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  • Articles  (28)
  • Springer  (28)
  • Molecular Diversity Preservation International
  • 2015-2019
  • 2000-2004
  • 1995-1999  (28)
  • 1995  (28)
Collection
Source
Keywords
Publisher
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  • 2015-2019
  • 2000-2004
  • 1995-1999  (28)
Year
Journal
Topic
  • 1
    Electronic Resource
    Electronic Resource
    Electrochemical mass transfer to regular packings in a bubble column (1995)
    Springer
    Journal of applied electrochemistry 25 (1995), S. 273-278 
    Details
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Notes: Abstract The behaviour of regular packings constructed from corrugated metal sheets was investigated since they constitute an attractive packing material for the electrochemical absorption of gases. Mass transfer coefficients for the regular packing contained in a circular electrolytical cell were determined by the electrochemical method with simulation of the absorption process by bubbling nitrogen through the column. Correlations for the mass transfer rate as a function of fluid dynamic parameters and fluid properties are presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00262967
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  • 2
    Electronic Resource
    Electronic Resource
    No evidence for medium effects in the12C(e, e'p)11Bg.s. reaction (1995)
    Springer
    The European physical journal 351 (1995), S. 353-354 
    Details
    ISSN: 1434-601X
    Keywords: 21.10.Pc ; 25.30.Dh ; 24.50.+g ; 27.20.+n
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The12C(e, e'p)11B g.s reaction has been measured in parallel and anti-parallel kinematics over ap m range of −120〈p m〈120 MeV/c at a centralT p of 90 MeV. In contrast to previous measurements at NIKHEF, both kinematics can be described without enhancement of the transverse form factor of the bound proton (η=0.98(5)). The spectroscopic factor for this transition as determined with the new Mainz data (S α =1.54(5)) is 22% smaller than the NIKHEF value.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01291135
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  • 3
    Electronic Resource
    Electronic Resource
    Breccias of the Adnet Formation: indicators of a Mid-Liassic tectonic event in the Northern Calcareous Alps (Salzburg/Austria) (1995)
    Springer
    International journal of earth sciences 84 (1995), S. 272-286 
    Details
    ISSN: 1437-3262
    Keywords: Synsedimentary tectonics ; Stratigraphy ; Depositional model ; Debris flows ; Submarine erosion ; Scheck breccia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Stratigraphy, lithology and depositional structures of Liassic red limestone-breccias of the Adnet Formation, including the ‘Adnet Scheck’, were studied at several outcrops of the Northern Calcareous Alps (NCA) south-east of Salzburg. A four-fold lithostratigraphic division is proposed for the Adnet Formation of the Osterhorn Mountains: the hemipelagic Schmiedwirt (Sinemurian) and Kehlbach (Carixian) members are separated from the pelagic Saubach Member (Toarcian) by a layer of amalgamated breccias (Scheck Member, probably Domerian to early Toarcian). Several other breccia beds occur locally from the base of the Kehlbach Member up to the lower Saubach Member. Although the sediments overlying the Scheck Member breccias are of coeval age, the ages of the underlying strata are very different. This can be explained by submarine Liassic erosion during a period of resedimentation from the middle Carixian until the early Toarcian. At least 10–15 m of partly lithified sediments were eroded by gravity flows. The entire Kehlbach Member and up to two-thirds of the Schmiedwirt Member were removed at Adnet. The breccias originated from submarine debris flows. Repeated flows over a long period and the depositional setting exclude a triggering by sea-level fluctuations. Most probably they arose from tectonically triggered slumps and slides of superficial sediments. The ‘Scheck’ was initiated on the steep upper slope of the drowned Triassic Adnet reef and flowed to the north-east. The Pliensbachian to early Toarcian period of tectonic activity indicated by the breccias was the most important during the Liassic in the Osterhorn Mountains and other parts of the NCA. From the large-scale regional distribution of the breccias and in accord with published data, a roughly northeast trending strike-slip fault zone is proposed, crossing the NCA south of the Osterhorn block, with a peaking activity during the Pliensbachian to early Toarcian as the cause of the tectonic movements.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00260440
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  • 4
    Electronic Resource
    Electronic Resource
    Head critical period and juvenile hormone titre during the last larval instar of the cockroach,Periplaneta americana (1995)
    Springer
    Cellular and molecular life sciences 51 (1995), S. 1094-1096 
    Details
    ISSN: 1420-9071
    Keywords: Head critical period ; juvenile hormone ; moult regulation ; Periplaneta americana
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract From neck ligation experiments with last instar larvae of the cockroachPeriplaneta americana it was concluded that the head critical period is reached around day 17, which corresponds to 59% of the last larval stage. At the same stage the juvenile hormone III titre in the hemolymph dropped to undectable levels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01946924
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  • 5
    Electronic Resource
    Electronic Resource
    Developmental regulation of presence of binding sites for neoglycoproteins and endogenous lectins in various embryonic stages of human lung, liver and heart (1995)
    Springer
    Development genes and evolution 204 (1995), S. 344-349 
    Details
    ISSN: 1432-041X
    Keywords: Development ; Lectin ; Neoglycoprotein Glycoconjugate ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Protein-carbohydrate interactions are supposed to play key roles in the mechanisms of cell adhesion, biosignalling and intracellular routing, warranting the analysis of the developmental course of expression of epitopes of this system. Thus, a panel of carrier-immobilized carbohydrate ligands was used as probes, namely lactose,N-acetylgalactosamine,N-acetylglucosamine, mannose, fucose and maltose. Additionally, an antibody to an endogenous β-galactoside-binding lectin (anti-galectin-1), the biotinylated lectin and two further human lectins, namely the macrophage migration inhibitory factor-binding sarcolectin and serum amyloid P component (SAP) that displays selectivity for sulphated sugars and mannose-6-phosphate, were included. They enabled us to assess the extent of the presence of respective binding sites in fixed sections from human lungs (pulmonary epithelial cells), livers (hepatocytes) and hearts (myocard cells) of 10–50 weeks gestation. Invariably, specific binding was detected in the three organ types, at least in certain stages. In most of the cases, the intensity of staining exhibited developmental regulation. The apparent patterns reveal similarities between the different cell types, as seen with immobilizedN-acetylglucosamine as well as with labelled galectin-1 and sarcolectin. However, drastic differences among such patterns with nearly opposite developmental courses do also occur, as detected for carrier-attached mannose and maltose residues. These results point to a potential importance for the detected glycohistochemical features in human development and substantiate the possibility of differential regulation of the presence of binding sites for distinct sugars within a certain organ and between the individual cell types of the monitored organs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02179503
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  • 6
    Electronic Resource
    Electronic Resource
    An intragenic deletion in the human PTPN6 gene affects transcriptional activity (1995)
    Springer
    Human genetics 〈Berlin〉 95 (1995), S. 713-715 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract An intragenic deletion in the human PTPN6 gene is described. The PTPN6 gene maps to chromosome 12p12-13 and is shown to possess two alternative first exons. A 1.7-kb deletion occurring in the intron between the two alternatively used first exons is the result of an illegitimate recombination between two Alu-type repeats. The deletion increases the transcriptional activity of the distal promotor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00209495
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  • 7
    Electronic Resource
    Electronic Resource
    Genetic duplication in Fusarium oxysporum (1995)
    Springer
    Current genetics 28 (1995), S. 173-176 
    Details
    ISSN: 1432-0983
    Keywords: Chromosome ; Electrophoretic karyotype ; Filamentous fungus ; Plant pathogen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Genomic clones hybridizing to anonymous, single-copy sequences were used to probe chromosomesized DNAs of Fusarium oxysporum f. sp. cubense separated by pulsed-field gel electrophoresis. As expected, most clones hybridized to single chromosome bands. However, two of eight “single-copy” clones hybridized to two chromosomes in some, but not all, of 14 isolates examined. This observation suggests a degree of genetic duplication in the fungus and is consistent with recent electrophoretic karyotype analysis indicating that intraspecific differences in genome size and chromosome number may be explained, at least in part, by persistent genetic duplication.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00315784
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  • 8
    Electronic Resource
    Electronic Resource
    Identifying chromosomal fragile sites from individuals: a multinomial statistical model (1995)
    Springer
    Human genetics 〈Berlin〉 95 (1995), S. 249-256 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The inability to identify fragile sites from data for single individuals remains the major obstacle to determining whether these chromosomal loci are predisposed to cancer-causing and evolutionary rearrangements. We describe a novel statistical model that is amenable to data from single individuals and that establishes site-specific chromosomal breakage as nonrandom with respect to the distribution of total breakage. Our method tests incrementally smaller subsets of the data for homogeneity under a multinomial model that assigns equal probabilites to a maximal set of nonfragile sites and unrestricted probabilities to the remaining fragile sites with significantly higher numbers of breaks. We show how standardized Pearson's chi-square (X 2) and likelihood-ratio (G 2) statistics can be appropriately used to measure goodness-of-fit for sparse contingency (individual-based) data in this model. A sample application of this approach indicates extensive variation in fragile sites among individuals and marked differences in fragile-site inferences from pooled as opposed to per-individual data.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00225189
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  • 9
    Electronic Resource
    Electronic Resource
    Direct molecular analysis of the fragile X syndrome in a sample of Egyptian and German patients using non-radioactive PCR and Southern blot followed by chemiluminescent detection (1995)
    Springer
    Human genetics 〈Berlin〉 96 (1995), S. 577-584 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Molecular genetic analysis of individuals from 6 Egyptian and 33 German families with fragile X syndrome and 240 further patients with mental retardation was performed applying a completely non-radioactive system. The aim of our study was the development of a non-radioactive detection method and its implementation in molecular diagnosis of the fragile X syndrome. Furthermore, we wanted to assess differences in the mutation sizes between Egyptian and German patients and between Egyptian and German carriers of a premutation. Using non-radioactive polymerase chain reaction (PCR), agarose gel electrophoresis and blotting of the PCR products, followed by hybridisation with a digoxigenin-labelled oligonucleotide probe (CGG)5 and chemiluminescent detection, we identified the fragile X full mutation (amplification of a CGG repeat in the FMR-1 gene ranging from several hundred to several thousand repeat units) in all patients. We observed no differences in the length of the CGG repeat between the Egyptian and German patients and carriers, respectively. However, in one prenatal diagnosis, we detected only one normal sized allele in a female fetus using the PCR-agarose assay, whereas Southern blot analysis with the digoxigenin labelled probe StB 12.3 revealed presence of a full mutation. Our newly established nonradioactive genomic blotting method is based on the conventional radioactive Southern blot analysis. Labelling of the probe StB 12.3 with digoxigenin via PCR allowed the detection of normal, premutated and fully mutated alleles. For exact sizing of small premutated or large normal alleles, we separated digoxigenin labelled PCR products through denaturing poly-acrylamide gelelectrophoresis (PAGE) and transfered them to a nylon membrane using a gel dryer. The blotted PCR-fragments can easily be detected with alkaline phosphate-labelled anti-digoxigenin antibody. The number of trinucleotide repeat units can be determined by scoring the detected bands against a digoxigenated M13 sequencing ladder. Our newly developed digoxigenin/chemiluminescence approach using PCR and Southern blot analysis provides reliable results for routine detection of full fragile X mutations and premutations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00197414
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  • 10
    Electronic Resource
    Electronic Resource
    An analysis of the zero differential overlap approximation. Towards an improved semiempirical MO method beyond it (1995)
    Springer
    Theoretical chemistry accounts 92 (1995), S. 13-47 
    Details
    ISSN: 1432-2234
    Keywords: Zero differential overlap ; Semiempirical MO methods ; Löwdin transformation ; Overlap density ; Mulliken approximation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary Some systematic errors of the zero differential overlap (ZDO) approximation in semiempirical molecular orbital (MO) methods are discussed. In π electron methods, a power series expansion of the inverse square rootS −1/2 of the overlap matrix and application of the Mulliken approximation to the two-electron integrals show that the ZDO Hamiltonian coincides with the Hamiltonian obtained by explicit performance of the Löwdin transformation up to first-order terms of diatomic overlap densities. Higher than first-order terms lead to a systematic up-shift of the canonical MO energies. Although a power series expansion ofS −1/2 is no longer possible in all-valence-electron methods, the MO levels resulting from the ZDO approximation are also systematically placed at too low energies, especially the low-lying occupied and the virtual MOs. A method based on explicit performance of the Löwdin transformation and retaining the simplicity of the ZDO approach for the calculation of Fock matrix elements is developed. The parameters of this method are obtained by very simple manipulations of the original ZDO parameters. Numerical calculations show that a considerable improvement of the MO energy spectrum in the inner valence region can be obtained in this way
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01134202
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