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  • Ascertainment bias  (1)
  • Bjerkandera adusta  (1)
  • Danaidae
  • 1995-1999  (2)
  • 1980-1984
  • 1930-1934
  • 1920-1924
  • 1998  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Reaction of manganese peroxidase ofBjerkandera adusta with synthetic lignin in acetone solution (1998)
    Springer
    Journal of wood science 44 (1998), S. 486-490 
    Details
    ISSN: 1611-4663
    Keywords: Lignin biodegradation ; Manganese peroxidase ; Bjerkandera adusta ; Acetone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The reaction of manganese peroxidase (MnP) of the white-rot fungusBjerkandera adusta with synthetic lignin dehydrogenation polymer, DHP) in acetone medium was investigated. Gel-permeation chromatography of the DHP treated by MnP demonstrated depolymerization of syringyl DHP in the reaction mixture containing 70% acetone; moreover, concomitant repolymerization occurred to give highly polymerized products. Guaiacyl DHP was only repolymerized by MnP in the same acetone solution without giving degradation products. Addition of ascorbic acid to reaction mixtures containing acetone resulted in preferential depolymerization of syringyl DHP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00833415
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  • 2
    Electronic Resource
    Electronic Resource
    Anticipation in Japanese families with schizophrenia (1998)
    Springer
    Journal of human genetics 43 (1998), S. 217-223 
    Details
    ISSN: 1435-232X
    Keywords: Key words Anticipation ; Schizophrenia ; Ascertainment bias ; Cohort effect ; Trinucleotide repeats expansion ; Affected two-generation pair method ; Genomic imprinting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The identification of anticipation in schizophrenia is a recent focus in the genetic epidemiology of schizophrenia, although it involves some controversial methodological issues. We explored the evidence of anticipation among 44 Japanese two-generation pairs with schizophrenia found by reviewing nine years of admission records (1986–1994) at the Department of Neuropsychiatry, Nagasaki University Hospital and Michino-o Hospital, Nagasaki. The 44 pairs consisted of 27 two-generation pairs of first-degree relatives group (FDRG) and 17 pairs of second-degree relatives group (SDRG). On pairwise comparison and a life table analysis, the age at onset (AO) was significantly earlier in the lower generation (G2) than in the upper generation (G1) in all of the pairs and in the two subgroups, FDRG and SDRG. Earlier AO was shown in G2 even after minimizing some statistical biases for the study of anticipation in schizophrenia. A significant earlier mean AO was found in G2 even when a cohort effect was controlled for. There was no marked difference in AO between paternal and maternal transmission. These results provide further evidence for epidemiological anticipation, suggesting biological anticipation such as the involvement of trinucleotide repeats expansion in G2. The limitations of the study are also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100380050076
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