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  • Blackwell Publishing Ltd  (3)
  • 2020-2023
  • 2020-2021
  • 2000-2004  (1)
  • 1995-1999  (2)
  • 1965-1969
  • 1960-1964
  • 1925-1929
  • 2000  (1)
  • 1995  (2)
  • 1
    Electronic Resource
    Electronic Resource
    The MD Shell and its use to develop Dust-Expert (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Expert systems 12 (1995), S. 0 
    Details
    ISSN: 1468-0394
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Computer Science
    Notes: Abstract: In this paper we describe TheMD (The Methods Designer) shell and its use in the development of an expert system, known as Dust-Expert, for the relief of dust explosions. We begin by providing the motivation for the development of TheMD Shell by evaluating a prototype implementation of Dust-Expert using a conventional shell. This evaluation is carried out in terms of the transparency, reliability and extensibility of the system.The lessons learned from this evaluation have led to the development of TheMD Shell. We describe the main features of the shell which include more appropriate schemas, more complete explanation capabilities, a ranking scheme and equation-solving capabilities. We illustrate the use of the schemas and the importance of the equation-solving capabilities by examples from the domain of dust explosions. We also provide a formal specification of the ranking scheme that we adopt. We conclude by highlighting the benefits of our approach in comparison to the usual process of developing knowledge-based systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1468-0394.1995.tb00112.x
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  • 2
    Electronic Resource
    Electronic Resource
    Class IIa bacteriocins: biosynthesis, structure and activity (2000)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology reviews 24 (2000), S. 0 
    Details
    ISSN: 1574-6976
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: In the last decade, a variety of ribosomally synthesized antimicrobial peptides or bacteriocins produced by lactic acid bacteria have been identified and characterized. As a result of these studies, insight has been gained into fundamental aspects of biology and biochemistry such as producer self protection, membrane–protein interactions, and protein modification and secretion. Moreover, it has become evident that these peptides may be developed into useful antimicrobial additives. Class IIa bacteriocins can be considered as the major subgroup of bacteriocins from lactic acid bacteria, not only because of their large number, but also because of their activities and potential applications. They have first attracted particular attention as listericidal compounds and are now believed to be the next in line if more bacteriocins are to be approved in the future. The present review attempts to provide an insight into general knowledge available for class IIa bacteriocins and discusses common features and recent findings concerning these substances.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6976.2000.tb00534.x
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  • 3
    Electronic Resource
    Electronic Resource
    Detection and differentiation of the gene for toxin co-regulated pili (tcpA) in Vibrio cholerae non-O1 using the polymerase chain reaction (1995)
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 125 (1995), S. 0 
    Details
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract The polymerase chain reaction has been used to differentiate the gene which encodes the toxin co-regulated pili (tcpA) of the El Tor and classical biotypes of Vibrio cholerae O1. The same PCR primers were applied to strains belonging to non-O1 serogroups that produced cholera toxin. The size of fragment amplified was either identical to the tcpA of biotype El Tor (471 bp) or to the tcpA of biotype classical (617 bp). All strains belonging to the novel epidemic serogroup O139 generated a 471-bp fragment identical to El Tor tcpA. The present study suggests that there may be an association between non-O1 serogroup and tcpA type.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1574-6968.1995.tb07359.x
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