Publikationsdatum:
2014-10-03
Beschreibung:
Article Focal adhesion kinase (FAK) is frequently overexpressed in solid tumours. Here Batista et al. show that loss of FAK skews hematopoietic progenitors toward myeloid differentiation and promotes metastases, warning against the use of FAK inhibitors in anticancer therapies. Nature Communications doi: 10.1038/ncomms6054 Authors: Silvia Batista, Eleni Maniati, Louise E. Reynolds, Bernardo Tavora, Delphine M. Lees, Isabelle Fernandez, George Elia, Oriol Casanovas, Cristina Lo Celso, Thorsten Hagemann, Kairbaan Hodivala-Dilke
Digitale ISSN:
2041-1723
Thema:
Biologie
,
Chemie und Pharmazie
,
Allgemeine Naturwissenschaft
,
Physik
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