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  • 2020  (118)
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  • 1
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Molecular genetics. ; Cancer. ; Genetics. ; Biochemistry. ; Biological transport. ; Cell membranes. ; Molecular Genetics. ; Cancer Biology. ; Genetics and Genomics. ; Biochemistry. ; Membrane Trafficking.
    Description / Table of Contents: 1. History of sialic acids, gangliosides and GM3 -- 2. Synthesis of GM3 -- 3. Molecular localization of GM3 in cells -- 4. Basic function of GM3 as an interacting molecule -- 5. GD3 mimetics with a neurite forming capacity -- 6. GM3 as a pathogenic infection receptor -- 7. GM3 and related gangliosides prevent inflammation and atherosclerosis -- 8. GM3 has an anti-tumor capacity -- 9. GM3 suppresses tumor angiogenesis -- 10. Interaction between EGFR and GM3 -- 11. Membrane ganglioside-specific neuraminidase 3 (NEU3) regulates GM3 signaling -- 12. Regulation of GM3-mediated EGFR signaling by NEU3 sialidase -- 13. VEGFR-GM3 interaction in angiogenesis -- 14. GM3, competing with GM1, interaction with urokinase plasminogen activator receptor (uPAR) in endothelial caveolar-lipid rafts inhibits angiogenesis -- 15. GM3 interacts with TGFβ Rs in the epithelial-mesenchymal transition (EMT) during posterior capsular opacification (PCO) formation -- 16. Galectin-1 promotes tumor growth and escapes immune surveillance -- 17. GM3-HGFR, FGFR and PDGFR cancer cell behavior, and IGF-1R in diabetic wound healing -- 18. GM3, caveolin-1 and insulin receptor in insulin resistance -- 19. GM3 suppresses arthritis -- 20. GM3 protects cochlear hair cells and hearing from corti degeneration -- 21. GM3 increases osteoclast differentiation via direct GM3 cooperation with RANKL and IGF-1 -- 22. GM3 in leukemic cells into terminal differentiation -- 23. α2,3-Sialyllactose (3SL) or α2,6-sialyllactose (6SL) of GM3 glycan in innate immunity. .
    Abstract: This book reviews recent progress in understanding of the signaling and biochemistry of GM3 ganglioside in eukaryotic cells. GM3 is the simplest of the gangliosides and the precursor of other gangliosides. It is expressed in the outer leaflet of plasma cell membranes and has roles in the recognition, interaction, binding, adhesion, and motility of cells. In addition, GM3 has been documented to have functional roles in cell migration, proliferation, senescence, and apoptosis. The full range of topics of interest are addressed in the book. The early chapters discuss the synthesis of GM3, its molecular localization in cells, and its basic function as an interacting molecule. The ways in which GM3 exerts its effects via various growth factor receptors are fully explored. Current knowledge of the part played by GM3 in health and disease is discussed in depth. For example, its roles in preventing inflammation, inhibiting tumor angiogenesis and tumor growth, and suppressing arthritis are highlighted, and attention drawn to the significance of GM3 as a driver of impaired wound healing in diabetics. The book will be of interest to all who want a comprehensive update on research in this field.
    Type of Medium: Online Resource
    Pages: VII, 138 p. 32 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811556524
    DDC: 572.8
    Language: English
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  • 2
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Molecular genetics. ; Cancer. ; Genetics. ; Biochemistry. ; Biological transport. ; Cell membranes. ; Molecular Genetics. ; Cancer Biology. ; Genetics and Genomics. ; Biochemistry. ; Membrane Trafficking.
    Description / Table of Contents: Preface: Carbohydrates- the third life chain -- 1. Glycosylation -- 2. N-Glycan and O-glycan glycosylation in eukaryotes -- 3. Sialyltransferase, sialylation and sulfoylation -- 4. Congenital disorders of glycosylation (CDG) of N-glycoprotein -- 5. Neuraminic acids/sialic acids (N-acetyl- and N-glycolylneuraminic acid) -- 6. Biosynthesis of sialic acid -- 7. Neu5Gc (N-glycolylneuraminic acid) -- 8. Gangliosides -- 9. Gangliosides and tumor-associated ganglioside (TAG) modulate receptor-tyrosine kinases (RTKs) -- 10. Sialic acids and TAGs of tumor cells to escape immunesurveillance and immuneediting -- 11. Tumor characteristics in tumor related carbohydrates.
    Abstract: This book presents the latest knowledge and the most recent research results in the field of ganglioside biochemistry. The early chapters cover all relevant background on sialic acids and their biosynthesis, on N-glycolylneuraminic acid (Neu5Gc), which cannot be synthesized by humans, and on general aspects of ganglioside research. Ganglioside adsorption, disorders of ganglioside degradation, and the regulation of gangliosides are thoroughly discussed. A major focus of the book is the role of gangliosides in cancer. Here, the discussion encompasses, for example, the biological importance, antigenicity, and immunological actions of tumor-associated gangliosides (TAGs), the significance of different glycolipids and gangliosides as TAGs, and emerging anti-cancer vaccine strategies. The ability of sialic acids and TAGs of tumor cells to escape immunosurveillance and immunoediting also receives detailed attention. The significance of sialic acids in regulation of the complement system is explained, and the closing chapter focuses especially on the role of sialyl T antigen in cancer. The book will be of value for all who are interested in functional glycobiology and glycomic studies.
    Type of Medium: Online Resource
    Pages: XVI, 214 p. 57 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811558153
    DDC: 572.8
    Language: English
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  • 3
    Keywords: Physical geography. ; Climatology. ; Water. ; Hydrology. ; Engineering geology. ; Oceanography. ; Earth System Sciences. ; Climate Sciences. ; Water. ; Geoengineering. ; Ocean Sciences.
    Description / Table of Contents: 1. A 14-year Multi-sites and High-frequency Monitoring of Salinity in the Tidal Garonne River (S-W France) Reveals Marked Inter-annual Variability In Marine Intrusion -- 2. Study on Salinity Intrusion and Mixing Types in a Conceptual Estuary using 3-D Hydrodynamic Simulation: Effects of Length, Width, Depth, and Bathymetry -- 3. Response of Salinity Intrusion to the Fictitious Blockade of the North Branch in the Yangtze Estuary, China -- 4. Influence of the Salinity Intrusion on Island Water Source Safety: A Case Study of the Chongming Island, China -- 5. Law of salt tide intrusion of the Qiantang Estuary and its numerical simulation -- 6. Seasonal salinity variations in a coastal wetland induced by complex interactions between sea, river and evapoconcentration processes -- 7. Water Quality Mitigation Scenarios for Burullus Coastal Lake, Egypt -- 8. Research on the Setting Condition of Tailrace Surge Chambers for Seawater Pumped-storage Power Stations with Long Tailrace Tunnels.
    Abstract: This book is a collection of extended papers based on presentations given during the ICEC 2018 conference, held in Caen, France, in August 2018. It explores both the limitations and advantages of current models, and highlights the latest developments concerning new numerical schemes, high-performance computing, multi-physics and multi-scale methods, and better interaction with field or scale model data. Accordingly, it addresses the interests of practitioners, stakeholders, researchers, and engineers active in this field. .
    Type of Medium: Online Resource
    Pages: XX, 843 p. 494 illus., 402 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811520815
    Series Statement: Springer Water,
    DDC: 550
    Language: English
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  • 4
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Neuropsychology. ; Neuroscience. ; Neuropsychology.
    Description / Table of Contents: Part 1. Brain network concepts -- Chapter 1. Task MRI-based functional brain network of anxiety -- Chapter 2. Phenotype network and brain structural covariance network of anxiety -- Chapter 3. linear/nonlinear micro-and-macro state EEG-based functional networks for anxiety -- Chapter 4. White matter-based structural brain network of anxiety -- Chapter 5. Resting state abnormalities in anxiety disorders and spatiotemporal psychopathology -- Part 2. Neurobiological Aspects -- Chapter 6. Gene-environmental interactions and role of epigenetics in anxiety disorders -- Chapter 7. The role of the oxytocin system in anxiety disorders -- Chapter 8. Translational studies in the complex roles of neurotransmitter systems in anxiety and anxiety disorders -- Chapter 9. The role of early life stress in HPA axis dysfunction in anxiety disorders -- Chapter 10. Immune-kynurenine pathways and the gut-microbiota-brain axis in anxiety disorders -- Chapter 11. Experimental anxiety model for anxiety disorders: relevance to drug discovery -- Part 3. Diagnostic and clinical Issues -- Chapter 12. Anxiety disorders in DSM-5: changes, controversies, and future directions -- Chapter 13. Biological markers to differentiate the type of anxiety disorders -- Chapter 14. Comorbid anxiety and depression: clinical and conceptual consideration, transdiagnostic treatment -- Chapter 15. Anxiety disorders and medical comorbidity: treatment implications -- Part 4. Therapeutic Issues -- Chapter 16. Biofeedback and Neurofeedback for Anxiety Disorders: A Quantitative and Qualitative Systematic Review -- Chapter 17. Cognitive Behavioral Therapy, Mindfulness-Based Cognitive Therapy and Acceptance Commitment Therapy for Anxiety Disorders: Integrating Traditional with Digital Treatment Approaches -- Chapter 18. Neurostimulation in anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder -- Chapter 19. Current and novel psychopharmacological drugs for anxiety disorders -- Chapter 20. Role of benzodiazepines in anxiety disorders -- Chapter 21. Virtual Reality for Anxiety Disorders: Rethinking a Field in Expansion -- Chapter 22. Current research on complementary and alternative medicine (CAM) in the treatments of anxiety disorders: evidence based review -- Chapter 23. Contemporary Psychodynamic Approaches to Treating Anxiety: Theory, Research, and Practice -- Chapter 24. Well-being therapy in anxiety disorders -- Part 5. Anxiety and precision psychiatry -- Chapter 25. Personalized clinical approaches to anxiety disorders -- Chapter 26. The role of hormonal and reproductive status in the treatment of anxiety disorders in women -- Chapter 27. Risk factors and prevention strategies for anxiety disorders in childhood and adolescence -- Chapter 28. Anxiety disorders in the elderly.
    Abstract: This book reviews all important aspects of anxiety disorders with the aim of shedding new light on these disorders through combined understanding of traditional and novel paradigms. The book is divided into five sections, the first of which reinterprets anxiety from a network science perspective, examining the altered topological properties of brain networks in anxiety disorders. The second section discusses recent advances in understanding of the neurobiology of anxiety disorders, covering, for example, gene-environmental interactions and the roles of neurotransmitter systems and the oxytocin system. A wide range of diagnostic and clinical issues in anxiety disorders are then addressed, before turning attention to contemporary treatment approaches in the context of novel bio-psychosocial-behavioral models, including bio- and neurofeedback, cognitive behavioral therapy, neurostimulation, virtual reality exposure therapy, pharmacological interventions, psychodynamic therapy, and CAM options. The final section is devoted to precision psychiatry in anxiety disorders, an increasingly important area as we move toward personalized treatment. Anxiety Disorders will be of interest for all researchers and clinicians in the field.
    Type of Medium: Online Resource
    Pages: VII, 576 p. 32 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789813297050
    Series Statement: Advances in Experimental Medicine and Biology, 1191
    DDC: 612.8
    Language: English
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  • 5
    Keywords: Nervous system Surgery. ; Orthopedic surgery. ; Neurosurgery. ; Surgical Orthopedics.
    Description / Table of Contents: 1. Special issue of endoscopic spine surgery -- (1) Paradigm shifting of spinal endoscopic approach -- (2) Nomenclature of endoscopic surgery -- (3) Learning curve of endoscopic lumbar discectomy -- 2. Lumbar central stenosis -- (1) Full endoscopic posterior approach: in and out -- (2) Full endoscopic posterior approach: out and in -- (3) Biportal endoscopic approach -- 3. Lumbar foraminal stenosis -- (1) Full endoscopic contralateral approach -- (2) Full endoscopic transforaminal approach -- (3) Full endoscopic paraspinal approach -- (4) Biportal endoscopic contralateral approach -- (5) Biportal endoscopic paraspinal approach -- 4. Lumbar disc herniation -- (1) Full endoscopic approach with foraminoplasty -- (2) Full endoscopic transpedicular approach -- (3) Biportal endoscopic approach -- 5. Endoscopic lumbar interbody fusion -- (1) Endoscopic OLIF -- (2) Endoscopic LIF uniportal -- (3) Endoscopic LIF biportal.
    Abstract: This book is a superbly illustrated guide to the latest endoscopic approaches employed in surgery to the lumbar spine. In the past, spinal endoscopic surgeries have been performed mainly in the treatment of lumbar disc herniation, but indications have now expanded owing to breakthroughs in surgical methods and instruments. Furthermore, in addition to the traditional percutaneous transforaminal approach, various other approaches are now feasible, including the posterior, paraspinal, transpedicular, and contralateral. This book describes and illustrates the full array of approaches in indications including lumbar central stenosis, lumbar foraminal stenosis, and lumbar disc herniation. Detailed guidance is also provided on endoscopic lumbar interbody fusion, covering the oblique, uniportal, and biportal approaches. Supplementary surgical videos further facilitate understanding and execution of the described procedures. Written by expert spinal endoscopy surgeons with extensive practical experience and a record of academic achievement, the book will be an ideal aid for spine surgeons at all levels of experience.
    Type of Medium: Online Resource
    Pages: XVIII, 172 p. 162 illus., 137 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811582530
    DDC: 617.48
    Language: English
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  • 6
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Molecular genetics. ; Cancer. ; Genetics. ; Biochemistry. ; Biological transport. ; Cell membranes. ; Molecular Genetics. ; Cancer Biology. ; Genetics and Genomics. ; Biochemistry. ; Membrane Trafficking.
    Description / Table of Contents: 1. Glycosphingolipids (GSLs) -- 2. Mammal GSL synthesis via ER and Golgi network -- 3. The GSL dependent signaling -- 4. Viral protein interaction with host cells GSLs -- 5. Bacterial toxin protein interaction with host cells GSL -- 6. GSL signaling regulation.
    Abstract: This book presents the latest knowledge and the most recent research results on glycosphingolipid (GSL)-mediated signaling. GSLs are important constituents of the plasma membrane that exert their distinct functions through binding to certain functional proteins. They play a role in various human diseases and also function as human alloantigens. Cellular GSLs are associated with many biological functions such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell–cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein–carbohydrate or carbohydrate–carbohydrate interactions. This book opens by providing the key background on GSL glycan–receptor interactions and mammalian GSL synthesis. Up-to-date information is then presented on all aspects of GSL-dependent signaling. Viral protein and bacterial toxin protein interactions with host cell GSLs are examined in depth, and the concluding chapter is devoted to signaling regulation. The book should assist in the further development of new strategies against emerging infectious agents and intractable diseases.
    Type of Medium: Online Resource
    Pages: XVII, 181 p. 30 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811558078
    DDC: 572.8
    Language: English
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  • 7
    Monograph available for loan
    Monograph available for loan
    Cambridge, United Kingdom : Cambridge University Press
    Call number: IASS 20.95351
    Type of Medium: Monograph available for loan
    Pages: xxii, 326 Seiten
    ISBN: 9781108747301 , 9781108489515
    Series Statement: Earth system governance
    Language: English
    Branch Library: RIFS Library
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  • 8
    Publication Date: 2024-04-30
    Description: Novel species of fungi described in this study include those from various countries as follows: Australia, Austroboletus asper on soil, Cylindromonium alloxyli on leaves of Alloxylon pinnatum, Davidhawksworthia quintiniae on leaves of Quintinia sieberi, Exophiala prostantherae on leaves of Prostanthera sp., Lactifluus lactiglaucus on soil, Linteromyces quintiniae (incl. Linteromyces gen. nov.) on leaves of Quintinia sieberi, Lophotrichus medusoides from stem tissue of Citrus garrawayi, Mycena pulchra on soil, Neocalonectria tristaniopsidis (incl. Neocalonectria gen. nov.) and Xyladictyochaeta tristaniopsidis on leaves of Tristaniopsis collina, Parasarocladium tasmanniae on leaves of Tasmannia insipida, Phytophthora aquae-cooljarloo from pond water, Serendipita whamiae as endophyte from roots of Eriochilus cucullatus, Veloboletus limbatus (incl. Veloboletus gen. nov.) on soil. Austria, Cortinarius glaucoelotus on soil. Bulgaria, Suhomyces rilaensis from the gut of Bolitophagus interruptus found on a Polyporus sp. Canada, Cantharellus betularum among leaf litter of Betula, Penicillium saanichii from house dust. Chile, Circinella lampensis on soil, Exophiala embothrii from rhizosphere of Embothrium coccineum. China, Colletotrichum cycadis on leaves of Cycas revoluta. Croatia, Phialocephala melitaea on fallen branch of Pinus halepensis. Czech Republic, Geoglossum jirinae on soil, Pyrenochaetopsis rajhradensis from dead wood of Buxus sempervirens. Dominican Republic, Amanita domingensis on litter of deciduous wood, Melanoleuca dominicana on forest litter. France, Crinipellis nigrolamellata (Martinique) on leaves of Pisonia fragrans, Talaromyces pulveris from bore dust of Xestobium rufovillosum infesting floorboards. French Guiana, Hypoxylon hepaticolor on dead corticated branch. Great Britain, Inocybe ionolepis on soil. India, Cortinarius indopurpurascens among leaf litter of Quercus leucotrichophora. Iran, Pseudopyricularia javanii on infected leaves of Cyperus sp., Xenomonodictys iranica (incl. Xenomonodictys gen. nov.) on wood of Fagus orientalis. Italy, Penicillium vallebormidaense from compost. Namibia, Alternaria mirabibensis on plant litter, Curvularia moringae and Moringomyces phantasmae (incl. Moringomyces gen. nov.) on leaves and flowers of Moringa ovalifolia, Gobabebomyces vachelliae (incl. Gobabebomyces gen. nov.) on leaves of Vachellia erioloba, Preussia procaviae on dung of Procavia capensis. Pakistan, Russula shawarensis from soil on forest floor. Russia, Cyberlindnera dauci from Daucus carota. South Africa, Acremonium behniae on leaves of Behnia reticulata, Dothiora aloidendri and Hantamomyces aloidendri (incl. Hantamomyces gen. nov.) on leaves of Aloidendron dichotomum, Endoconidioma euphorbiae on leaves of Euphorbia mauritanica, Eucasphaeria proteae on leaves of Protea neriifolia, Exophiala mali from inner fruit tissue of Malus sp., Graminopassalora geissorhizae on leaves of Geissorhiza splendidissima, Neocamarosporium leipoldtiae on leaves of Leipoldtia schultzii, Neocladosporium osteospermi on leaf spots of Osteospermum moniliferum, Neometulocladosporiella seifertii on leaves of Combretum caffrum, Paramyrothecium pituitipietianum on stems of Grielum humifusum, Phytopythium paucipapillatum from roots of Vitis sp., Stemphylium carpobroti and Verrucocladosporium carpobroti on leaves of Carpobrotus quadrifolius, Suttonomyces cephalophylli on leaves of Cephalophyllum pilansii. Sweden, Coprinopsis rubra on cow dung, Elaphomyces nemoreus from deciduous woodlands. Spain, Polyscytalum pini-canariensis on needles of Pinus canariensis, Pseudosubramaniomyces septatus from stream sediment, Tuber lusitanicum on soil under Quercus suber. Thailand, Tolypocladium flavonigrum on Elaphomyces sp. USA, Chaetothyrina spondiadis on fruits of Spondias mombin, Gymnascella minnisii from bat guano, Juncomyces patwiniorum on culms of Juncus effusus, Moelleriella puertoricoensis on scale insect, Neodothiora populina (incl. Neodothiora gen. nov.) on stem cankers of Populus tremuloides, Pseudogymnoascus palmeri from cave sediment. Vietnam, Cyphellophora vietnamensis on leaf litter, Tylopilus subotsuensis on soil in montane evergreen broadleaf forest. Morphological and culture characteristics are supported by DNA barcodes.
    Keywords: Ecology ; Evolution ; Behavior and Systematics ; ITS nrDNA barcodes ; LSU ; new taxa ; systematics
    Repository Name: National Museum of Natural History, Netherlands
    Type: info:eu-repo/semantics/article
    Format: application/pdf
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  • 9
    Publication Date: 2023-02-08
    Description: A Gram-negative, aerobic bacterium, designated as SH-1 T , was isolated from the gut content of a whiteleg shrimp, Litopenaeus vannamei collected in a shrimp farm in South Korea. The bacterial cells were ovoid rod-shaped, non-motile, oxidase-positive and catalase-negative. Growth was observed at 20–35 °C (optimum, 30 °C), pH 5.0–9.5 (pH 8.5) and in the presence of 0–6 % (w/v) NaCl (2–3 %). The major polar lipids were phosphatidylglycerol, phosphatidylinositolmannoside, unidentified aminolipid and two unidentified lipids. The G+C content was 66.1 mol% and the predominant respiratory quinone was Q-10. Phylogenetic analysis based on the 16S rRNA gene sequences showed that strain SH-1 T was placed in a distinct clade with Primorskyibacter marinus PX7 T (96.97 % sequence similarity), Pontibaca methylaminivorans DSM 21219 T (96.03 %) and Pelagivirga sediminicola BH-SD19 T (95.02 %) in the family Rhodobacteraceae and distantly related with them to be a new genus. The digital DNA–DNA hybridization (dDDH), average nucleotide identity (ANI) and average amino acid identity (AAI) values calculated from whole-genome-sequence comparison between the SH-1 T and the close species were in the ranges of 19.0–19.8, 73.8–74.9 and 64.1–65.9 %, respectively. Based on the polyphasic analysis presented in this study, we suggest that strain SH-1 T represents a novel genus and species in the family Rhodobacteraceae , for which the name Pukyongiella litopenaei gen. nov., sp. nov. is proposed. The type strain of Pukyongiella litopenaei is SH-1 T (=KCTC 62276 T =MCCC 1K04072 T ).
    Type: Article , PeerReviewed
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  • 10
    Publication Date: 2023-02-08
    Description: The desiccation tolerance of the intertidal seagrass Zostera japonica has been demonstrated in a number of studies; however, the factors limiting expansion of intertidal seagrass species into subtidal zones remain controversial. We transplanted Z. japonica shoots from the intermediate intertidal zone into the plots with and without Z. marina shoots in both the lower intertidal and shallow subtidal zones to investigate the factors controlling Z. japonica growth in these zones. Daily photon flux density at the Z. japonica canopy level was attenuated by both water depth and coexisting Z. marina shoots but more strongly by Z. marina shoots than water depth in the transplant plots. The shoot density and biomass of Z. japonica transplants were significantly lower in transplant plots in the subtidal zone than in the lower intertidal zone. Although the photon flux density was significantly lower in transplant plots containing Z. marina shoots, the growth of Z. japonica transplants did not differ significantly between plots with and those without Z. marina shoots. Z. japonica transplants exhibited photoacclimatory responses such as increased shoot height and chlorophyll content under the lower-light conditions, offsetting the reduced light availability so that no significant differences in transplant growth occurred between plots with and those without Z. marina shoots. As the growth of Z. japonica transplants decreased significantly in the subtidal zone, the interactive effects of environmental stresses associated with tidal inundation and reduced light availability may restrict penetration of the intertidal seagrass Z. japonica into the subtidal zone. The persistence of high photosynthetic performance after air exposure and a regular arrangement of the densely overlapped leaves atop wet sediments may be desiccation tolerance mechanisms for Z. japonica in the intertidal zone.
    Type: Article , PeerReviewed
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