ISSN:
0941-1216
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Synthesis of Cyanosubstituted Di- and Tetrahydropyridines in DIMCARB (Dimethylamine-CO2-Adduct)A new selective method for base-catalyzed ring closure reaction of acetophenones (1a-I) with malononitrile in DIMCARB (dimethylamine-CO2-addition-compound) as solvent of high dimethylamine concentration is reported, which allows effective syntheses of (1.2-dihydro-4-pyrid-6-yl)dicyanomethanides and 5-cyano-6-dicyanomehylene-1,2,3,6-tetrahydropyridines in good yields. The structure of the two new classes of compounds is proved by X-ray diffraction analysis.
Additional Material:
3 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19973390173
Permalink