can adopt these methods to their research work. The examples provided can be used to perform peptide formulation considerations for the designed peptides. The book has nine chapters, and each chapter can be read as an independent unit on a particular concept.
    Type of Medium: Online Resource
    Pages: IX, 317 p. 52 illus., 42 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031045448
    Series Statement: AAPS Advances in the Pharmaceutical Sciences Series, 47
    DDC: 615.19
    Language: English
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