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  • Elsevier  (124)
  • Cham :Springer International Publishing :  (27)
  • Oxford University Press  (10)
  • 2020-2024  (161)
  • 1945-1949
  • 2020  (161)
  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Anatomy. ; Internal medicine. ; Cytology. ; Biochemistry. ; Neuroscience. ; Anatomy. ; Internal Medicine. ; Cell Biology. ; Biochemistry.
    Description / Table of Contents: Neurosecretion: A Historical Overview -- Neurosecretion: Hypothalamic Somata versus Neurohypophysial Terminals -- Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus -- Somato-Dendritic Secretion of Neuropeptides -- Neurosecretory Vesicles: Structure, Distribution, Release and Breakdown -- Molecular Controls on Regulated Neurotransmitter and Neurohormone Secretion -- Secretory Astrocytes -- Action Potential-Induced Ca2+ Influx for Both Acute and Sustained Insulin Secretion in Pancreatic Beta Cells -- Plasticity in the Morphology of Lactotrophs and Folliculo-Stellate Cells and Prolactin Secretion -- Neuroendocrine and Metabolic Regulation of Plasma Growth Hormone Secretory Profiles -- Role of the TWIK-Related Potassium (TREK)-1 Channels in the Regulation of Adrenocorticotropic Hormone (ACTH) Secretion from Pituitary Corticotropes -- How Do Bacterial Neurotoxins Affect Neurosecretion? -- Secretory Mechanisms in Paramecium.
    Abstract: How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state‐dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted. While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows. This is the eighth volume in the Masterclass in Neuroendocrinology series* - now a co-publication between Springer Nature and the INF (International Neuroendocrine Federation). *Volumes 1-7 published by Wiley.
    Type of Medium: Online Resource
    Pages: XIII, 307 p. 65 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030229894
    Series Statement: Masterclass in Neuroendocrinology, 8
    DDC: 612.8
    Language: English
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  • 2
    Keywords: Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Description / Table of Contents: Ch 1: Listening to All Voices: Interdisciplinary Approaches to Understanding Hearing in Aging -- Ch 2: Genetic and Molecular Aspects of the Aging Auditory System -- Ch 3: The Aging Cochlea and Auditory Nerve -- Ch 4: Age-Related Changes in the Auditory Brainstem and Inferior Colliculus -- Ch 5: Age related changes in the primate auditory cortex -- Ch 6: The Aging Auditory System: Electrophysiology -- Ch 7: Age-Related Changes in Segregation of Sound Sources -- Ch 8: Causes and Consequences of Age-Related Hearing Loss -- Ch 9: Age-Related Changes in Speech Understanding: Peripheral versus Cognitive Influences -- Ch 10: Aging, Hearing Loss, and Listening Effort: Imaging Studies of the Aging Listener -- Ch 11: Functional Consequences of Impaired Hearing in Older Adults and Implications for Intervention -- Ch 12: Emerging Clinical Translational Treatment Strategies for Age-Related Hearing Loss.
    Abstract: This volume provides contemporary discussions on new developments in aging research. It serves as an important update on the current state of research on the aging auditory system. Listening to All Voices: Interdisciplinary Approaches to Understanding Hearing in Aging Karen S. Helfer and Edward L. Bartlett Genetic and Molecular Aspects of the Aging Auditory System Shinichi Someya and Mi-Jung Kim The Aging Cochlea and Auditory Nerve Kevin K. Ohlemiller and Christopher Spankovich Age-Related Changes in the Auditory Brainstem and Inferior Colliculus Josef Syka Age-Related Changes in the Primate Auditory Cortex Gregg Recanzone The Aging Auditory System: Electrophysiology Kelly C. Harris Age-Related Changes in Segregation of Sound Sources Frederick J. Gallun and Virginia Best Causes and Consequences of Age-Related Hearing Loss Jennifer A. Deal, Nicholas S. Reed, Emily C. Pedersen, and Frank R. Lin Age-Related Changes in Speech Understanding: Peripheral versus Cognitive Influences Sandra Gordon-Salant, Maureen J. Shader, and Arthur Wingfield Aging, Hearing Loss, and Listening Effort: Imaging Studies of the Aging Listener Stefanie E. Kuchinsky and Kenneth I. Vaden, Jr. Functional Consequences of Impaired Hearing in Older Adults and Implications for Intervention Larry E. Humes, M. Kathleen Pichora-Fuller, and Louise Hickson Emerging Clinical Translational Treatment Strategies for Age-Related Hearing Loss Robert D. Frisina, Carlos J. Cruz, Tanika T. Williamson, Xiaoxia Zhu, and Bo Ding .
    Type of Medium: Online Resource
    Pages: XVII, 323 p. 62 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030493677
    Series Statement: Springer Handbook of Auditory Research, 72
    DDC: 612.8
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Evolution (Biology). ; Science History. ; Science Philosophy. ; Evolutionary Biology. ; History of Science. ; Philosophy of Science.
    Description / Table of Contents: Chapter 1: Context -- Chapter 2: A Talking Book -- Chapter 3: Setting the Stage -- Chapter 4: Neo-Darwinism, Expansion and Consolidation (1900-1980) -- Chapter 5: Criticism, Resistance, a Glimmer of Hope -- Chapter 6: Buying Time -- Chapter 7: Making Space -- Chapter 8: Conflict Resolution -- Chapter 9: Evolutionary Transitions -- Chapter 10: The Stockholm Paradigm -- Chapter 11: Putting Evolution to Work.
    Abstract: This book presents a unified evolutionary framework based on three sets of metaphors that will help to consolidate discussions on evolutionary transitions. Evolution is the unifying principle of life, making identifying ways to apply evolutionary principles to tackle existence-threatening crises such as climate change crucial. A more cohesive evolutionary framework will further the discussions in this regard and also accelerate the process itself. This book lays out a framework based on three dualistic classes of metaphors – time, space, and conflict resolution. Evolutionary transitions theory shows how metaphors can help us understand selective diversification, as Darwin described with his “tree of life”. Moreover, the recently proposed Stockholm paradigm demonstrates how metaphors can help shed light on the emergence of complex ecosystems that Darwin highlighted with his “tangled bank” metaphor. Taken together, these ideas offer proactive measures for coping with existential crises for humanity, such as climate change. The book will appeal to biologists, philosophers and historians alike.
    Type of Medium: Online Resource
    Pages: XVII, 273 p. 33 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030520861
    Series Statement: Evolutionary Biology – New Perspectives on Its Development, 2
    DDC: 576.8
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Plant genetics. ; Plant biotechnology. ; Forestry. ; Plant Genetics. ; Plant Biotechnology. ; Forestry.
    Description / Table of Contents: Introduction -- The White spruce genome -- Targeted and whole genome re-sequencing for population and evolutionary genomic inferences in Norway spruce -- Transposable elements in Spruce -- An intact, but dormant LTR retrotransposon defines a moderately-sized family in white spruce (Picea glauca) -- The DNA methylome of Norway spruce -- Epigenomics in Norway spruce -- Comparative Genomics of Spruce -- Comparative genomics with the comparisons of BACs between loblolly pine and white spruce -- Wood formation and genomic selection in white spruce, data imputation strategies -- Ecotypes in Norway spruce (“Genomics of adaptation to drought across the Central European range of Norway spruce“) -- Local adaptation in the interior spruce hybrid complex -- Genomics of secondary metabolism - Terpenoids in spruce (Evolutionary dynamics of TPS gene family in Chinese spruce) -- Lignin biosynthesis in Norway spruce as an anti-fungal defense -- Future prospects.
    Abstract: This book offers comprehensive information on the genomics of spruces (Picea spp.), naturally abundant conifer tree species that are widely distributed in the Northern Hemisphere. Due to their tremendous ecological and economic importance, the management of forest genetic resources has chiefly focused on conservation and tree improvement. A draft genome sequence of the 20-gigabase Norway spruce genome was published in the journal Nature in 2013. Continuous efforts to improve the spruce genome assembly are underway, but are hindered by the inherent characteristics of conifer genomes: high amounts of repetitive sequences (introns and transposable elements) in the genome and large gene family expansions with regards to abiotic stress, secondary metabolism and spruces' defense responses to pathogens and herbivory. This book presents the latest information on the status of genome assemblies, provides detailed insights into transposable elements and methylation patterns, and highlights the extensive genomic resources available for inferring population genomics and climate adaptation, as well as emerging genomics tools for tree improvement programs. In addition, this volume features whole-genome comparisons among conifer species, and demonstrates how functional genomics can be used to improve gene function annotations. The book closes with an outlook on emerging fields of research in spruce genomics.
    Type of Medium: Online Resource
    Pages: XIV, 218 p. 48 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030210014
    Series Statement: Compendium of Plant Genomes,
    DDC: 581.35
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human physiology. ; Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human Physiology.
    Description / Table of Contents: Successful Vaccines -- Immunogenicity and Immunodominance in Antibody Responses -- Immunogen Design -- Adjuvants -- Tools to screen vaccines -- Targeting glycans on human pathogens for vaccine design -- BnAbs and highly antigenically variable pathogens.
    Abstract: Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine. .
    Type of Medium: Online Resource
    Pages: VII, 180 p. 16 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030580049
    Series Statement: Current Topics in Microbiology and Immunology, 428
    DDC: 615
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Microbiology. ; Biotechnology. ; Evolution (Biology). ; Biomaterials. ; Nucleic acids. ; Cytology. ; Microbiology. ; Biotechnology. ; Evolutionary Biology. ; Nucleic Acid. ; Cell Biology.
    Description / Table of Contents: Reduced and Minimal Cell Factories in Bioprocesses: Towards a Streamlined Chassis -- Construction of minimal genomes and synthetic cells -- Engineering reduced-genome strains of Pseudomonas putida for product valorization -- Genome-reduced Corynebacterium glutamicum fit for biotechnological applications -- Reduction of the Saccharomyces cerevisiae genome: challenges and perspectives -- The use of in silico genome-scale models for the rational design of minimal cells -- From minimal to minimized genomes: Functional design of microbial cell factories -- Resource allocation principles and minimal cell design.
    Abstract: This book provides a comprehensive overview of the design, generation and characterization of minimal cell systems. Written by leading experts, it presents an in-depth analysis of the current issues and challenges in the field, including recent advances in the generation and characterization of reduced-genome strains generated from model organisms with relevance in biotechnology, and basic research such as Escherichia coli, Corynebacterium glutamicum and yeast. It also discusses methodologies, such as bottom-up and top-down genome minimization strategies, as well as novel analytical and experimental approaches to characterize and generate minimal cells. Lastly, it presents the latest research related to minimal cells of serveral microorganisms, e.g. Bacillus subtilis. The design of biological systems for biotechnological purposes employs strategies aimed at optimizing specific tasks. This approach is based on enhancing certain biological functions while reducing other capacities that are not required or that could be detrimental to the desired objective. A highly optimized cell factory would be expected to have only the capacity for reproduction and for performing the expected task. Such a hypothetical organism would be considered a minimal cell. At present, numerous research groups in academia and industry are exploring the theoretical and practical implications of constructing and using minimal cells and are providing valuable fundamental insights into the characteristics of minimal genomes, leading to an understanding of the essential gene set. In addition, research in this field is providing valuable information on the physiology of minimal cells and their utilization as a biological chassis to which useful biotechnological functions can be added.
    Type of Medium: Online Resource
    Pages: VII, 230 p. 35 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030318970
    DDC: 579
    Language: English
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  • 7
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Agriculture. ; Environmental monitoring. ; Computer-aided engineering. ; Bioinformatics. ; Computer simulation. ; Agriculture. ; Environmental Monitoring. ; Computer-Aided Engineering (CAD, CAE) and Design. ; Computational and Systems Biology. ; Computer Modelling.
    Description / Table of Contents: Section I - MODELLING IN WEED SCIENCE -- Chapter 1 - Mathematical models -- Chapter 2 - Decision Support Systems in Weed Science -- Chapter 3 - Optimization in DSS -- Section II - BIO-ECOLOGICAL MODELS -- Chapter 4 - Population-based models -- Chapter 5 - Weed germination and dormancy models -- Chapter 6 - Field Emergence models -- Chapter 7 - Interference/Competition models -- Chapter 8 - Herbicide resistance modelling -- Section III - ENVIRONMENTAL RISK MODELLING -- Chapter 9 - Theory and practice for environmental risk assessment of weed management systems -- Chapter 10 - Environmental risk indicators for weed management assessment: a case study of ecotoxicity risk using fuzzy logic -- Chapter 11 - DRASTIC GIS-based models: assessing the vulnerability of groundwater resources -- Section IV - WEED MANAGEMENT DECISION SUPPORT SYSTEMS: STUDY CASES -- Chapter 12 - FLORSYS model: How to use a virtual field to evaluate and design IWM strategies at different spatial and temporal scales -- Chapter 13 - Ryegrass Integrated Management (RIM)-based DSS -- Chapter 14 - CPOweeds: DSS for multispecies weed control in cereals crops -- Chapter 15 - AVENA-NET/LOLIUM-NET: DSS for Avena sterilis and Lolium rigidum control in cereal crops -- Chapter 16 - AVESUD: DSS for Avena fatua control in winter cereal crop rotations -- Chapter 17 - DSS Perspectives, Challenges and Future work.
    Abstract: Weed management Decision Support Systems (DSS) are increasingly important computer-based tools for modern agriculture. Nowadays, extensive agriculture has become highly dependent on external inputs and both economic costs, as well the negative environmental impact of agricultural activities, demands knowledge-based technology for the optimization and protection of non-renewable resources. In this context, weed management strategies should aim to maximize economic profit by preserving and enhancing agricultural systems. Although previous contributions focusing on weed biology and weed management provide valuable insight on many aspects of weed species ecology and practical guides for weed control, no attempts have been made to highlight the forthcoming importance of DSS in weed management. This book is a first attempt to integrate 'concepts and practice' providing a novel guide to the state-of-art of DSS and the future prospects which hopefully would be of interest to higher-level students, academics and professionals in related areas.
    Type of Medium: Online Resource
    Pages: XII, 342 p. 86 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030444020
    DDC: 630
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Agriculture. ; Pollution. ; Botanical chemistry. ; Plant Science. ; Agriculture. ; Pollution. ; Plant Biochemistry.
    Description / Table of Contents: In-Situ Phytoremediation of Metals -- Phytoremediation of Organic Pollutants -- Phytoremediation of Agricultural Pollutants -- Prinicples of Phytoremediation -- Rhizobacteria enhance root exudation, metal uptake and plant growth under abiotic stress -- Exploiting the Rhizosphere for Phytoremediation Enhancement -- Phytoremiediation of metals by aquatic macrophytes -- Phytoremediation using crop plants -- Phytoremediation using algae -- Impact of munitions compounds on native vegetation -- Phytoremediation of soils contaminated by hydrocarbon -- Exploitation of Rhizosphere for Phytoenhancement of HM Contaminated Industrial Soils using MYCORRHIZOREMEDIATION Technology -- Phytoremediation using Native Plants -- Phytoremediation using Aquatic Plants -- Growing Role of Biotechnology in Phytoremediation -- History of Phytoremediation -- Exploiting the Rhizosphere for Phytoremediation Enhancement -- Phytoremediation of wastewater -- Rhizosphere for Phytoremediation Enhancement.
    Abstract: This book provides in-situ phytoremediation strategies that are particularly well suited for developing nations. Its goal is to promote the use of field-tested phytoremediation methods for removing soil and water pollutants from agricultural, industrial, military, and municipal sources. These strategies include using algae and a variety of aquatic and terrestrial plants. The book subsequently discusses the use of crops and native plants for phytoremediation, and how phytoremediation efforts impact the rhizosphere. After having finished the book, readers will be able to directly adapt the strategies described here for their specific purposes. .
    Type of Medium: Online Resource
    Pages: VIII, 367 p. 38 illus., 28 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030000998
    Series Statement: Concepts and Strategies in Plant Sciences,
    DDC: 580
    Language: English
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  • 9
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Bioethics. ; Security, International. ; Security systems. ; Neuroscience. ; Bioethics. ; International Security Studies. ; Security Science and Technology.
    Description / Table of Contents: 1. Modern Neuroscience -- 2. The Chemical and Biological Non-Proliferation Regime in 2018 -- 3. Neuroethics and the Regulation of Misuse -- 4. Dual-Use Neuroscience? -- 5. The EU Human Brain Project -- 6. The US BRAIN Initiative -- 7. Global Neuroethics in Early 2019 -- 8. Japan’s BRAIN/Minds Project -- 9. China’s Brain Project -- 10. Conclusion.
    Abstract: After COVID-19 ensuring biological security will be a critical necessity. Neuroscience and the Problem of Dual Use focuses on the fact that benignly intended research in the life sciences could be misused for hostile purposes. It details the revolution that is taking place in neuroscience during this period of instability in international security, describes the new major State-funded brain research projects, and suggests ways in which hostile misuse could be prevented in coming decades.
    Type of Medium: Online Resource
    Pages: XXV, 210 p. 4 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030537906
    Series Statement: Advanced Sciences and Technologies for Security Applications,
    DDC: 612.8
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Ecology . ; Zoology. ; Conservation biology. ; Ecology. ; Zoology. ; Conservation Biology.
    Description / Table of Contents: 1. Introduction: aquatic insects in Australia’s environments -- 1.1. The background to concern -- References -- 2. Major habitats -- 2.1. Introduction -- 2.2. Ponds and lakes -- 2.3. Streams and rivers -- References -- 3. Australian inland waters -- 3.1. Introduction -- 3.2. Waterfalls -- 3.3. Subterranean aquifers -- 3.4. Rock pools -- 3.5. Mound springs -- 3.6. Lakes -- 3.7. Billabongs -- 3.8. Streams and rivers -- 3.9. Exposed riverine sediments -- References -- 4. Monitoring freshwater macroinvertebrates -- 4.1. Scope and needs for assessments -- References -- 5. Threats: the background variations in condition -- 5.1. Introduction -- 5.2. Drought -- 5.3. Flood -- References -- 6. Major imposed threats -- 6.1. Introduction -- 6.2. Water temperature -- 6.3. Sedimentation -- 6.3.1. Mining -- 6.4. Pollution -- 6.5. Salinisation -- 6.6. Exploitation -- 6.7. Electrofishing -- 6.8. Changes to riparian vegetation -- 6.8.1. Emergent vegetation -- 6.9. Alien species -- 6.9.1. Plants -- 6.9.2. Fish -- 6.9.3. Mammals -- 6.10. River regulation -- 6.11. Fire -- 6.12. Urbanisation -- 6.13. Recreation -- 6.14. Ecological traps -- 6.15. Climate change -- References -- 7. Macroinvertebrates of inland waters -- 7.1. Introduction -- 7.2. The variety of aquatic insects -- 7.3. Other macroinvertebrates -- 7.3.1. Crustaceans -- 7.3.2. Molluscs -- References -- 8. Insects of Australia’s inland waters -- 8.1. Introduction -- 8.2. Ephemeroptera -- 8.3. Odonata -- 8.4. Plecoptera -- 8.5. Hemiptera -- 8.6. Coleoptera -- 8.7. Mecoptera -- 8.8. Megaloptera -- 8.9. Neuroptera -- 8.10. Lepidoptera -- 8.11. Trichoptera -- 8.12. Diptera -- 8.12.1. Control of aquatic pest flies -- References -- 9. Australia’s flagship freshwater insects -- 9.1. Introduction -- 9.2. Selected flagship taxa -- References -- 10. Ecology and management -- 10.1. Introduction -- 10.2. Dispersal -- 10.2.1. Impacts of urban lighting -- 10.2.2. Pond colonization -- References -- 11. Conservation -- 11.1. Introduction -- 11.2. Protected areas -- 11.3. Management and restoration -- 11.4. Fish conservation -- 11.5. Education and involvement -- 11.6. Artificial water bodies -- 11.7. Temporary ponds -- 11.8. Intermittent streams -- 11.9. Stormwater retention ponds -- 11.10. Refuges -- 11.11. Woody debris -- 11.12. Riparian zones -- 11.13. Perspective and prospects -- References -- Appendix 1 -- Index.
    Abstract: The inland waters of Australia, and their largely endemic insect inhabitants, are subject to a wide and increasing variety of threats that continue to change those environments and lead to losses of insect habitats and localised taxa. Many of those changes result from human needs for water and measures to assure supply in naturally varied flood/drought regimes on which anthropogenic changes are imposed, and to which aquatic biota are increasingly susceptible. This book is a broad overview of Australian aquatic insects, the problems they face as changes to key habitats occur, and measures by which their survival may be enhanced through practical conservation. As well as summarising the current conservation interest in aquatic insects in Australia, the text draws on information and case histories from many parts of the world to augment the generally more limited information from Australian taxa and their needs, to facilitate use and perspective on conservation practice by non-specialist conservation managers, whilst also being of value to entomologists interested more directly in aquatic insect ecology and conservation .The numerous references to many taxa, regions and ecological contexts provide examples for possible emulation in Australia, and summarises many practical lessons relevant to honing effective conservation across the range from individual threatened species to the more complex protection or restoration of aquatic communities in which insects play significant functional roles.
    Type of Medium: Online Resource
    Pages: XIV, 303 p. 45 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030570088
    DDC: 577
    Language: English
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