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  • 1
    Electronic Resource
    Electronic Resource
    TEMPERATURES IN PROTOPLANETARY DISKS (1998)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Earth and Planetary Sciences 26 (1998), S. 53-80 
    Details
    ISSN: 0084-6597
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Geosciences , Physics
    Notes: Abstract Observations of suspected planet-forming disks provide estimates of protoplanetary disk masses, surface temperatures, and the rate at which mass is infalling onto the disks. Analyses of primitive meteorites and comets and their components constrain the solar nebula's temperature at the locations and times where those components were formed. Theoretical models of disks undergoing the accretion of mass from an infalling cloud envelope predict disk temperatures in good agreement with these constraints: a moderately warm (500-1500 K) inner disk, surrounded by a cool (50-150 K) outer disk. These models have important implications for the depletion of volatiles in the inner Solar System, for mechanisms of disk evolution, and for the orbital distances at which terrestrial and gas giant planets form.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.earth.26.1.53
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  • 2
    Electronic Resource
    Electronic Resource
    trans-7,7-Diphenyl-7-silabicyclo[3.3.0]octan-3-one p-Tosylhydrazone Tetrahydrofuran Solvate (1998)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 54 (1998), S. 1856-1858 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270198005198
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  • 3
    Electronic Resource
    Electronic Resource
    Planet formation Twin planetary systems in embryo (1998)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 395 (1998), S. 320-321 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Size does matter, especially when it comes to radio telescopes. With a maximum extent of 36 km, the Very Large Array (VLA) of 27 radio telescopes yields sharper images at millimetre wavelengths than any other instrument. Rodríguez et al., reporting on page 355 of this issue, have ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/26331
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  • 4
    Electronic Resource
    Electronic Resource
    Astrometric signatures of giant-planet formation (1998)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 393 (1998), S. 141-143 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The discovery of giant planets orbiting nearby solar-type stars raises anew the question of how they formed. Two very different mechanisms have been proposed. Gravitational instability, is the process by which planets form directly from the gas in the accrection disk around the young star. The ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/30177
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  • 5
    Electronic Resource
    Electronic Resource
    Decreased phosphorylation of a low molecular weight protein by cGMP-dependent protein kinase in variant HL-60 cells resistant to nitric oxide- and cGMP-induced differentiation (1998)
    Springer
    Molecular and cellular biochemistry 185 (1998), S. 111-121 
    Details
    ISSN: 1573-4919
    Keywords: HL-60 cells ; differentiation ; cGMP-dependent protein kinase ; nitric oxide ; cGMP
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract We previously described the isolation of a variant subline of HL-60 cells that does not differentiate in response to nitric oxide (NO)-generating agents or to cGMP analogs [7]. The variant cells have normal guanylate cyclase activity and normal NO-induced increases in the intracellular cGMP concentration. We now show that the variant cells have normal cGMP-dependent protein kinase (G-kinase) activity, both by an in vitro and in vivo assay, and using two-dimensional gel electrophoresis we have identified six G-kinase substrates in the parental cells. Of these six proteins, we found considerably less phosphorylation of one of the proteins in the variant cells than in parental cells, both in vitro and in intact cells, and by 35S-methionine/35S-cysteine incorporation we found much less of this protein in the variant cells than in parental cells. The protein is a shared substrate of cAMP-dependent protein kinase (A-kinase); since cAMP analogs still induce differentiation of the variant cells, it appears that the NO/cGMP/G-kinase and cAMP/A-kinase signal transduction pathways share some but not all of the same target proteins in inducing differentiation of HL-60 cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006834324419
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  • 6
    Electronic Resource
    Electronic Resource
    Formation of Extrasolar Giant Planets: Core Accretion or Disk Instability? (1998)
    Springer
    Earth, moon and planets 81 (1998), S. 19-26 
    Details
    ISSN: 1573-0794
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006370021545
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  • 7
    Electronic Resource
    Electronic Resource
    NASA and the Search for Extrasolar Planets (1998)
    Springer
    Earth, moon and planets 81 (1998), S. 35-38 
    Details
    ISSN: 1573-0794
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006380328814
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  • 8
    Electronic Resource
    Electronic Resource
    Measurement of the hardness distribution in sapphire/NiAl composites using continuous indentation (1998)
    Springer
    Journal of materials science 33 (1998), S. 4101-4104 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract A variety of fibre coatings have been modelled as a means to reduce the thermal residual stresses in sapphire/NiAl composites, including the use of molybdenum as a compliant layer. However, no experimental studies have been performed to quantify the effect of these coatings on the residual stresses. Measuring the effect of the coatings in real composites is a difficult task given the limitations of the most common residual stress measurement methods, such as X-ray and neutron diffraction. In this study, a continuous indentation system was used to measure a spatial hardness distribution both within the molybdenum fibre coatings and the NiAl matrix. Because it has been shown that residual stresses effect the apparent hardness of a material, the hardness distribution should be indicative of the local residual stress state in the sample. The measured hardness distributions showed distinct trends, including an increasing hardness in the molybdenum as the NiAl interface is approached, a substantial increase in NiAl hardness at the fibre/coating boundary, and a decrease in NiAl hardness that is proportional to the distance from the fibre/coating boundary. The potential utility of continuous indentation systems for mapping the residual stresses in composites is briefly discussed. © 1998 Kluwer Academic Publishers
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1004428513627
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  • 9
    Electronic Resource
    Electronic Resource
    Use of a Hepta-tyr glycopeptide antibiotic as chiral selector in capillary electrophoresis (1998)
    Weinheim : Wiley-Blackwell
    Electrophoresis 19 (1998), S. 1742-1751 
    Details
    ISSN: 0173-0835
    Keywords: Antibiotics ; Chiral separations ; Enantiomers ; Drugs ; Herbicides ; Capillary electrophoresis ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: A new glycopeptide antibiotic, MDL 63,246 (Hepta-tyr), of the teicoplanin family, has been evaluated in capillary electrophoresis for the resolution of chiral compounds of pharmaceutical and environmental interest. Electrophoretic separations were carried out in a polyacrylamide-coated capillary using the partial filling-counter current mode with aqueous-organic buffers in the pH range 4-6. Experimental parameters affecting resolution, such as antibiotic concentration, buffer pH, organic modifier type and capillary temperature, were studied. The Hepta-tyr antibiotic exhibited a high enantiorecognition capability towards the studied compounds at very low concentrations (1-2 mg/mL). The optimum experimental conditions were achieved by using a buffer at pH 5 containing acetonitrile at 25°C.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/elps.1150191036
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  • 10
    Electronic Resource
    Electronic Resource
    Peptide capillary zone electrophoresis mass spectrometry of recombinant human erythropoietin: An evaluation of the analytical method (1998)
    Weinheim : Wiley-Blackwell
    Electrophoresis 19 (1998), S. 2654-2664 
    Details
    ISSN: 0173-0835
    Keywords: Glycoprotein ; Glycopeptide ; Peptide ; Capillary electrophoresis ; Mass spectrometry ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: An evaluation of capillary zone electrophoresis-mass spectrometry (CZE-MS) as an analytical methodology for the separation and characterization of complex glycopeptides and nonglycopeptide structures has been performed. The evaluation employed endoproteinase V8 digested recombinant human erythropoietin (rHuEPO) that was further fractionated by reverse phase chromatography. The peptides were subjected to sequence analysis and evaluated by capillary electrophoresis, with or without mass detection, for peptide purity. The peptide mass determined from the sequence was then compared to the mass obtained from CZE-MS. Glycosylation sites and carbohydrate branch patterns were easily determined, site specific microheterogeneity (either O-acetylation of N-acetylneur-aminic acids or lactosamine extensions of the carbohydrate chain length) was assessed directly, glycosylation site occupancy was evaluated qualitatively, and nonglycopeptides were resolved and analyzed on-line with ease. Incomplete peptide digestion products were detected and identified by CZE-MS. Protein sequence coverage by CZE-MS was 98.2 percent complete from a single map. Offline evaluation of peptide purity by CZE greatly aided the interpretation of multiple sequence analysis and, in validating that, the CZE-MS was detecting all peptides present. All off-line CZE and on-line CZE-MS experiments employed a capillary that was dynamically coated with Polybrene in the presence of polyethylene glycol; separations were conducted in 0.67 M formic acid.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/elps.1150191515
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