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  • R5-920  (16)
  • Environmental Sciences.  (5)
  • 2020-2024  (21)
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  • 2021  (21)
  • 1
    Keywords: Toxicology. ; Pharmacology. ; Environment. ; Toxicology. ; Pharmacology. ; Environmental Sciences.
    Description / Table of Contents: Overview of Nanotoxicology in Humans and the Environment: Developments.-The potential adverse effects of engineered nanomaterial exposure to human health following pulmonary, oral and dermal exposure @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US; mso-fareast-language:ZH-CN;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:11.0pt; mso-ansi-font-size:11.0pt; mso-bidi-font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:EN-US; mso-fareast-language:EN-US;}.MsoPapDefault {mso-style-type:export-only; margin-bottom:10.0pt; line-height:115%;}div.WordSection1 {page:WordSection1;} -- Nanotoxicology in the Environment -- Nano-enabled consumer products – inventories, release, and exposures -- Factors affecting nanoparticle dose–exposure and cell response -- Mapping Exposure onto Nanoscale Toxicity Measures -- Nanotoxicology and risk perception among public and elite groups -- EU Regulations and Nanotechnology Innovation. @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:10.0pt; 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mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:3 0 0 0 1 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US; mso-fareast-language:ZH-CN;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:11.0pt; mso-ansi-font-size:11.0pt; mso-bidi-font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:EN-US; mso-fareast-language:EN-US;}.MsoPapDefault {mso-style-type:export-only; margin-bottom:10.0pt; line-height:115%;}div.WordSection1 {page:WordSection.
    Abstract: The book covers the area of ‘Nanotoxicology’ but primarily from the point of view of nanotoxicology at the interface with other disciplines including human toxicology; environmental toxicology; characterization, dose and transformations; regulation; public and elite group perceptions; and interactions with innovation.Nanotoxicology in Humans and the Environment is written for researchers in nanotoxicology in academia, industry, government, and research students. Given the rapid development, the maturing of the discipline and its importance in current regulation and industry development (eg REACH, TSCA), the book is very timely.
    Type of Medium: Online Resource
    Pages: V, 259 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030798086
    Series Statement: Molecular and Integrative Toxicology,
    DDC: 615.90072
    Language: English
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  • 2
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Environment. ; Environmental management. ; Sustainability. ; Food security. ; Environmental Sciences. ; Environmental Management. ; Sustainability. ; Food Security.
    Description / Table of Contents: Chapter1 -- Earth’s Human Carrying Capacity: The Basics -- Chapter2 -- Water: A Limit On Our Earth’s Carrying Capacity -- Chapter3 -- Food Security/Insecurity, Food Systems -- Chapter4 -- Impact of Global Warming/Climate Change On Food Security 2020 -- Chapter 5 -- Sanitation: Waste Generation/Capture/Disposal Status 2020 -- Chapter6 -- Access To Natural Resources Not Water Or Food 2020 -- Chapter7 -- Global Warming And Water 2050: More People, Yes; Less Ice, Yes; More Water, Yes; More Fresh Water, Probably; More Accessible Fresh Water -- Chapter8 -- Food 2050 - More Mouths To Feed: Food Availability and Access -- Chapter9.-Sanitation 2050 -- Chapter10 -- Natural Resources Beyond Water And Food 2020 To 2050 -- Chapter11 -- Economic Realities in 2020 Populations: What do they Portend for 2050? 2100?
    Abstract: This book focuses on the Earth’s carrying capacity to service the needs of its human populations as well as preserve the ecosystems that provide natural resources that sustain life and support human activities in 2020 and later in the century (2050 and beyond). It addresses the two principal factors that challenge the limits of the carrying capacity: growing populations/demographic moves and global warming/climate change. It also covers the effects that these factors have on water availability, food security, sanitation and natural resources. The status of these basic needs that sustain life and societal activities with respect to population increases and global warming driven climate changes are discussed on two time frames. One with respect to the 2020 and the other with measured and computer guided projected future impacts later as the century progresses to 2050 and later, Attention is given to Africa, Asia, and somewhat for South America because of their projected increases in population. The purpose of the book is to provide those in decision-making roles and those that advise them with a sound set of facts and figures to think about to support their decisions/actions. A secondary purpose is to present data that stresses the need to act now, firmly and with investment to plan to adapt to changing conditions rather than wait until forced to do so. The book also discusses how the COVID-19 pandemic has affected the world’s societies and how they have reacted. The book will be of use to students in first/second year of college/university programs in Environmental Sciences/Studies, demographics, and ancillary fields such as agriculture science, urban/land use planners, political science, public health, and consultants at academic and professional levels.
    Type of Medium: Online Resource
    Pages: XIII, 154 p. 3 illus., 2 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030734763
    DDC: 333.7
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Environment. ; Physical geography. ; Environmental sciences Social aspects. ; Environmental policy. ; Environmental Sciences. ; Physical Geography. ; Environmental Social Sciences. ; Environmental Policy.
    Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: Climate Change -- Chapter 3: Extinctions -- Chapter 4: Thresholds -- Chapter 5: Resources -- Chapter 6: Population -- Chapter 7: Agriculture -- Chapter 8: Urbanization -- Chapter 9: Practical Solutions.
    Abstract: This textbook explores the growing area of human-environment interaction. We live in the Anthropocene, an era dominated by humans, but also by the positive yet destructive environmental feedbacks that are poised to completely reset the relationships between nature and society. Modern and historic political, social, and cultural processes and physical landscape responses determine the intensity of these impacts. Yet different cultural groups, political and economic entities view, react to, and impact these human-environmental processes in spatially distinct and divergent ways. Providing an accessible, up-to-date, approach to human-environment interactions with balanced coverage of both social and natural science approaches to core environmental issues, this textbook is an integrative, multi-disciplinary offering that discusses environmental issues and processes within the context of human societies. The book begins by addressing the three most pressing issues of our time: climate change, threshold exceedance, and the 6th mass extinction. From there the authors identify within chapters on resources, population, agriculture and urbanization what precipitated and continues to sustain these three issues. They end with a chapter outlining some practical solutions to our human-environment crises. The book will be a valuable resource for interdisciplinary environment related courses bridging the gap between the social and natural sciences, human geographies and physical geographies. Mark R. Welford is Head and Professor of Geography at the University of Northern Iowa, USA. He is the author of Geographies of Plague Pandemics: The Spatial-Temporal Behavior of Plague to the Modern Day. He is also a co-Principal Investigator on a National Science Foundation RAPID grant entitled “Tracking and Understanding Spatiotemporal Dynamics of the COVID-19 Pandemic in the Arctic.” Robert A. Yarbrough is Associate Professor of Geography in the Department of Geology and Geography at Georgia Southern University, USA. His research areas include nature-society geographies, critical cultural geographies, and immigration. .
    Type of Medium: Online Resource
    Pages: IX, 249 p. 23 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030560324
    DDC: 333.7
    Language: English
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  • 4
    Keywords: Sedimentology. ; Geomorphology. ; Geochemistry. ; Paleontology . ; Paleoecology. ; Environment. ; Sedimentology. ; Geomorphology. ; Geochemistry. ; Paleontology. ; Paleoecology. ; Environmental Sciences.
    Description / Table of Contents: Part1. Introduction -- Chapter1. Introduction to limnogeology: progress, challenges, and opportunities—A tribute to Elizabeth Gierlowski Kordesch -- Part2. African Lake -- Chapter2. Modern and ancient animal traces in the extreme environments of Lake Magadi and Nasikie Engida, Kenya rift valley -- Part3. European lakes -- Chapter3. Lake level fluctuations and allochthonous lignite deposition in the Eocene pull-apart basin “Prinz von Hessen” (Hesse, Germany) - A palynological study -- Chapter4. How changes of past vegetation and human impact are documented in lake sediments: Paleoenvironmental research in Southwestern Germany, a review -- Chapter5. Large-scale slumps and associated resedimented deposits in Miocene lake basins from SE Spain -- Chapter6. Lacustrine and fluvial microbialites in the Neogene of the Ebro Basin, Spain: a summary of up to date knowledge -- Part4. North America -- Chapter7. Ecological response of ostracodes (Arthropoda, Crustacea) to lake level fluctuations in the Eocene Green River Formation, Fossil Basin, Wyoming, USA -- Chapter8. History of Great Salt Lake, Utah, USA, since the termination of Lake Bonneville -- Chapter9. What’s new about the old Bonneville Basin? Fresh insights about the modern Limnogeology of Great Salt Lake -- Chapter10. Middle Holocene hydrologic changes catalyzed by river avulsion in Big Soda Lake, Nevada, USA -- Chapter11. Diatom record of Holocene moisture variability in the San Bernardino Mountains, California, USA -- Chapter12. A 12,000 year diatom-based palaeoenvironmental record from Lago de Zirahuén, Mexico -- Chapter13. Sedimentary record of the Zacapu Basin, Michoacán, México and implications for P’urhépecha Culture during the Pre-Classic and Post-Classic Periods -- Chapter14. Stratigraphy and Sedimentology of the Upper Pleistocene to Holocene Lake Chalco drill cores (Mexico Basin) -- Chapter15. Submarine groundwater discharge as a catalyst for eodiagenetic carbonate cements within marine sedimentary basins -- Part5. South America -- Chapter16. Reconstructing paleoenvironmental conditions through integration of paleogeography, stratigraphy, sedimentology, mineralogy, and stable isotope data of lacustrine carbonates—an example from early Middle Triassic strata of southwest Gondwana, Cuyana Rift, Argentina -- Part6. Asia -- Chapter17. Modern sedimentary systems of Qinghai Lake -- Chapter18. Freshwater microbialites in Early Jurassic fluvial strata of the Pranhita-Godavari Gondwana Basin, India.
    Abstract: This book honors the career of Professor Elizabeth Gierlowski-Kordesch who was a pioneer and leader in the field of limnogeology since the 1980s. Her work was instrumental in guiding students and professionals in the field until her untimely death in 2016. This collection of chapters was written by her colleagues and students and recognize the important role that Professor Gierlowski-Kordesch had in advancing the field of limnogeology. The chapters show the breadth of her reach as these have been contributed from virtually every continent. This book will be a primary reference for scientists, professionals and graduate students who are interested in the latest advances in limnogeologic processes and basin descriptions in North and South America, Europe, Africa, and China. *Free supplementary material available online for chapters 3,11,12 and 13. Access by searching for the book on link.springer.com.
    Type of Medium: Online Resource
    Pages: XV, 592 p. 230 illus., 196 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030665760
    Series Statement: Syntheses in Limnogeology,
    DDC: 551.3
    Language: English
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  • 5
    Keywords: Environment. ; Water. ; Hydrology. ; Environmental Sciences. ; Water.
    Description / Table of Contents: Water, food security and Asian transition: A new perspective within the face of climate change -- Consolidating Drought Projections – Eastern Australia -- Planning for Climate Change and Mechanisms for Co-Operation in Southeast Asia’s Sesan, Sekong and Srepok Transboundary River Basin -- Environmental Security Issues No Longer of Secondary Importance for Regional Cooperation or Conflict: The Case of the Mekong River -- Emerging Research Needs for Water Security Enhancement -- The Threats to Urban Water Security of Indonesian Cities -- River Basin Planning for Water Security in Sri Lanka -- Water Quality Index: A Tool for Wetland Restoration -- A Framework for Implementing Integrated Water Resources Management at River Basin Level in Indonesia -- Addressing Water Security Issue: Prioritizing Reconstruction of Safe Drinking Water Schemes in 2015 Earthquake Affected Districts of Nepal -- A Study in Developing of Theoretical Framework of Urban Water Security in Indonesia -- Micro Level Vulnerability Assessment of Estuarine Islands: A Case Study from Indian Sundarban -- Assessing Water Security at District Level: A Case Study of Bangkok, Thailand -- Assessment of Water Security in Indonesia Considering Future Trends in Land Use Change, and Climate Change.-Application of Hydrological Study Methodologies Used in African Context for Water Security in Asian countries.-Implementation of Budyko Curves in Assessing Impacts of Climate Changes and Human Activities on Streamflow in the Upper Catchments of Dong Nai River Basin -- Contribution of Snow and Glacier in Hydropower Potential and its Response to Climate Change.
    Abstract: This book assesses the current water-security situation in Asia. The thematic areas of the book discuss the United Nation’s sustainable development goals with a particular focus on Goal 6 (“Ensure availability and sustainable management of water and sanitation”) and Goal 13 (“Take urgent action to combat climate change and its impacts”). Asia has been facing a number of water-related challenges for decades due to multiple factors such as increasing population, socio-economic development, urbanization and migration, and climate change now poses an additional threat. While significant efforts have been made by governments in Asia, much more work is needed to make Asian societies water-secure. Given its multi-disciplinary approach, the book is a valuable resource for researchers involved in the further development of water-security concepts, approaches, and methodologies. In addition, it helps policymakers, planners, and practitioners to formulate sustainable water- security enhancement strategies grounded in sound scientific evidence to protect human well-being.
    Type of Medium: Online Resource
    Pages: XIX, 797 p. 302 illus., 251 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783319546124
    Series Statement: Springer Water,
    DDC: 333.7
    Language: English
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  • 6
    Publication Date: 2023-12-21
    Description: Carbohydrates are extremely abundant bio-molecules; they are on all mammalian cell surfaces as well as on bacterial cell surfaces. In mammals most secreted proteins are glycosylated, with the glycan component comprising a significant amount by mass of the glycoprotein. Although, many years ago carbohydrate-protein recognition events were demonstrated as involved in invertebrate self-non self recognition, the contribution of carbohydrate-protein binding events to the mechanisms of the mammalian immune response was not embraced with the same enthusiasm. Adaptive immunity and the contribution of antibodies, T cells and T-lymphocyte sub-sets and protein antigen presentation dominated immunological theory. Unlike protein structures, carbohydrate structures are not template driven yet the numerous enzymes involved in carbohydrate biosynthesis and modification are encoded by a major component of the genome, and the expression of these enzymes is tightly regulated. As a consequence carbohydrate structures are also regulated, with different structures appearing according to the stage of cell differentiation and according to the age or health of the individual. The advent of technologies that have allowed carbohydrate structures and carbohydrate-protein binding events to be more easily interrogated has resulted in these types of interactions taking their place in modern immunology. We now know that glycans and their ligands (or lectins) are involved in numerous immunological pathways of both the innate and adaptive systems. However, it is clear that our understanding is still in its infancy, as more and more examples where carbohydrate structures contribute to aspects of the immune response are being recognised. The goal of this research topic is to explore the variety of roles undertaken by glycans and lectins in all aspects of the immune response. The particular focus is how the interactions of glycans with their ligands contribute to the mechanism of immune responses.
    Keywords: R5-920 ; RC581-607 ; Heparan sulfate ; Siglec ; HIV ; sialic acid ; hyaluronan ; galectin ; Heparanase ; Inflammation ; glycosaminoglycan ; Glycan ; bic Book Industry Communication::M Medicine
    Language: English
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  • 7
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-21
    Description: This book is comprised of important reviews and cutting-edge original research papers concerning electrospun and electrosprayed formulations in drug delivery. Electrospinning and electrospraying have, in recent years, attracted increasing attention in the pharmaceutical sector, with research in the area advancing rapidly. It is now possible to prepare extremely complex systems using multi-fluid processes, and to increase production rates to an industrial scale. Electrospun formulations can be produced under GMP conditions and are in clinical trials. In this volume, we explore a range of topics around electrospinning and electrospraying in controlled drug delivery. Four reviews cover the exciting potential of cyclodextrin-containing fibers and the many potential biomedical applications of electrospun fibers. The use of electrospinning to prepare amorphous systems and improve the dissolution rate and solubility of poorly soluble active ingredients is addressed, and the possibilities of such materials in tissue engineering are comprehensively covered. The six original research papers cover the effect of molecular properties on API release from Eudragit-based electrospun fibers; ferulic acid solid dispersions; electrospun medicines to treat psoriasis; scale up of electrospinning and its use to produce low-dose tablets; transepithelial permeation of drugs released from electrospun fibers, and the possibilities for the synergistic chemophotothermal treatment of cancer.
    Keywords: R5-920 ; RM1-950 ; tissue engineering ; cyclodextrin ; permeability ; poly (vinylpyrrolidone-co-vinyl acetate) ; crystalline ; antibacterial ; drug delivery ; homogenization ; capsaicin ; combination therapy ; high-shear mixing ; cyclodextrin-inclusion complexes ; amorphous ; high-speed electrospinning ; PMVE/MA ; aqueous solubility enhancement ; sieve analysis ; Raman mapping ; Eudragit ; nanofibers ; psoriasis ; PCL ; essential oils ; parameters ; antibiotics ; xanthan gum ; carvedilol ; amorphous composite ; coaxial electrospinning ; insoluble drug ; NIR-triggered drug release ; fast dissolution ; electrospinning ; oral drug delivery ; electrospun nanofibers ; poly-cyclodextrin ; TRPV1 ; gallic acid ; solid dispersion ; photothermal therapy ; drug release ; applications ; bic Book Industry Communication::M Medicine
    Language: English
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  • 8
    Publication Date: 2023-12-21
    Description: It is long known that many cells can shed extracellular vesicles, small membrane-enclosed cell fragments. Although the existence of extracellular vesicles has been recognized for many years, researchers are only beginning to understand their physiologic significance. Several recent studies have demonstrated that extracellular vesicles released from cells serve as a mode of cellular communication. They can carry diverse molecular payload (e.g. nucleic acids, bioactive lipids and proteins) to distal organs and recipient cells. Extracellular vesicles can be classified into three major groups: exosomes, microvesicles, and apoptotic bodies. All these types of extracellular vesicles can be found in a variety of biologic specimen and their numbers, distribution and composition may serve as biomarkers for various disorders, including cardiovascular disease. Although extracellular vesicle-mediated processes are currently best characterized in the fields of cancer biology and neurobiology, evidence is accumulating that extracellular vesicles play a key role in the pathophysiology of diabetes, thrombosis, inflammation and cardiovascular calcification. In this Research Topic, we invited review and methodological articles that advance our understanding of extracellular vesicle-related processes in vascular biology.
    Keywords: R5-920 ; Angiogenesis ; Atherosclerosis ; Extracellular vesicles ; Calcification ; Biomarkers ; Cardiovascular disease ; Inflammation ; Exosomes ; Platelets ; Heart valve ; bic Book Industry Communication::M Medicine
    Language: English
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  • 9
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    Frontiers Media SA
    Publication Date: 2023-12-21
    Description: The PI3Ks control many key functions in immune cells. PI3Ks phosphorylate PtdIns(4,5)P2 to yield PtdIns(3,4,5)P3. Initially, PI3K inhibitors such as Wortmannin, LY294002 and Rapamycin were used to establish a central role for Pi3K pathway in immune cells. Considerable progress in understanding the role of this pathway in cells of the immune system has been made in recent years, starting with analysis of various PI3K and Pten knockout mice and subsequently mTOR and Foxo knockout mice. Together, these experiments have revealed how PI3Ks control B cell and T cell development, T helper cell differentiation, regulatory T cell development and function, B cell and T cell trafficking, immunoglobulin class switching and much, much more. The PI3Kd inhibitor idelalisib has recently been approved for the treatment of B cell lymphoma. Clinical trials of other PI3K inhibitors in autoimmune and inflammatory diseases are also in progress. This is an opportune time to consider a Research Topic considering when what we have learned about the PI3K signalling module in lymphocyte biology and how this is making an impact on clinical immunology and haematology.
    Keywords: R5-920 ; RC581-607 ; B cell ; PI3K/AKT/mTOR ; Signal Transduction ; T cell ; PI3K pathway inhibitors ; bic Book Industry Communication::M Medicine
    Language: English
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  • 10
    Publication Date: 2023-12-21
    Description: Venous thromboembolism (VTE) occurs less often in children than adults and therefore remains underrecognized despite increasing in incidence. Due to the risk of mortality, short- and long-term morbidity, and increased healthcare costs associated with pediatric VTE, this entity merits better understanding and consideration. With this Research Topic, we aim to highlight some special considerations of pediatric VTE, namely risk factors and epidemiology, rare types of pediatric thrombosis and considerations unique to specific clinical patient subgroups, approaches to management and treatment, and prevention
    Keywords: R5-920 ; RJ1-570 ; Pediatrics ; Venous Thromboembolism ; Treatment ; Management ; Thrombosis ; Epidemiology ; Risk factors ; prevention ; bic Book Industry Communication::M Medicine
    Language: English
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