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  • Blackwell Publishing Ltd  (2)
  • Blackwell Publishing, Inc.  (2)
  • 2005-2009  (4)
  • 1975-1979
  • 1950-1954
  • 2005  (4)
  • 1
    Electronic Resource
    Electronic Resource
    Letter to the Editor (2005)
    350 Main Street , Malden , MA 02148 , USA , and 9600 Garsington Road , Oxford OX4 2DQ , UK . : Blackwell Publishing, Inc.
    Risk analysis 25 (2005), S. 0 
    Details
    ISSN: 1539-6924
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0272-4332.2005.00561.x
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  • 2
    Electronic Resource
    Electronic Resource
    APPLYING MACHINE LEARNING TO LOW-KNOWLEDGE CONTROL OF OPTIMIZATION ALGORITHMS (2005)
    Boston, USA and Oxford, UK : Blackwell Publishing, Inc.
    Computational intelligence 21 (2005), S. 0 
    Details
    ISSN: 1467-8640
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Computer Science
    Notes: This paper addresses the question of allocating computational resources among a set of algorithms to achieve the best performance on scheduling problems. Our primary motivation in addressing this problem is to reduce the expertise needed to apply optimization technology. Therefore, we investigate algorithm control techniques that make decisions based only on observations of the improvement in solution quality achieved by each algorithm. We call our approach “low knowledge” since it does not rely on complex prediction models, either of the problem domain or of algorithm behavior. We show that a low-knowledge approach results in a system that achieves significantly better performance than all of the pure algorithms without requiring additional human expertise. Furthermore the low-knowledge approach achieves performance equivalent to a perfect high-knowledge classification approach.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-8640.2005.00278.x
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  • 3
    Electronic Resource
    Electronic Resource
    Branched-chain fatty acid biosynthesis in a branched-chain amino acid aminotransferase mutant of Staphylococcus carnosus (2005)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 243 (2005), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Fatty acid biosynthesis by a mutant strain of Staphylococcus carnosus deficient in branched-chain amino acid aminotransferase (IlvE) activity was analysed. This mutant was unable to produce the appropriate branched-chain α-ketoacid precursors for branched-chain fatty acid biosynthesis from the amino acids valine, isoleucine, and leucine, and required the short branched chain acids 2-methylbutanoic acid or 2-methylpropanoic acid for growth in a defined medium. The isoleucine related metabolites, α-keto-β-methylvaleric acid and 2-methylbutanal also served as growth factors. Growth in rich medium and growth in defined medium supplemented with 2-methylpropanoic acid lead to extensive alteration of the fatty acid composition in the cell membrane. In rich medium, a change from 51.7% to 17.1%anteiso-C15:0, and from 3.6% to 33.9%iso-C14:0 fatty acids as compared to the wild-type strain was observed. Despite the deficiency in IlvE activity, the mutant strain was still able to produce the short chain carboxylic acids, 3-methylbutanoic acid and 2-methylpropanoic acid when cultivated in rich medium. Supplementation experiments employing deuterated glucose induced the valine biosynthetic pathway for 2-methylpropanoic acid production, revealing that the IlvE protein plays an important, but not essential role in the biosynthesis of branched-chain fatty acids and secondary metabolites in S. carnosus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/j.femsle.2004.11.041
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  • 4
    Electronic Resource
    Electronic Resource
    Characterization of outer membrane protein fractions of Bdellovibrionales (2005)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 243 (2005), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Bdellovibrio-and-like organisms (BALOs) are predatory bacteria that prey upon Gram-negative bacteria and are taxonomically subsumed in the order Bdellovibrionales. Despite their unique lifestyle, these bacteria show remarkable genotypic diversities. The outer membrane of the predators is likely to play an important role during the recognition and invasion stage, as well as in the intraperiplasmic growth phase. In this study, the outer membrane protein fractions of type strains of Bdellovibrio, Bacteriovorax and Peredibacter were investigated, revealing the presence of outer membrane proteins (Omps) similar to the major Omps of Bdellovibrio bacteriovorus. The primary structures of these Omps of Bdellovibrio sp. W, Bacteriovorax stolpii and Peredibacter starrii were elucidated by a combined mass spectrometric–reverse genetic approach. The similarity between the analyzed Omps of the investigated BALOs ranges from 32% to 89% showing conserved amino acid regions in their primary structure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/j.femsle.2004.12.006
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