Publication Date:
2017-03-29
Description:
Depleting Mycobacterium tuberculosis of the transcription termination factor Rho causes pervasive transcription and rapid death Nature Communications, Published online: 28 March 2017; doi:10.1038/ncomms14731 The transcription termination factor Rho is essential for growth in some bacteria but not in others. Here, Botella et al . show that Rho inactivation causes extensive pervasive transcription and loss of viability of the pathogen Mycobacterium tuberculosis both in vitro and in a mouse model of infection.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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