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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Circuits, systems and signal processing 17 (1998), S. 195-218 
    ISSN: 1531-5878
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Abstract In this two-part study we present a new design methodology for neural classifiers. The design procedure utilizes a multiclass vector quantization (MVQ) algorithm for information extraction from the training set. The extracted information suffices to specify the hidden layer in a canonical neural network architecture. The extracted information also leads to the specification of neuron inhibition rules and subsequently the design of the hidden layer-to-output map. In Part I of the study we focus attention on the MVQ algorithm and how it is used to extract information from a training set. The extracted information is referred to as thecodebook. The codebook is used to directly specify the hidden layer. This specification can take the form of a perceptron layer, a radial basis layer, or a heterogeneous layer involving a mixture of neuron types. These and otherh-layer specifications are determined directly from the same extracted information. The MVQ codebook also suffices to scale the activation function of each neuron. In Part II we consider the nonsimplistic hidden layer-to-output map design. We note that the MVQ algorithm, as it extracts information, decomposes the design set into disjoint neighborhoods. For each neighborhood we identify subsets of the hidden layer neurons, which are significant sensors for the neighborhood. For each such subset we construct an output map. Inhibition rules are established to ensure that the proper output map is activated. In benchmark simulations the overall design exhibits excellent performance, to the extent that we are hard pressed to identify bounds on performance, if any.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Circuits, systems and signal processing 17 (1998), S. 613-635 
    ISSN: 1531-5878
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Abstract In this two part study, we presented a new design methodology for neural classifiers. The design procedure utilizes a multiclass vector quantization, MVQ, algorithm for information extraction from the training set. The extracted information suffices to specify the hidden layer in a canonical neural network architecture. The extracted information also leads to the specification of neuron inhibition rules and subsequently to the design of the hidden layer to output map. In part I of that study, we focused attention on the MVQ algorithm and how it is used to extract information from a training set. The extracted information is used to directly specify the hidden layer. In part II, we consider the non-simplistic hidden layer to output map design. We note that the MVQ algorithm, as it extracts information, decomposes the design set into disjoint neighborhoods. For each neighborhood we identify subsets of the hidden layer neurons which are significant sensors for the neighborhood. For each subset we construct an output map. Inhibition rules are established to assure that the proper output map is activated. In benchmark simulations, the overall design exhibits performance, to the extent that we are hard pressed to identify bounds on performance, if any.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of industrial microbiology and biotechnology 21 (1998), S. 203-207 
    ISSN: 1476-5535
    Keywords: Keywords: fermentation; vegetable oils; tetracycline; Streptomyces aureofaciens
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: To evaluate their potential to enhance fermentation performance, vegetable oils were investigated in a model tetracycline fermentation. With sucrose as the carbon source, the fermentation efficiency of Streptomyces aureofaciens (ATCC 10762) was enhanced by the inclusion in the medium of low levels of vegetable oil. Soybean and sunflower oils significantly improved the rate of sucrose consumption and tetracycline production suggesting that oil is an excellent adjuvant for improving fermentation productivity. For optimum benefit, the dosage level was critical. Little difference was observed between crude and refined oils. These data contribute to the assessment of industrially available fermentation feedstocks, and to the development of new feedstock products for specific fermentation applications.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Applied categorical structures 6 (1998), S. 455-471 
    ISSN: 1572-9095
    Keywords: free 2-crossed modules ; free simplicial algebras
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract In this paper we give a construction of free 2-crossed modules. By the use of a ‘step-by-step’ method based on the work of André, we will give a description of crossed algebraic models for the steps in the construction of a free simplicial resolution of an algebra. This involves the introduction of the notion of a free 2-crossed module of algebras.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1432
    Keywords: Key words: Scanning force microscopy — Glycine oligomerization — Prebiotic peptide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract. Condensation reactions of the amino acid glycine on the surface of Cu(II)-exchanged hectorite are investigated using the technique of scanning force microscopy. Prebiotic conditions are simulated using alternate wetting and heating cycles. Concentration, immobilization, and subsequent polymerization resulting in glycine oligomers are seen to occur primarily at step edges or faults in the topmost layer. Condensation reactions also occur within tiny micropores or defects in the topmost layer. These reactions are facilitated by the availability of intergallery metal cations at the step edges or pores in the surface region.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of reducing space mission cost 1 (1998), S. 9-25 
    ISSN: 1572-9621
    Keywords: barter system ; Cassini ; cost containment ; instrument development ; project management ; resource allocation ; science management ; space payloads.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Using economic incentives to control costs is a new concept for space missions. The basic tenets of market-based approaches run counter to typical centralized management techniques often utilized for complex space missions. NASA's Cassini mission to Saturn used a market trading system to assist the Science Instrument Manager in guiding the development of the spacecraft's science payload. This system allowed science instrument teams to trade resources among themselves to best manage their resources (mass, power, data rate, and budget). Thus, Cassini Project management was no longer responsible for adjudicating and reallocating resources that result from instrument development problems. Instrument teams were responsible for directly managing their resources and if they ran into a development problem it was their responsibility to resolve their problem by descoping or through the use of a 'resource exchange.' Under the trading system, instrument cost growth was less than 1% and the total payload mass was under its allocation by 7%. This result is in stark contrast to the 50%–100% increases in these resources on past missions.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of reducing space mission cost 1 (1998), S. 119-132 
    ISSN: 1572-9621
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Market-based systems are those systems in which currency is used to express demand for a limited resource. In these systems, users `own' currency and exchange it for a desired commodity. Though used for thousands of years, market-based applications to space missions are still in their infancy. The first successful application was in 1992 with the Cassini Mission to Saturn. In this case, the sum total of mass and dollars for the science instruments had to fit within the allocated resource envelope. Results from the use of a market-based system show that the entire science payload grew from original estimates by only +1% for cost, and by −7% for mass. The next application was for Space Shuttle Secondary Payloads. In this application, available shuttle lift mass, number of lockers for secondary payloads, and available astronaut time had to be allocated between 5 NASA Users. Experiments showed that a market-based system can reduce the size of the required workforce needed to produce a manifest of the same quality as one produced `by committee.' Finally, a market-based system was experimentally applied to LightSAR science planning, a proposed joint NASA/Commercial RADAR mission. In this application, users were able to produce a conflict-free timeline of events remotely, of high science value, in about half the time required by more traditional methods.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1939
    Keywords: Key words Aphidae ; Parasitoids ; Species diversity ; Aphidiinae ; Assemblage size
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We used aphids (Aphidae) as a representative hemimetabolous host family to investigate patterns of parasitoid (Aphidiine) assemblage size. The aphidiine assemblages from 477 aphid species were used to estimate average assemblage size and the influence of eight ecological and taxonomic variables. Aphids species support an average of 1.7 aphidiine species. Aphid subfamily and invasion status (native or exotic) were the most important determinants of parasitoid richness, explaining 28% of the deviance in aphidiine assemblage size. Aphids within the largest aphid subfamily, the Aphidinae, support larger parasitoid assemblages than those in other subfamilies. Parasitoid diversity was also highest on exotic aphid hosts (within the Aphidinae) and on hosts in developed habitats (agricultural or urban), though the latter effect is weak. Patterns related to aphid food plant architecture were influenced by an interaction with aphid invasion status; parasitoid diversity drops with increasing architectural complexity on exotic aphids, whereas the diversities on native aphid hosts are similar on different plant types. Weak effects were also found for aphid food plant alternation (whether or not aphids switch hosts seasonally) and climate (annual range in temperature); alternating aphids support more parasitoids than non-alternating hosts, and parasitoid assemblage size is lowest in warm climates. Taxonomic isolation of aphids at the generic level showed no significant relationship with parasitoid diversity. Finally, in contrast to parasitoid assemblages on holometabolous hosts, sample size effects were weak for aphids, possibly due to the narrow host ranges of aphidiines.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-0878
    Keywords: Key words Extraocular muscle ; Cation ; Muscular dystrophy ; Merosin ; dy Mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Extraocular muscle is uniquely spared from damage in merosin-deficient congenital muscular dystrophy. Using a murine model, we have tested the hypothesis that the maintenance of calcium homeostasis is mechanistic in extraocular muscle protection. Atomic absorption spectroscopy has demonstrated a strong correlation between the perturbation of calcium homeostasis in hindlimb muscle that is severely damaged and the absence of changes in calcium in extraocular muscle. If, as in other skeletal muscles, extraocular muscle fibers are destabilized by merosin deficiency, we would expect an increase in total muscle calcium coupled with an adaptive response in the high capacity/speed of the sarcoplasmic reticulum of the eye muscle. However, we have not observed the expected increases in total muscle calcium content, Ca2+-ATPase activity, Na+/Ca2+ exchanger content, or smooth ER Ca2+-ATPase content that are predicted by this model. Instead, these results indicate that the increased membrane permeability that characterizes, and is potentially mechanistic in, myofiber degeneration in muscular dystrophy does not occur in merosin-deficient extraocular muscle. Thus, the high-capacity calcium-scavenging systems are not primarily responsible for extraocular muscle protection in muscular dystrophy.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Genetica 104 (1998), S. 259-263 
    ISSN: 1573-6857
    Keywords: chemical communication ; kin recognition ; mother‐infant interactions ; odor signatures ; olfaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Humans, like other mammals, are capable of discriminating between kin and non‐kin by olfactory cues alone. Shortly after birth, breastfed infants become familiar with, and respond preferentially to, their mother' unique odor signature. Mothers likewise recognize the characteristic scent of their newborn infant. Close biological relatives share somewhat similar odor signatures (presumably resulting from genetically mediated similarities in bodily biochemistry and metabolism) that could facilitate kin recognition.
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