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  • Wiley  (29)
  • Springer  (7)
  • American Association for the Advancement of Science (AAAS)  (5)
  • Geological Society of America (GSA)
  • 2015-2019  (31)
  • 2000-2004  (11)
  • 1995-1999
  • 1950-1954
  • 2017  (31)
  • 2003  (11)
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  • 2015-2019  (31)
  • 2000-2004  (11)
  • 1995-1999
  • 1950-1954
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  • 1
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    Stratospheric memory and skill of extended-range weather forecasts (2003)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2003-08-02
    Description: We use an empirical statistical model to demonstrate significant skill in making extended-range forecasts of the monthly-mean Arctic Oscillation (AO). Forecast skill derives from persistent circulation anomalies in the lowermost stratosphere and is greatest during boreal winter. A comparison to the Southern Hemisphere provides evidence that both the time scale and predictability of the AO depend on the presence of persistent circulation anomalies just above the tropopause. These circulation anomalies most likely affect the troposphere through changes to waves in the upper troposphere, which induce surface pressure changes that correspond to the AO.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baldwin, Mark P -- Stephenson, David B -- Thompson, David W J -- Dunkerton, Timothy J -- Charlton, Andrew J -- O'Neill, Alan -- New York, N.Y. -- Science. 2003 Aug 1;301(5633):636-40.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Northwest Research Associates, 14508 NE 20th Street, Bellevue, WA, 98007, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12893941" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Future Caribbean temperature and rainfall extremes from statistical downscaling (2017)
    Wiley
    Details
    Publication Date: 2017-08-12
    Description: ABSTRACT The Statistical Downscaling Model (SDSM) is used to investigate future projections of daily minimum and maximum temperature extremes for 45 stations and rainfall extremes for 39 stations across the Caribbean and neighbouring regions. Models show good skill in reproducing the monthly climatology of the mean daily temperatures and the frequencies of warm days, warm nights, cool days and cool nights between 1961 and 2001. Models for rainfall exhibit lower skill but generally capture the monthly climatology of mean daily rainfall and the spatial distribution of the mean annual maximum number of consecutive dry days (CDD) and mean annual count of days with daily rainfall above 10 mm (R10). Future projections suggest an increase (decrease) in warm (cool) days and nights by 2071–2099 under the A2 and B2 scenarios relative to 1961–1990. An increase in CDD is suggested for most stations except some eastern Caribbean stations and Bahamas. Decreases in RX1 (monthly maximum 1-day precipitation), R10 and R95p (annual total rainfall above the 95th percentile) are also suggested for some northern Caribbean locations and Belize under the A2 scenario, compared to a mixture of increases and decreases for the eastern Caribbean. Atmospheric predictors used in SDSM correlate well with known oceanic and atmospheric drivers of Caribbean climate, e.g. the Atlantic Multidecadal Oscillation (AMO) on a seasonal timescale. Atlantic sea surface temperatures and the Caribbean low level jet appear to have significant influence on Caribbean temperature and rainfall extremes. Initiatives have explored future Caribbean rainfall and temperature extremes. These relied on outputs from global and regional climate models and a weather generator. Here, the Statistical Downscaling Model (SDSM), a hybrid of regression and stochastic weather generator approaches is used. Results suggest more frequent warm events and variable responses in extreme rainfall by 2071–2099 under A2 and B2 scenarios. Atmospheric predictors in SDSM correlate well with known oceanic and atmospheric drivers of Caribbean climate, e.g. Atlantic Multidecadal Oscillation (AMO) on seasonal timescales.
    Print ISSN: 0899-8418
    Electronic ISSN: 1097-0088
    Topics: Geosciences , Physics
    Published by Wiley
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  • 3
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    What mediates tree mortality during drought in the southern Sierra Nevada? (2017)
    Wiley
    Details
    Publication Date: 2017-09-06
    Description: Severe drought has the potential to cause selective mortality within a forest, thereby inducing shifts in forest species composition. The southern Sierra Nevada foothills and mountains of California have experienced extensive forest dieback due to drought stress and insect outbreak. We used high-fidelity imaging spectroscopy (HiFIS) and light detection and ranging (LiDAR) from the Carnegie Airborne Observatory (CAO) to estimate the effect of forest dieback on species composition in response to drought stress in Sequoia National Park. Our aims were: (1) to quantify site-specific conditions that mediate tree mortality along an elevation gradient in the southern Sierra Nevada Mountains; (2) to assess where mortality events have a greater probability of occurring; and (3) to estimate which tree species have a greater likelihood of mortality along the elevation gradient. A series of statistical models were generated to classify species composition and identify tree mortality, and the influences of different environmental factors were spatially quantified and analyzed to assess where mortality events have a greater likelihood of occurring. A higher probability of mortality was observed in the lower portion of the elevation gradient, on southwest and west-facing slopes, in areas with shallow soils, on shallower slopes, and at greater distances from water. All of these factors are related to site water balance throughout the landscape. Our results also suggest that mortality is species-specific along the elevation gradient, mainly affecting Pinus ponderosa and Pinus lambertiana at lower elevations. Selective mortality within the forest may drive long-term shifts in community composition along the elevation gradient. This article is protected by copyright. All rights reserved.
    Print ISSN: 1051-0761
    Electronic ISSN: 1939-5582
    Topics: Biology
    Published by Wiley on behalf of The Ecological Society of America (ESA).
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  • 4
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    Wave Transformation Across a Macrotidal Shore Platform Under Low to Moderate Energy Conditions (2017)
    Wiley
    Details
    Publication Date: 2017-09-07
    Description: We investigate how waves are transformed across a shore platform as this is a central question in rock coast geomorphology. We present results from deployment of three pressure transducers over four days, across a sloping, wide (~200 m) cliff-backed shore platform in a macrotidal setting, in South Wales, United Kingdom. Cross shore variations in wave heights were evident under the predominantly low to moderate (significant wave height 〈 1.4 m) energy conditions measured. At the outer transducer 50 m from the seaward edge of the platform (163 m from the cliff) high tide water depths were 8+ m meaning that waves crossed the shore platform without breaking. At the mid platform position water depth was 5 m. Water depth at the inner transducer (6 m from the cliff platform junction) at high tide was 1.4 m. This shallow water depth forced wave breaking, thereby limiting wave heights on the inner platform. Maximum wave height at the middle and inner transducers were 2.41 and 2.39 m respectively and significant wave height 1.35 m and 1.34 m respectively. Inner platform high tide wave heights were generally larger where energy was up to 335% greater than near the seaward edge where waves were smaller. Infragravity energy was less than 13% of the total energy spectra with energy in the swell, wind and capillary frequencies accounting for 87% of the total energy. Wave transformation is thus spatially variable and is strongly modulated by platform elevation and the tidal range. While shore platforms in microtidal environments have been shown to be highly dissipative, in this macro-tidal setting up to 90% of the offshore wave energy reached the landward cliff at high tide, so that the shore platform cliff is much more reflective.
    Print ISSN: 0197-9337
    Electronic ISSN: 1096-9837
    Topics: Geography , Geosciences
    Published by Wiley
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  • 5
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    The story of a Yakima fold and how it informs late Neogene and Quaternary backarc deformation in the Cascadia subduction zone, Manastash anticline, Washington, USA (2017)
    Wiley
    In: Tectonics
    Details
    Publication Date: 2017-09-13
    Description: The Yakima folds of central Washington, USA are prominent anticlines that are the primary tectonic features of the backarc of the northern Cascadia subduction zone. What accounts for their topographic expression and how much strain do they accommodate and over what time period? We investigate Manastash anticline, a north-vergent fault propagation fold typical of structures in the fold province. From retrodeformation of line- and area-balanced cross sections, the crust has horizontally shortened by 11% (0.8-0.9 km). The fold, and by inference all other folds in the fold province, formed no earlier than 15.6 Ma as they developed on a landscape that was reset to negligible relief following voluminous outpouring of Grande Ronde Basalt. Deformation is accommodated on two fault sets including west-northwest-striking frontal thrust faults and shorter north- to northeast-striking faults. The frontal thrust fault system is active with late Quaternary scarps at the base of the range front. The fault-cored Manastash anticline terminates to the east at the Naneum anticline and fault; activity on the north-trending Naneum structures predates emplacement of the Grande Ronde Basalt. The west-trending Yakima folds and west-striking thrust faults, the shorter north to northeast striking faults, and the Naneum fault together constitute the tectonic structures that accommodate deformation in the low-strain-rate environment in the backarc of the Cascadia Subduction Zone.
    Print ISSN: 0278-7407
    Electronic ISSN: 1944-9194
    Topics: Geosciences
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 6
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    Molecular and cellular reorganization of neural circuits in the human lineage (2017)
    American Association for the Advancement of Science (AAAS)
    In: Science
    Details
    Publication Date: 2017-11-24
    Description: To better understand the molecular and cellular differences in brain organization between human and nonhuman primates, we performed transcriptome sequencing of 16 regions of adult human, chimpanzee, and macaque brains. Integration with human single-cell transcriptomic data revealed global, regional, and cell-type–specific species expression differences in genes representing distinct functional categories. We validated and further characterized the human specificity of genes enriched in distinct cell types through histological and functional analyses, including rare subpallial-derived interneurons expressing dopamine biosynthesis genes enriched in the human striatum and absent in the nonhuman African ape neocortex. Our integrated analysis of the generated data revealed diverse molecular and cellular features of the phylogenetic reorganization of the human brain across multiple levels, with relevance for brain function and disease.
    Keywords: Neuroscience
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Prior alcohol use enhances vulnerability to compulsive cocaine self-administration by promoting degradation of HDAC4 and HDAC5 (2017)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2017-11-02
    Description: Addiction to cocaine is commonly preceded by experiences with legal or decriminalized drugs, such as alcohol, nicotine, and marijuana. The biological mechanisms by which these gateway drugs contribute to cocaine addiction are only beginning to be understood. We report that in the rat, prior alcohol consumption results in enhanced addiction-like behavior to cocaine, including continued cocaine use despite aversive consequences. Conversely, prior cocaine use has no effect on alcohol preference. Long-term, but not short-term, alcohol consumption promotes proteasome-mediated degradation of the nuclear histone deacetylases HDAC4 and HDAC5 in the nucleus accumbens, a brain region critical for reward-based memory. Decreased nuclear HDAC activity results in global H3 acetylation, creating a permissive environment for cocaine-induced gene expression. We also find that selective degradation of HDAC4 and HDAC5, facilitated by the class II–specific HDAC inhibitor MC1568, enhances compulsive cocaine self-administration. These results parallel our previously reported findings that the gateway drug nicotine enhances the behavioral effects of cocaine via HDAC inhibition. Together, our findings suggest a shared mechanism of action for the gateway drugs alcohol and nicotine, and reveal a novel mechanism by which environmental factors may alter the epigenetic landscape of the reward system to increase vulnerability to cocaine addiction.
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Bragg coherent diffractive imaging of single-grain defect dynamics in polycrystalline films (2017)
    American Association for the Advancement of Science (AAAS)
    In: Science
    Details
    Publication Date: 2017-05-19
    Description: Polycrystalline material properties depend on the distribution and interactions of their crystalline grains. In particular, grain boundaries and defects are crucial in determining their response to external stimuli. A long-standing challenge is thus to observe individual grains, defects, and strain dynamics inside functional materials. Here we report a technique capable of revealing grain heterogeneity, including strain fields and individual dislocations, that can be used under operando conditions in reactive environments: grain Bragg coherent diffractive imaging (gBCDI). Using a polycrystalline gold thin film subjected to heating, we show how gBCDI resolves grain boundary and dislocation dynamics in individual grains in three-dimensional detail with 10-nanometer spatial and subangstrom displacement field resolution. These results pave the way for understanding polycrystalline material response under external stimuli and, ideally, engineering particular functions.
    Keywords: Materials Science
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 9
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    New Insights on the Relative Contributions of Coastal Processes and Tectonics to Shore Platform Development following the Kaikoura Earthquake (2017)
    Wiley
    Details
    Publication Date: 2017-05-19
    Description: ABSTRACT We describe the immediate impact of the 14 November 2016 Kaikoura magnitude 7.8 (Mw) earthquake on shore platforms and cliffs around Kaikoura Peninsula. The earthquake caused an instantaneous uplift of ~1.01 m of the peninsula. We resurveyed 7 profiles previously used for erosion monitoring and observed changes in the configuration of the shoreline. The coseismic uplift has fundamentally changed the process regime operating on the platforms and altered the future trajectory of shore platform and cliff development. Our observations highlight the interplay of waves, weathering, biology and tectonics. At this location tectonism strongly modulates the process regime, driving instantaneous changes in morphology and altering rates and patterns of erosion. Finally, the uplift of the Kaikoura coast has implications for changing resilience to climate change and sea level rise.
    Print ISSN: 0197-9337
    Electronic ISSN: 1096-9837
    Topics: Geography , Geosciences
    Published by Wiley
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  • 10
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    Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors (2017)
    American Association for the Advancement of Science (AAAS)
    In: Science
    Details
    Publication Date: 2017-04-21
    Description: Dendritic cells (DCs) and monocytes play a central role in pathogen sensing, phagocytosis, and antigen presentation and consist of multiple specialized subtypes. However, their identities and interrelationships are not fully understood. Using unbiased single-cell RNA sequencing (RNA-seq) of ~2400 cells, we identified six human DCs and four monocyte subtypes in human blood. Our study reveals a new DC subset that shares properties with plasmacytoid DCs (pDCs) but potently activates T cells, thus redefining pDCs; a new subdivision within the CD1C + subset of DCs; the relationship between blastic plasmacytoid DC neoplasia cells and healthy DCs; and circulating progenitor of conventional DCs (cDCs). Our revised taxonomy will enable more accurate functional and developmental analyses as well as immune monitoring in health and disease.
    Keywords: Immunology, Online Only
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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