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  • Springer  (21)
  • 1995-1999  (21)
  • 1980-1984
  • 1940-1944
  • 1999  (21)
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Keywords
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  • 1995-1999  (21)
  • 1980-1984
  • 1940-1944
Year
  • 1
    Electronic Resource
    Electronic Resource
    Reptational dynamics of a polymer chain is stable against kinematic disorder (1999)
    Springer
    The European physical journal 10 (1999), S. 105-117 
    Details
    ISSN: 1434-6036
    Keywords: PACS. 83.20.Fk Reptation theories - 83.20.Jp Computer simulation - 83.10.Nn Polymer dynamics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: We study the diffusive motion of a (non-selfinteracting) chain through a quenched random environment, constructed such that it influences only the local dynamics but not the equilibrium configuration of the chain. Our Monte Carlo results show that this type of disorder, which we call kinematic, does not ruin reptation. This is in sharp contrast to disorder including also entropic traps and it supports the view that reptation prevails in melts, where in contrast to a gel entropic trapping is absent. Our data show the characteristic features of reptation, irrespective of the dilution or randomness of the kinematic obstacles. Our Monte Carlo results are in quantitative agreement with our recent detailed analytical evaluation of the reptation model (J. Stat. Phys. 90, 1325 (1998)). The analysis suggests that we effectively see reptation of a “blob”-chain, where the size of the blob rapidly increases with decreasing obstacle concentration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100510050834
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  • 2
    Electronic Resource
    Electronic Resource
    Effects of captopril and enalapril on electroencephalogram and cognitive performance in healthy volunteers (1999)
    Springer
    European journal of clinical pharmacology 55 (1999), S. 255-257 
    Details
    ISSN: 1432-1041
    Keywords: Key words Angiotensin-converting enzyme inhibitors ; Central effects ; Healthy volunteers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: Captopril and enalapril have been reported to influence cognitive functions and quality of life in hypertensive patients. Methods: The effects of captopril (12.5 mg and 25 mg) and enalapril (5 mg and 10 mg) administered during 7-day periods on electroencephalogram (EEG), cognitive functions, and subjective assessments were investigated in healthy males. Results: Neither captopril nor enalapril influenced EEG and cognitive functions compared with placebo. Captopril 12.5 mg decreased subjective activity compared with placebo. Enalapril did not alter subjective ratings. Both systolic and diastolic blood pressure were significantly lower after administration of captopril 25 mg, whereas blood pressure was unaffected by enalapril compared with placebo. Conclusion: Our results suggest that central effects of captopril and enalapril were minor and not constant in young healthy men.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002280050625
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  • 3
    Electronic Resource
    Electronic Resource
    Optimization of the Thermal Radiation Extinction of Silicon Carbide in a Silica Powder Matrix (1999)
    Springer
    Journal of thermal analysis and calorimetry 56 (1999), S. 77-85 
    Details
    ISSN: 1572-8943
    Keywords: silicon carbide ; specific extinction ; thermal conductivity ; thermal radiation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract In order to optimize the infrared extinction of a SiC-powder in a silica powder matrix, Mie scattering calculations for spherical SiC-particles have been performed. A single oscillator-model was applied to calculate the optical constants of SiC. Taking into account the particle size distribution of a commercially available SiC-powder, its wavelength dependent extinction coefficient was calculated. The result is in very good agreement with the extinction spectrum of the powder derived by infrared optically measurements. Mie scattering theory also was used to find the optimum mean SiC-particle diameter of a mixture of 20% SiC-powder and 80% silica powder.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1010131324100
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  • 4
    Electronic Resource
    Electronic Resource
    Butyrylcholinesterase Is Complexed with Transferrin in Chicken Serum (1999)
    Springer
    The protein journal 18 (1999), S. 205-214 
    Details
    ISSN: 1573-4943
    Keywords: Cholinergic system ; iron transport protein ; chicken BChE partial sequence ; serum-cholinesterase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The function of the enzyme butyrylcholinesterase (BChE) both in serum and in brain is unclear. In serum, BChE has been found complexed with several biomedically relevant proteins, with which it could function in concert. Here, the existence of a similar complex formed between BChE and sero-transferrin from adult chicken serum was elucidated. In order to identify both proteins unequivocally, we improved methods to highly purify the 81-kDa BChE and the coisolated 75-kDa transferrin, which then allowed us to tryptically digest and sequence the resulting peptides. The sequences as revealed for BChE peptides were highly identical to mammalian BChEs. A tight complex formation between the two proteins could be established (a) since transferrin is coisolated along with BChE over three steps including procainamide affinity chromatography, while transferrin alone is not bound to this affinity column, and (b) since imunoprecipitation experiments of whole serum with a transferrin-specific antiserum allows us to detect BChE in the precipitate with the BChE-specific monoclonal antibody 7D11. The possible biomedical implications of a complex between transferrin and BChE which here has been shown to exist in chicken serum are briefly discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1020632207361
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  • 5
    Electronic Resource
    Electronic Resource
    Improving reliability of large software systems (1999)
    Springer
    Annals of software engineering 8 (1999), S. 3-51 
    Details
    ISSN: 1573-7489
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract Improving field performance of telecommunication systems is the key objective of both telecom suppliers and operators, as an increasing amount of business critical systems worldwide are relying on dependable telecommunication. Early defect detection improves field performance in terms of reduced field failure rates and reduced intrinsic downtime. This paper describes an integrated approach to improve early defect detection and thus field reliability of telecommunication switching systems. The assumptions at the start of the projects discussed in this paper are: Wide application of code inspections and thorough module testing must lead to a lower fault detection density in subsequent phases. At the same time criteria for selecting the most critical components for code reviews, code inspections and module test are provided in order to optimize efficiency. The primary goal is to identify critical components and to make failure predictions as early as possible during the life cycle and hence reduce managerial risk combined with too early or too late release of such a system to the field. During test release time prediction and field performance prediction are both based on tailored and superposed ENHPP reliability models. Experiences from projects of Alcatel’s Switching and Routing Division are included to show practical impacts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018971212809
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  • 6
    Electronic Resource
    Electronic Resource
    Complete Systems of Lines on a Hermitian Surface over a Finite Field (1999)
    Springer
    Designs, codes and cryptography 17 (1999), S. 253-268 
    Details
    ISSN: 1573-7586
    Keywords: Hermitian surface ; complete partial spread
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract The aim is to find the maximum size of a set of mutually ske lines on a nonsingular Hermitian surface in PG(3, q) for various values of q. For q = 9 such extremal sets are intricate combinatorial structures intimately connected ith hemisystems, subreguli, and commuting null polarities. It turns out they are also closely related to the classical quartic surface of Kummer. Some bounds and examples are also given in the general case.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026439528939
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  • 7
    Electronic Resource
    Electronic Resource
    Biorecognition of HPMA Copolymer-Adriamycin Conjugates by Lymphocytes Mediated by Synthetic Receptor Binding Epitopes (1999)
    Springer
    Pharmaceutical research 16 (1999), S. 1010-1019 
    Details
    ISSN: 1573-904X
    Keywords: T-cells ; B-cells ; HPMA copolymer ; drug carrier ; targeting ; cancer therapy ; CD21 receptor ; adriamycin ; doxorubicin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Purpose. The EDPGFFNVE nonapeptide (NP) was recognized as the CD21 (CR2) binding epitope of the Epstein-Barr virus (EBV) gp350/ 220 envelope glycoprotein which mediates the virus attachment to human B lymphocytes (Nemerow et al., Cell 56:369-377, 1989). Here we evaluated the targeting potential of a synthetic receptor binding epitope (NP) covalently attached to a water-soluble polymeric drug carrier. In particular, the biorecognition of N-(2-hydroxypropyl) metha-crylamide (HPMA) copolymer-NP conjugates by B- and T-cells and the cytotoxicity of HPMA copolymer-NP-adriamycin (ADR) conjugates toward B-cells, T-cells, and peripheral blood lymphocytes (PBL) were evaluated. Methods. HPMA copolymer-NP and optionally ADR conjugates varying in the NP density and mode of NP attachment were incubated with Raji B-cells (human Burkitt's lymphoma), CCRF-CEM T-cells (acute human lymphoblastic leukemia), and CCRF-HSB-2 T-cells (human lymphoblastic leukemia). The kinetics of binding was studied, the Langmuir adsorption isotherms analyzed, binding constants calculated, and IC50 doses determined. Results. Flow cytometry studies revealed that binding was homogeneous to both cell types. The apparent binding constants to T-cells were about two times higher when compared to B-cells. The binding and cytotoxicity increased with increased amount of epitopes per polymer chain. Attachment of the NP via a GFLG spacer resulted in increased biorecognition when compared with conjugates containing NP bound via a GG spacer. HPMA copolymer-NP-ADR conjugates possessed specific cytotoxicity to T- and B-malignant cells. Concentrations, which were lethal to the latter, were not toxic for PBL. Conclusions. The data obtained seem to indicate the potential of the HPMA copolymer-NP conjugates as polymer anticancer drug carriers targetable to immunocompetent cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018975414165
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  • 8
    Electronic Resource
    Electronic Resource
    Karyotype constancy and genome size variation in BulgarianCrepis foetida s. l. (Asteraceae) (1999)
    Springer
    Plant systematics and evolution 217 (1999), S. 245-257 
    Details
    ISSN: 1615-6110
    Keywords: Asteraceae ; Crepis foetida ; Subspecies ; idiograms ; haematoxylin staining ; Giemsa C-banding ; fluorochrome banding ; Ag-NOR staining ; genome size ; Feulgen densitometry ; propidium iodide flow cytometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Ten populations ofCrepis foetida from Bulgaria belonging to the three subspeciesfoetida, rhoeadifolia, andcommutata were analyzed karyologically using haematoxylin staining, Giemsa C-banding, fluorochrome banding, Ag-NOR staining, Feulgen cytophotometry (scanning densitometry and video-based image analysis), and propidium iodide flow cytometry. The quantitatively-evaluated karyotype structure was similar among all populations, with minor variation in a few intercalary sites only and in the amount of NOR-associated heterochromatin (satellites). In contrast to the karyotypic constancy the genome size ofC. foetida subsp.commutata was about 10% lower than those of the other two subspecies, which had similar genome sizes. The genome size measurements using three different methods resulted in highly correlated data. The genome size difference adds some weight to previous taxonomic opinions treatingC. foetida subsp.commutata at species level, asC. commutata.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00984369
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  • 9
    Electronic Resource
    Electronic Resource
    Relativistic properties of the quark-antiquark potential (1999)
    Springer
    The European physical journal 7 (1999), S. 539-542 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. The relativistic transformation properties of the heavy quark-antiquark interaction potential are considered in the framework of the relativistic quark model. A special attention is paid to the long-range (confining) contribution to the spin-independent part of $q\bar q$ interaction. The retardation effects are consistently taken into account.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100529801021
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  • 10
    Electronic Resource
    Electronic Resource
    String representation of field correlators in the Dual Abelian Higgs Model (1999)
    Springer
    The European physical journal 8 (1999), S. 343-351 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. By making use of the path integral duality transformation, we derive the string representation for the partition function of an extended Dual Abelian Higgs Model containing gauge fields of external currents of electrically charged particles. By the same method, we obtain the corresponding representations for the generating functionals of gauge field and monopole current correlators. In the case of bilocal correlators, the obtained results are found to be in agreement with the dual Meissner scenario of confinement and the Stochastic Model of the QCD vacuum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100529901075
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