ALBERT

Beschreibung: BACKGROUND: As a medical emergency that can affect even well-screened, healthy individuals, peritonitis developing during a long-duration space exploration mission may dictate deviation from traditional clinical practice due to the absence of otherwise indicated surgical capabilities. Medical management can treat many intra-abdominal processes, but treatment failures are inevitable. In these circumstances, percutaneous aspiration under sonographic guidance could provide a "rescue" strategy. Hypothesis: Sonographically guided percutaneous aspiration of intra-peritoneal fluid can be performed in microgravity. METHODS: Investigations were conducted in the microgravity environment of NASA's KC-135 research aircraft (0 G). The subjects were anesthetized female Yorkshire pigs weighing 50 kg. The procedures were rehearsed in a terrestrial animal lab (1 G). Colored saline (500 mL) was introduced through an intra-peritoneal catheter during flight. A high-definition ultrasound system (HDI-5000, ATL, Bothell, WA) was used to guide a 16-gauge needle into the peritoneal cavity to aspirate fluid. RESULTS: Intra-peritoneal fluid collections were easily identified, distinct from surrounding viscera, and on occasion became more obvious during weightless conditions. Subjectively, with adequate restraint of the subject and operators, the procedure was no more demanding than during the 1-G rehearsals. CONCLUSIONS: Sonographically guided percutaneous aspiration of intra-peritoneal fluid collections is feasible in weightlessness. Treatment of intra-abdominal inflammatory conditions in spaceflight might rely on pharmacological options, backed by sonographically guided percutaneous aspiration for the "rescue" of treatment failures. While this risk mitigation strategy cannot guarantee success, it may be the most practical option given severe resource limitations.

Beschreibung: The Inflatable Re-entry Vehicle Experiment 3 (IRVE-3) was conducted from the NASA Wallops Flight Facility on July 23, 2012. Launched on a Black Brant XI sounding rocket, the IRVE-3 research vehicle achieved an apogee of 469 km, deployed and inflated a Hypersonic Inflatable Aerodynamic Decelerator (HIAD), re-entered the Earth's atmosphere at Mach 10 and achieved a peak deceleration of 20 g's before descending to splashdown roughly 20 minutes after launch. This paper presents the filtering methodology and results associated with the development of the Best Estimated Trajectory of the IRVE-3 flight test. The reconstructed trajectory is compared against project requirements and pre-flight predictions of entry state, aerodynamics, HIAD flexibility, and attitude control system performance.

Beschreibung: No abstract available