ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
Filter
  • Organic Chemistry  (3)
  • Binding Sites  (2)
  • 1,2,4,5-Tetrazines  (1)
  • Wiley-Blackwell  (4)
  • American Association for the Advancement of Science (AAAS)  (2)
  • American Association for the Advancement of Science
  • American Chemical Society
  • American Physical Society
  • American Physical Society (APS)
  • Institute of Physics
  • 2005-2009
  • 2000-2004
  • 1990-1994  (6)
  • 1980-1984
  • 1970-1974
  • 1935-1939
  • 1994  (6)
Sammlung
Schlagwörter
Verlag/Herausgeber
  • Wiley-Blackwell  (4)
  • American Association for the Advancement of Science (AAAS)  (2)
  • American Association for the Advancement of Science
  • American Chemical Society
  • American Physical Society
    • +
Erscheinungszeitraum
  • 2005-2009
  • 2000-2004
  • 1990-1994  (6)
  • 1980-1984
  • 1970-1974
    • +
Jahr
  • 1
    Digitale Medien
    Digitale Medien
    Wanzlick-Carbene in der [4 + 1]-Cycloaddition mit Bis(methylthio)- und Bis(trifluormethyl)-1,2,4,5-tetrazin (1994)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 127 (1994), S. 1803-1806 
    Details
    ISSN: 0009-2940
    Schlagwort(e): Singlet carbenes ; [4 + 1] Cycloadditions ; 1,2,4,5-Tetrazines ; SEAr reactions, intramolecular ; Chemistry ; Inorganic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Wanzlick Carbenes in the [4 + 1] Cycloaddition Reaction with Bis(methylthio)- and Bis(trifluoromethyl)-1,2,4,5-tetrazineThe 3,6-disubstituted 1,2,4,5-tetrazines 3 and 4 have been submitted to a [4 + 1] cycloaddition reaction with the nucleophilic singlet carbenes (Wanzlick carbenes) 2a-d, which are generated from the precursors 1a-d. With 3 as diazadiene the expected spiro compounds 6a-d are formed. In contrast to this presumed two-step reaction sequence of 3, with the tetrazine 4 the cascade cycloaddition/cycloelimination is surprisingly followed by an intramolecular electrophilic aromatic substitution to yield the chiral tetracyclic compounds of type 8 with high diastereoselectivity. The crystal structure of 8d has been determined by X-ray diffraction methods.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/cber.19941270933
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 2
    Digitale Medien
    Digitale Medien
    (Z)-1,1-dichloro-2-(4-benzyloxyphenyl)-2,3-bis(4-methoxyphenyl)cyclopropane: The synthesis and enantiomeric separation of an antitumor agent (1994)
    New York, NY [u.a.] : Wiley-Blackwell
    Chirality 6 (1994), S. 41-45 
    Details
    ISSN: 0899-0042
    Schlagwort(e): chiral HPLC ; Chiralpak AD ; amylose carbamate stationary phase ; antiestrogen ; breast cancer ; dichlorotriarylcyclopropane ; Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: (Z)-1,1-Dichloro-2-(4-benzyloxyphenyl)-2,3-bis(4-methoxyphenyl)cyclopropane (5), a potential antitumor agent designed to treat breast cancer, was prepared in three steps. A stereospecific palladium-catalyzed cross coupling reaction which provided the intermediate (Z)-triaryl alkene 4 was a crucial step in the synthesis. Makosza phase transfer reaction on 4 gave the enantiomeric (Z)-dichlorocyclopropane derivatives 5 which were resolved by semipreparative HPLC on a chiral stationary phase consisting of amylose tris-3,5-dimethylphenyl carbamate coated on silica gel. © 1994 Wiley-Liss, Inc.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/chir.530060108
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 3
    Digitale Medien
    Digitale Medien
    Synthese, Strukturaufklärung und Reaktionen trans-verknüpfter 3, 6-Anhydro-1, 2-O-isopropyliden-α-D-hexofuranosen (1994)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1994 (1994), S. 337-346 
    Details
    ISSN: 0170-2041
    Schlagwort(e): Carbohydrates ; Hexofuranoses ; 3, 6-Anhydro-D-hexofuranoses ; Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Synthesis, Structure Elucidation and Reactions of trans-Fused 3, 6-Anhydro-1, 2-O-isopropylidene-α-D-hexofuranosesUnexpectedly, the reaction of 1, 2-O-isopropylidene-5, 6-di-O-(p-tolylsulfonyl)-α-D-allofuranose (7) with KCN in ethanol yielded the first trans-fused 3,6-anhydro-hexofuranose 10. Besides by spectroscopic evidence the structure of 10 was proved by transformation to the tosylated acetal 13 which could also be obtained via an independent route. Further reactions of 10 all resulted in opening of the strained ring system yielding acetals (18-22). By blocking the 5-position with the alkali-resistant ether function this cyclization could also be achieved by more common reagents like NaH in DMF (32). - By applying this procedure to the corresponding α-D-galactofuranose derivative 41 3,6-anhydro-α-D-galactofuranose 42 could also be obtained albeit in low yield. For comparison purposes the 3,6-anhydro-α-D-gulo derivative 47 was synthesized from easily accessible 44.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jlac.199419940405
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 4
    Digitale Medien
    Digitale Medien
    Synthesis of doubly labeled enantiomerically pure (R)-mevalonolactone from lactic and malic acid (1994)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1994 (1994), S. 167-174 
    Details
    ISSN: 0170-2041
    Schlagwort(e): (R)-Mevalonolactone ; Isotopic labeling, 13C, 1H ; Chirality, self-reproduction of ; Lactic acid ; Malic acid ; Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Enantiomerically pure 13C- and 1H-labeled (R)-mevalonolactones are prepared from (S)-malic and/or (S)-lactic acid by Seebachs methodology of self-reproduction of chirality. The two reaction pathways are complementary in the possibilities of multiple isotopic labeling. The labeling potential is exemplified by the synthesis of a doubly 13C, 1H-labeled, one 13C-, and one 1H-labeled mevalonolactone.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jlac.199419940210
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 5
    facet.materialart.
    Unbekannt
    The structure of flavocytochrome c sulfide dehydrogenase from a purple phototrophic bacterium (1994)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1994-10-21
    Beschreibung: The structure of the heterodimeric flavocytochrome c sulfide dehydrogenase from Chromatium vinosum was determined at a resolution of 2.53 angstroms. It contains a glutathione reductase-like flavin-binding subunit and a diheme cytochrome subunit. The diheme cytochrome folds as two domains, each resembling mitochondrial cytochrome c, and has an unusual interpropionic acid linkage joining the two heme groups in the interior of the subunit. The active site of the flavoprotein subunit contains a catalytically important disulfide bridge located above the pyrimidine portion of the flavin ring. A tryptophan, threonine, or tyrosine side chain may provide a partial conduit for electron transfer to one of the heme groups located 10 angstroms from the flavin.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chen, Z W -- Koh, M -- Van Driessche, G -- Van Beeumen, J J -- Bartsch, R G -- Meyer, T E -- Cusanovich, M A -- Mathews, F S -- GM-20530/GM/NIGMS NIH HHS/ -- GM-21277/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1994 Oct 21;266(5184):430-2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7939681" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Binding Sites ; Chromatium/*enzymology ; Computer Graphics ; Crystallography, X-Ray ; Cytochrome c Group/*chemistry ; Electron Transport ; Flavin-Adenine Dinucleotide/metabolism ; Hydrogen Bonding ; Models, Molecular ; Oxidoreductases/*chemistry ; Protein Conformation ; Protein Structure, Secondary
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    AKTUELLE ARTIKEL
  • 6
    facet.materialart.
    Unbekannt
    A protein phosphatase 2C involved in ABA signal transduction in Arabidopsis thaliana (1994)
    American Association for the Advancement of Science (AAAS)
    Details
    Publikationsdatum: 1994-06-03
    Beschreibung: The plant hormone abscisic acid (ABA) mediates various responses such as stomatal closure, the maintenance of seed dormancy, and the inhibition of plant growth. All three responses are affected in the ABA-insensitive mutant abi1 of Arabidopsis thaliana, suggesting that an early step in the signaling of ABA is controlled by the ABI1 locus. The ABI1 gene was cloned by chromosome walking, and a missense mutation was identified in the structural gene of the abi1 mutant. The ABI1 gene encodes a protein with high similarity to protein serine or threonine phosphatases of type 2C with the novel feature of a putative Ca2+ binding site. Thus, the control of the phosphorylation state of cell signaling components by the ABI1 product could mediate pleiotropic hormone responses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meyer, K -- Leube, M P -- Grill, E -- New York, N.Y. -- Science. 1994 Jun 3;264(5164):1452-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Plant Sciences, Swiss Federal Institute of Technology, Zurich.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8197457" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Abscisic Acid/*pharmacology ; Amino Acid Sequence ; Arabidopsis/enzymology/genetics/*metabolism ; *Arabidopsis Proteins ; Binding Sites ; Calcium/metabolism ; Chromosome Walking ; Cloning, Molecular ; Genes, Plant ; Genetic Markers ; Molecular Sequence Data ; Mutation ; Phosphoprotein Phosphatases/chemistry/genetics/*metabolism ; Plants, Genetically Modified ; *Signal Transduction
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Publiziert von American Association for the Advancement of Science (AAAS)
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    AKTUELLE ARTIKEL
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...