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  • 2020-2024  (7)
  • 1980-1984
  • 2022  (7)
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  • 1
    Online Resource
    Online Resource
    Targets of Cancer Diagnosis and Treatment : Ion Transport in Tumor Biology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Pharmacology. ; Human physiology. ; Internal medicine. ; Physiology. ; Biomedical Research. ; Medical Biochemistry. ; Pharmacology. ; Human Physiology. ; Internal Medicine. ; Physiology.
    Description / Table of Contents: Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges -- Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer -- Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk -- Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics -- Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research -- Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions -- Ion Transport and Radioresistance -- Ion Transporting Proteins and Cancer: Progress and Perspectives.
    Abstract: Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges Alina L. Capatina, Dimitris Lagos, and William J. Brackenbury Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer Ana Ramírez, Janice García-Quiroz, Luis Aguilar-Eslava, Yesennia Sánchez-Pérez, and Javier Camacho Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk Jerry J. Fan and Xi Huang Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics Umberto Banderali, Luigi Leanza, Najmeh Eskandari, and Saverio Gentile Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research Marie Potier-Cartereau, William Raoul, Gunther Weber, Karine Mahéo, Raphael Rapetti-Mauss, Maxime Gueguinou, Paul Buscaglia, Caroline Goupille, Nelig Le Goux, Souleymane Abdoul-Azize, Thierry Lecomte, Gaëlle Fromont, Aurélie Chantome, Olivier Mignen, Olivier Soriani, and Christophe Vandier Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions Jason T. Anderson, Kevin M. Huang, Maryam B. Lustberg, Alex Sparreboom, and Shuiying Hu Ion Transport and Radioresistance Bastian Roth and Stephan M. Huber Ion Transporting Proteins and Cancer: Progress and Perspectives Mustafa B. A. Djamgoz.
    Type of Medium: Online Resource
    Pages: X, 277 p. 30 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031039942
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology, 183
    URL: https://doi.org/10.1007/978-3-031-03994-2
    DOI: 10.1007/978-3-031-03994-2
    DDC: 610.72
    Language: English
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  • 2
    Online Resource
    Online Resource
    From Malignant Transformation to Metastasis : Ion Transport in Tumor Biology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Pharmacology. ; Human physiology. ; Physiology. ; Biomedical Research. ; Medical Biochemistry. ; Pharmacology. ; Human Physiology. ; Physiology.
    Description / Table of Contents: How Reciprocal Interactions Between the Tumor Microenvironment and Ion Transport Proteins Drive Cancer Progression -- Ion Channels, Transporters, and Sensors Interact with the Acidic Tumor Microenvironment to Modify Cancer Progression -- Role of pH Regulatory Proteins and Dysregulation of pH in Prostate Cancer -- Calcium-Permeable Channels in Tumor Vascularization: Peculiar Sensors of Microenvironmental Chemical and Physical Cues -- Circulating Tumor Cells: Does Ion Transport Contribute to Intravascular Survival, Adhesion, Extravasation, and Metastatic Organotropism?.
    Abstract: How Reciprocal Interactions Between the Tumor Microenvironment and Ion Transport Proteins Drive Cancer Progression Line O. Elingaard-Larsen, Michala G. Rolver, Ester E. Sørensen, and Stine F. Pedersen Ion Channels, Transporters, and Sensors Interact with the Acidic Tumor Microenvironment to Modify Cancer Progression Ebbe Boedtkjer Role of pH Regulatory Proteins and Dysregulation of pH in Prostate Cancer Larry Fliegel Calcium-Permeable Channels in Tumor Vascularization: Peculiar Sensors of Microenvironmental Chemical and Physical Cues Giorgia Scarpellino, Luca Munaron, Anna Rita Cantelmo, and Alessandra Fiorio Pla Circulating Tumor Cells: Does Ion Transport Contribute to Intravascular Survival, Adhesion, Extravasation, and Metastatic Organotropism? Christian Stock.
    Type of Medium: Online Resource
    Pages: XV, 175 p. 40 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030998004
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology, 182
    URL: https://doi.org/10.1007/978-3-030-99800-4
    DOI: 10.1007/978-3-030-99800-4
    DDC: 610.72
    Language: English
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  • 3
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    Time, Migration and Forced Immobility (2022)
    Bristol University Press
    Details
    Publication Date: 2022-03-30
    Description: ePDF and ePUB available Open Access under CC-BY-NC-ND licence. This book is concerned with the effects of migration policy making in Europe on migrants in the Global South and links insights on immobility to social theories of time to examine the human consequences of current migration dynamics from the perspectives of migrants themselves. Based on in-depth ethnographic research, this is an invaluable learning resource that aims to challenge current international migration politics and policy-making.
    Keywords: EU migration policy; Immobility; Migration; Morocco; Social theories of time ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFD Refugees & political asylum ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFM Social mobility ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFN Migration, immigration & emigration
    Language: English
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    Format: image/jpeg
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  • 4
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    Potassium, rubidium, and cesium contents in soil along a continental transect in the Chilean Coastal Cordillera (2022)
    PANGAEA
    Details
    Publication Date: 2024-06-12
    Description: A tracer experiment was conducted in three study sites along a continental transect from arid to humid-temperate conditions in the Chilean Coastal Cordillera. The objective was to determine the short-term (〈1 year) plant nitrogen (N) and potassium (K) acquisition from topsoil (A-Bw horizons), subsoil (Bw-BCw horizons), and saprolite (below BCw horizon). In February and March 2016, ¹⁵N (as Na¹⁵NO₃, 99 at%) and the K analogs rubidium (as RbCl) and cesium (as CsCl) were injected in three soil depths around the focal plants: Gutierrezia resinosa (H.&A.) B. in the northernmost site (arid shrubland), Aristeguietia salvia (C.) K.&R. in the intermediate site (mediterranean woodland), and Araucaria araucana (M.) K. in the southernmost site (temperate rainforest). The injection holes were drilled with an auger and the excavated soil material was collected to determine soil N, K, Rb, and Cs contents. In November 2016, shoot and root material of labeled and unlabeled plants was collected. The N, K, Rb, and Cs contents and the stable isotope ratios of δ¹⁵N (expressed as δ¹⁵N) in plant tissue were measured. The tracer recovery by plants was determined by the ¹⁵N enrichment and the shift of Rb and Cs contents normalized to the K content between reference plants and labeled plants. The data set contains the K, Rb, and Cs contents in soil.
    Keywords: Aspect; Caesium; Chile; DEPTH, soil; Depth, soil, maximum; Depth, soil, minimum; Device type; Event label; Inductively coupled plasma - mass spectrometry (ICP-MS); Inductively Coupled Plasma - Optical Emission Spectrometry (ICP-OES); LATITUDE; LONGITUDE; MULT; Multiple investigations; National_Park_La_Campana; National_Park_Nahuelbuta; Potassium; Replicate; Reserva_Santa_Gracia; Rubidium; Sample material; Site
    Type: Dataset
    Format: text/tab-separated-values, 1490 data points
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  • 5
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    Element contents and stable isotope analysis in plants from a nitrogen and potassium tracer experiment in the Chilean Coastal Cordillera (2022)
    PANGAEA
    Details
    Publication Date: 2024-06-12
    Description: A tracer experiment was conducted in three study sites along a continental transect from arid to humid-temperate conditions in the Chilean Coastal Cordillera. The objective was to determine the short-term (〈1 year) plant nitrogen (N) and potassium (K) acquisition from topsoil (A-Bw horizons), subsoil (Bw-BCw horizons), and saprolite (below BCw horizon). In February and March 2016, δ¹⁵N (as Na¹⁵NO₃, 99 at%) and the K analogs rubidium (as RbCl) and cesium (as CsCl) were injected in three soil depths around the focal plants: Gutierrezia resinosa (H.&A.) B. in the northernmost site (arid shrubland), Aristeguietia salvia (C.) K.&R. in the intermediate site (mediterranean woodland), and Araucaria araucana (M.) K. in the southernmost site (temperate rainforest). The injection holes were drilled with an auger and the excavated soil material was collected to determine soil N, K, Rb, and Cs contents. In November 2016, shoot and root material of labeled and unlabeled plants was collected. The N, K, Rb, and Cs contents and the stable isotope ratios of N (expressed as δ¹⁵N) in plant tissue were measured. The tracer recovery by plants was determined by the δ¹⁵N enrichment and the shift of Rb and Cs contents normalized to the K content between reference plants and labeled plants.The data set contains the N, K, Rb, and Cs contents as well as the stable isotope ratios of N in plant biomass.
    Keywords: Aspect; Atom percent, 15N; Biomass, dry mass; Caesium; Chile; DEPTH, soil; Element analyser isotope ratio mass spectrometer (EA-IRMS); Event label; Inductively coupled plasma - mass spectrometry (ICP-MS); Inductively Coupled Plasma - Optical Emission Spectrometry (ICP-OES); LATITUDE; LONGITUDE; MULT; Multiple investigations; National_Park_La_Campana; National_Park_Nahuelbuta; Nitrogen; Number; Potassium; Replicate; Reserva_Santa_Gracia; Rubidium; Sample material; Site; Tracer injection; δ15N
    Type: Dataset
    Format: text/tab-separated-values, 1805 data points
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    DATA PANGAEA
  • 6
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    Mixed Layer Depth Promotes Trophic Amplification on a Seasonal Scale (2022)
    AGU (American Geophysical Union) | Wiley
    Details
    Publication Date: 2024-02-07
    Description: The Humboldt Upwelling System is of global interest due to its importance to fisheries, though the origin of its high productivity remains elusive. In regional physical-biogeochemical model simulations, the seasonal amplitude of mesozooplankton net production exceeds that of phytoplankton, indicating “seasonal trophic amplification.” An analytical approach identifies amplification to be driven by a seasonally varying trophic transfer efficiency due to mixed layer variations. The latter alters the vertical distribution of phytoplankton and thus the zooplankton and phytoplankton encounters, with lower encounters occurring in a deeper mixed layer where phytoplankton are diluted. In global model simulations, mixed layer depth appears to affect trophic transfer similarly in other productive regions. Our results highlight the importance of mixed layer depth for trophodynamics on a seasonal scale with potential significant implications, given mixed layer depth changes projected under climate change.
    Type: Article , PeerReviewed , info:eu-repo/semantics/article
    Format: text
    Format: text
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  • 7
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    Plant traits affect vertical accretion of salt marshes (2022)
    Elsevier
    Details
    Publication Date: 2024-02-07
    Description: The current climate crisis is associated with rising sea levels, which raises the concerning prospect of losing coastal ecosystems, such as salt marshes. Where inland migration is impossible, salt marshes will only persist if their vertical accretion exceeds the rate of sea-level rise. Positive vertical accretion is mainly driven by sedimentation, whereas negative vertical accretion is driven by erosion and soil compaction, among others. These processes can be influenced by abiotic and biotic factors. The biotic factors, best described by plant functional traits of the salt-marsh vegetation, are, however, not well understood. We assembled a large dataset of 336 plots with vertical accretion time series and plant abundances and coupled it with trait data from salt marsh species of the German Wadden Sea, covering natural unmanaged, anthropogenic unmanaged, and grazed marshes. By using multiple logistic regression analyses, we studied the effects of plant functional traits and distance to the marsh edge on vertical accretion. Mean vertical accretion was in the range of recent sea level rise, except for plots on elevated grazed marshes. There were, however, pronounced local differences in vertical accretion. Positive accretion increased with distance to marsh edge and increasing leaf and stem roughness, described by specific stem length, canopy height, stem mass, leaf mass and leaf area. Except on grazed marshes, leaf traits contributed more strongly to the explanation of positive accretion than stem traits. Negative accretion by e.g., erosion was facilitated by low specific root length and low root and rhizome mass, i.e., lower anchoring capacity. To better assess coastal resilience to sea level rise, our findings suggest (i) to include these effect traits in models and experimental analyses of salt marsh vertical accretion and (ii) to consider effects of vegetation roughness on accretion in salt marsh management schemes.
    Type: Article , PeerReviewed
    Format: text
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