ISSN:
1434-1948
Keywords:
p-Ethynylphenylalanine
;
Alkyne-bridged α-amino acids
;
N,O-Chelate complexes
;
Ferrocenes
;
Schiff bases
;
Platinum
;
Gold
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The palladium-mediated coupling of p-ethynylphenylalanine (p-epa) with different halogenated benzenes yielded alkyne-bridged α-amino acids. A series of cationic mono- to hexanuclear (Ph3P)2Pt complexes with the anions of p-ethynylphenylalanine and alkynyl- or benzene-bridged di-, tri-, tetra- and hexa-ethynyl phenylalanines as N,O-chelate ligands was prepared. N-t-Boc-p-ethynylphenylalanine methyl ester was metal-substituted to give complexes of the types Ph3PAu-C≡C-R and (Et3P)2Pt(C≡CR)2. The benzene-bridged di-, tri-, tetra- and hexa-p-ethynylphenylalanine methyl esters form Schiff bases with ferrocene aldehyde and a tripodal ligand was obtained from Ph2PCH2CH2CH2NH2 and the benzene-bridged tri-ethynylphenylalanine. The structure of (Ph3P)2Pt[NH2C(H)(CH2C6H4C≡CH)CO2]+ BF4- was determined by X-ray diffraction.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
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