Electronic Resource
Copenhagen
:
International Union of Crystallography (IUCr)
Acta crystallographica
52 (1996), S. 160-164
ISSN:
1399-0047
Source:
Crystallography Journals Online : IUCR Backfile Archive 1948-2001
Topics:
Chemistry and Pharmacology
,
Geosciences
,
Physics
Notes:
The structure of a tetragonal crystal of bovine pancreatic RNase B complexed with d(pA)4 was determined by molecular replacement and difference Fourier methods. This crystal belongs to space group P41212 and has unit-cell dimensions a = b = 44.5, c = 156.5 Å. The model consists of the enzyme and a tetranucleotide with fractional occupancies, suggesting multiple modes of oligonucleotide binding. It does not include any polysaccharide residues or solvent molecules. After refinement at 2.7 Å, the R value was 0.163 with acceptable stereochemistry. The model illustrates a set of well defined interactions for substrate binding, particularly between the central dinucleotide and the enzyme.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1107/S0907444995009127
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