ISSN:
1573-6830
Keywords:
ischemic brain injury
;
superoxide dismutase
;
SOD-1 transgenic mice
;
nitric oxide
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract 1. Nitric oxide radicals (NO) play an important role in the pathophysiology of focal cerebral ischemia. 2. Vascular NO can reduce ischemic brain injury by increasing CBF, whereas neuronal NO may mediate neurotoxicity following brain ischemia, mainly by its reaction with superoxide to generate peroxynitrite. 3. These findings could contribute to a strategy for the treatment of cerebral ischemia.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1020677701368
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