ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Springer Nature  (14)
  • American Meteorological Society  (6)
  • Copernicus  (4)
  • Seismological Society of America (SSA)  (4)
  • 2015-2019  (28)
  • 2000-2004
  • 1975-1979
  • 2016  (28)
Collection
Publisher
Years
  • 2015-2019  (28)
  • 2000-2004
  • 1975-1979
Year
  • 1
    facet.materialart.
    Unknown
    Comparisons between VS30 and Spectral Response for 30 Sites in Newcastle, Australia, from Collocated Seismic Cone Penetrometer, Active- and Passive-Source VS Data (2016)
    Seismological Society of America (SSA)
    Details
    Publication Date: 2016-07-26
    Description: Although the time-averaged shear-wave velocity down to 30 m depth ( V S 30 ) can be a proxy for estimating earthquake ground-motion amplification, significant controversy exists about its limitations when used as a single parameter for the prediction of amplification. To examine this question in absence of relevant strong-motion records, we use a range of different methods to measure the shear-wave velocity profiles and the resulting theoretical site amplification factors (AFs) for 30 sites in the Newcastle area, Australia, in a series of blind comparison studies. The multimethod approach used here combines past seismic cone penetrometer and spectral analysis of surface-wave data, with newly acquired horizontal-to-vertical spectral ratio, passive-source surface-wave spatial autocorrelation (SPAC), refraction microtremor (ReMi), and multichannel analysis of surface-wave data. The various measurement techniques predicted a range of different AFs. The SPAC and ReMi techniques have the smallest overall deviation from the median AF for the majority of sites. We show that V S 30 can be related to spectral response above a period T of 0.5 s but not necessarily with the maximum amplification according to the modeling done based on the measured shear-wave velocity profiles. Both V S 30 and AF values are influenced by the velocity ratio between bedrock and overlying sediments and the presence of surficial thin low-velocity layers (〈2 m thick and 〈150 m/s), but the velocity ratio is what mostly affects the AF. At 0.2〈 T 〈0.4 s, the AFs are largely controlled by the surficial geology of a particular site. AF maxima are the highest in the hard classes, which is the inverse of the findings used in the Australian Building Code. Only for T 〉0.5 s do the amplification curves consistently show higher values for soft site classes and lower for hard classes.
    Print ISSN: 0037-1106
    Electronic ISSN: 1943-3573
    Topics: Geosciences , Physics
    Published by Seismological Society of America (SSA)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 2
    facet.materialart.
    Unknown
    Seismic Imaging beneath an InSAR Anomaly in Eastern Washington State: Shallow Faulting Associated with an Earthquake Swarm in a Low-Hazard Area (2016)
    Seismological Society of America (SSA)
    Details
    Publication Date: 2016-07-26
    Description: In 2001, a rare swarm of small, shallow earthquakes beneath the city of Spokane, Washington, caused ground shaking as well as audible booms over a five-month period. Subsequent Interferometric Synthetic Aperture Radar (InSAR) data analysis revealed an area of surface uplift in the vicinity of the earthquake swarm. To investigate the potential faults that may have caused both the earthquakes and the topographic uplift, we collected ~3 km of high-resolution seismic-reflection profiles to image the upper-source region of the swarm. The two profiles reveal a complex deformational pattern within Quaternary alluvial, fluvial, and flood deposits, underlain by Tertiary basalts and basin sediments. At least 100 m of arching on a basalt surface in the upper 500 m is interpreted from both the seismic profiles and magnetic modeling. Two west-dipping faults deform Quaternary sediments and project to the surface near the location of the Spokane fault defined from modeling of the InSAR data.
    Print ISSN: 0037-1106
    Electronic ISSN: 1943-3573
    Topics: Geosciences , Physics
    Published by Seismological Society of America (SSA)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 3
    facet.materialart.
    Unknown
    Lasting mantle scars lead to perennial plate tectonics (2016)
    Springer Nature
    Details
    Publication Date: 2016-06-12
    Description: Article The causes of intraplate deformation remain poorly constrained. Heron et al . use numerical models to show that ancient plate tectonic processes produce mantle lithosphere structures that may be reactivated to generate intraplate deformation. Nature Communications doi: 10.1038/ncomms11834 Authors: Philip J. Heron, Russell N. Pysklywec, Randell Stephenson
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
    Published by Springer Nature
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 4
    facet.materialart.
    Unknown
    Irinotecan-induced toxicity pharmacogenetics: an umbrella review of systematic reviews and meta-analyses (2016)
    Springer Nature
    Details
    Publication Date: 2016-08-09
    Print ISSN: 1470-269X
    Electronic ISSN: 1473-1150
    Topics: Chemistry and Pharmacology
    Published by Springer Nature
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 5
    facet.materialart.
    Unknown
    An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination (2016)
    Springer Nature
    Details
    Publication Date: 2016-04-28
    Description: Article Chondroitin sulfate proteoglycans (CSPGs) secreted by astrocytes are known to inhibit OPC differentiation and remyelination. Here, the authors identify a novel CSPG synthesis inhibitor and find it can rescue OPC differentiation in vitro and accelerate remyelination in mice following focal demyelination. Nature Communications doi: 10.1038/ncomms11312 Authors: Michael B. Keough, James A. Rogers, Ping Zhang, Samuel K. Jensen, Erin L. Stephenson, Tieyu Chen, Mitchel G. Hurlbert, Lorraine W. Lau, Khalil S. Rawji, Jason R. Plemel, Marcus Koch, Chang-Chun Ling, V. Wee Yong
    Electronic ISSN: 2041-1723
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics
    Published by Springer Nature
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 6
    facet.materialart.
    Unknown
    Preliminary Assessment of a Previously Unknown Fault Zone beneath the Daytona Beach Sand Blow Cluster near Marianna, Arkansas (2016)
    Seismological Society of America (SSA)
    Details
    Publication Date: 2016-11-04
    Description: We collected new high-resolution P -wave seismic-reflection data to explore for possible faults beneath a roughly linear cluster of early to mid-Holocene earthquake-induced sand blows to the south of Marianna, Arkansas. The Daytona Beach sand blow deposits are located in east-central Arkansas about 75 km southwest of Memphis, Tennessee, and about 80 km south of the southwestern end of the New Madrid seismic zone (NMSZ). Previous studies of these sand blows indicate that they were produced between 10,500 and 5350 yr B.P. (before A.D. 1950). The sand blows are large and similar in size to those in the heart of the NMSZ produced by the 1811–1812 earthquakes. The seismic-reflection profiles reveal a previously unknown zone of near-vertical faults imaged in the 100–1100-m depth range that are approximately coincident with a cluster of earthquake-induced sand blows and a near-linear surface lineament composed of air photo tonal anomalies. These interpreted faults are expressed as vertical discontinuities with the largest displacement fault showing about 40 m of west-side-up displacement at the top of the Paleozoic section at about 1100 m depth. There are about 20 m of folding on reflections within the Eocene strata at 400 m depth. Increasing fault displacement with depth suggests long-term recurrent faulting. The imaged faults within the vicinity of the numerous sand blow features could be a causative earthquake source, although it does not rule out the possibility of other seismic sources nearby. These newly located faults add to a growing list of potentially active Pleistocene–Holocene faults discovered over the last two decades that are within the Mississippi embayment region but outside of the historical NMSZ.
    Print ISSN: 0895-0695
    Electronic ISSN: 1938-2057
    Topics: Geosciences
    Published by Seismological Society of America (SSA)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 7
    facet.materialart.
    Unknown
    A basal ganglia circuit for evaluating action outcomes (2016)
    Springer Nature
    In: Nature
    Details
    Publication Date: 2016-11-10
    Description: A basal ganglia circuit for evaluating action outcomes Nature 539, 7628 (2016). doi:10.1038/nature19845 Authors: Marcus Stephenson-Jones, Kai Yu, Sandra Ahrens, Jason M. Tucciarone, Aile N. van Huijstee, Luis A. Mejia, Mario A. Penzo, Lung-Hao Tai, Linda Wilbrecht & Bo Li The basal ganglia, a group of subcortical nuclei, play a crucial role in decision-making by selecting actions and evaluating their outcomes. While much is known about the function of the basal ganglia circuitry in selection, how these nuclei contribute to outcome evaluation is less clear. Here we show that neurons in the habenula-projecting globus pallidus (GPh) in mice are essential for evaluating action outcomes and are regulated by a specific set of inputs from the basal ganglia. We find in a classical conditioning task that individual mouse GPh neurons bidirectionally encode whether an outcome is better or worse than expected. Mimicking these evaluation signals with optogenetic inhibition or excitation is sufficient to reinforce or discourage actions in a decision-making task. Moreover, cell-type-specific synaptic manipulations reveal that the inhibitory and excitatory inputs to the GPh are necessary for mice to appropriately evaluate positive and negative feedback, respectively. Finally, using rabies-virus-assisted monosynaptic tracing, we show that the GPh is embedded in a basal ganglia circuit wherein it receives inhibitory input from both striosomal and matrix compartments of the striatum, and excitatory input from the ‘limbic’ regions of the subthalamic nucleus. Our results provide evidence that information about the selection and evaluation of actions is channelled through distinct sets of basal ganglia circuits, with the GPh representing a key locus in which information of opposing valence is integrated to determine whether action outcomes are better or worse than expected.
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Springer Nature
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 8
    facet.materialart.
    Unknown
    Cultural innovation and megafauna interaction in the early settlement of arid Australia (2016)
    Springer Nature
    In: Nature
    Details
    Publication Date: 2016-11-10
    Description: Cultural innovation and megafauna interaction in the early settlement of arid Australia Nature 539, 7628 (2016). doi:10.1038/nature20125 Authors: Giles Hamm, Peter Mitchell, Lee J. Arnold, Gavin J. Prideaux, Daniele Questiaux, Nigel A. Spooner, Vladimir A. Levchenko, Elizabeth C. Foley, Trevor H. Worthy, Birgitta Stephenson, Vincent Coulthard, Clifford Coulthard, Sophia Wilton & Duncan Johnston Elucidating the material culture of early people in arid Australia and the nature of their environmental interactions is essential for understanding the adaptability of populations and the potential causes of megafaunal extinctions 50–40 thousand years ago (ka). Humans colonized the continent by 50 ka, but an apparent lack of cultural innovations compared to people in Europe and Africa has been deemed a barrier to early settlement in the extensive arid zone. Here we present evidence from Warratyi rock shelter in the southern interior that shows that humans occupied arid Australia by around 49 ka, 10 thousand years (kyr) earlier than previously reported. The site preserves the only reliably dated, stratified evidence of extinct Australian megafauna, including the giant marsupial Diprotodon optatum, alongside artefacts more than 46 kyr old. We also report on the earliest-known use of ochre in Australia and Southeast Asia (at or before 49–46 ka), gypsum pigment (40–33 ka), bone tools (40–38 ka), hafted tools (38–35 ka), and backed artefacts (30–24 ka), each up to 10 kyr older than any other known occurrence. Thus, our evidence shows that people not only settled in the arid interior within a few millennia of entering the continent, but also developed key technologies much earlier than previously recorded for Australia and Southeast Asia.
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Springer Nature
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 9
    facet.materialart.
    Unknown
    Continuity of the Reelfoot Fault across the Cottonwood Grove and Ridgely Faults of the New Madrid Seismic Zone (2016)
    Seismological Society of America (SSA)
    Details
    Publication Date: 2016-12-02
    Description: Previous investigators have argued that the northwest-striking Reelfoot fault of northwest Tennessee and southeastern Missouri is segmented. One segment boundary is at the intersection of the northeast-striking Cottonwood Grove and Ridgely strike-slip faults with the Reelfoot fault. We use seismic reflection and geologic mapping to locate and determine the history of the Reelfoot South fault across this boundary zone. One reflection profile revealed a southwest-dipping (81°) Reelfoot South reverse fault that displaces the top of the Paleozoic 65 m, Cretaceous 40 m, Paleocene 31 m, Eocene Wilcox Group 20 m, and Eocene Memphis Sand 16 m. A second reflection profile reveals a north-dipping (84°) reverse fault 4.3 km south of the Reelfoot South fault, which defines the southwest margin of the Tiptonville dome. A geologic profile of the base of the ~3.1 Ma Upland complex (Mississippi River terrace alluvium) within the Mississippi River bluffs reveals ~6 m of displacement across the Reelfoot South fault. Similarly, Quaternary stream terrace distribution suggests ~6 m of Reelfoot South hanging-wall (Tiptonville dome) uplift that is probably Holocene. Fault strike trends show the Reelfoot fault and its hanging-wall Tiptonville dome are not laterally offset across the Cottonwood Grove and Ridgely faults. The Reelfoot South fault northwest and southeast of the Cottonwood Grove and Ridgely faults has very similar vertical displacement on common stratigraphic marker horizons in the upper 900 m. These data indicate the Reelfoot fault/Tiptonville dome has acted as one continuous fault zone across the Cottonwood Grove and Ridgely faults since Late Cretaceous.
    Print ISSN: 0037-1106
    Electronic ISSN: 1943-3573
    Topics: Geosciences , Physics
    Published by Seismological Society of America (SSA)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 10
    facet.materialart.
    Unknown
    Ad26/MVA therapeutic vaccination with TLR7 stimulation in SIV-infected rhesus monkeys (2016)
    Springer Nature
    In: Nature
    Details
    Publication Date: 2016-12-08
    Description: Ad26/MVA therapeutic vaccination with TLR7 stimulation in SIV-infected rhesus monkeys Nature 540, 7632 (2016). doi:10.1038/nature20583 Authors: Erica N. Borducchi, Crystal Cabral, Kathryn E. Stephenson, Jinyan Liu, Peter Abbink, David Ng’ang’a, Joseph P. Nkolola, Amanda L. Brinkman, Lauren Peter, Benjamin C. Lee, Jessica Jimenez, David Jetton, Jade Mondesir, Shanell Mojta, Abishek Chandrashekar, Katherine Molloy, Galit Alter, Jeffrey M. Gerold, Alison L. Hill, Mark G. Lewis, Maria G. Pau, Hanneke Schuitemaker, Joseph Hesselgesser, Romas Geleziunas, Jerome H. Kim, Merlin L. Robb, Nelson L. Michael & Dan H. Barouch The development of immunologic interventions that can target the viral reservoir in HIV-1-infected individuals is a major goal of HIV-1 research. However, little evidence exists that the viral reservoir can be sufficiently targeted to improve virologic control following discontinuation of antiretroviral therapy. Here we show that therapeutic vaccination with Ad26/MVA (recombinant adenovirus serotype 26 (Ad26) prime, modified vaccinia Ankara (MVA) boost) and stimulation of TLR7 (Toll-like receptor 7) improves virologic control and delays viral rebound following discontinuation of antiretroviral therapy in SIV-infected rhesus monkeys that began antiretroviral therapy during acute infection. Therapeutic vaccination with Ad26/MVA resulted in a marked increase in the magnitude and breadth of SIV-specific cellular immune responses in virologically suppressed, SIV-infected monkeys. TLR7 agonist administration led to innate immune stimulation and cellular immune activation. The combination of Ad26/MVA vaccination and TLR7 stimulation resulted in decreased levels of viral DNA in lymph nodes and peripheral blood, and improved virologic control and delayed viral rebound following discontinuation of antiretroviral therapy. The breadth of cellular immune responses correlated inversely with set point viral loads and correlated directly with time to viral rebound. These data demonstrate the potential of therapeutic vaccination combined with innate immune stimulation as a strategy aimed at a functional cure for HIV-1 infection.
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Springer Nature
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...