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  • AERODYNAMICS  (3)
  • Chemistry  (3)
  • Female
  • 1990-1994  (6)
  • 1991  (6)
  • 1
    Electronic Resource
    Electronic Resource
    Imaging as a tool for improving length and accuracy of sequence analysis in automated fluorescence-based DNA sequencing (1991)
    Weinheim : Wiley-Blackwell
    Electrophoresis 12 (1991), S. 3-11 
    Details
    ISSN: 0173-0835
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: A new method of signal analysis for automated fluorescence-based DNA sequencing is presented. Signal resolution is a limiting factor in obtaining accurate sequence information beyond 400-450 nucleotides per gel lane. We have developed a computer program for the imaging of DNA bands in sequencing gels. The image analysis shows that distortions in the shapes of the bands decrease resolution of peaks observed in the standard data plots. Reconstruction of the undistorted band shape prior to signal analysis substantially improves the resolution of peaks and may improve the accuracy and length of the contiguous sequence read. Image analysis identified other factors limiting the accuracy and length of automated DNA sequence analysis and provided a tool for evaluating various remedies. Our techniques should also be applicable in other systems, for example, in gel electrophoresis of proteins and DNA restriction fragments, and in scranning densitometry.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/elps.1150120103
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    NMR analysis of fluorinated corticosteroids related to fluocinonide: Detection of long-range 1H-19F couplings using the heteronuclear equivalent of the COSY experiment (1991)
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 29 (1991), S. 387-397 
    Details
    ISSN: 0749-1581
    Keywords: 1H NMR ; 19F Corticosteroids ; 1H-19F long-range coupling ; Heteronuclear COSY ; 1H-19F 2D correlation ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The analysis of the 1H and 19F NMR spectra of the corticosteroid fluocinonide and five related steroids is reported. The 500 MHz 1H NMR spectra revealed several previously undetected long-range 1H-19F coupling constants. These couplings were assigned by the application of the heteronuclear equivalent of the COSY pulse sequence. The fluorine substituent effects and long-range heteronuclear couplings were examined in relation to structures derived from molecular mechanics (MMX) calculations.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrc.1260290417
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Evaluation of secondary lubricants for rigid PVC extrusion (1991)
    Brookfield, Conn. : Wiley-Blackwell
    Journal of Vinyl and Additive Technology 13 (1991), S. 148-150 
    Details
    ISSN: 0193-7197
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A common system of primary lubricants in rigid PVC extrusion compounds is calcium stearate plus paraffin wax. Secondary lubricants are frequently added to this system at low concentrations with the intention of improving such properties as metal release, thermal stability, plateout, extrudate surface appearance, etc. This paper discusses the results of laboratory studies designed to evaluate the contribution to these properties of two commonly used secondary lubricants: AC629A, an oxidized low molecular weight polyethylene, and K175, an acrylic “lubricating processing aid.” Surprisingly, the testing showed little improvement in performance when these auxiliary lubricants were added.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/vnl.730130308
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  • 4
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    Application of the Galerkin/least-squares formulation to the analysis of hypersonic flows. I - Flow over a two-dimensional ramp (1991)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: An FEM for the compressible Navier-Stokes equations is introduced. The discretization is based on entropy variables. The methodology is developed within the framework of a Galerkin/least-squares formulation to which a discontinuity-capturing operator is added. Results for three test cases selected among those of the Workshop on Hypersonic Flows for Reentry Problems are presented.
    Keywords: AERODYNAMICS
    Type: In: Hypersonic flows for reentry problems. Vol. 2 (A93-42576 17-02); p. 181-200.
    Format: text
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  • 5
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    Application of the Galerkin/least-squares formulation to the analysis of hypersonic flows. II - Flow past a double ellipse (1991)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: A finite element method for the compressible Navier-Stokes equations is introduced. The discretization is based on entropy variables. The methodology is developed within the framework of a Galerkin/least-squares formulation to which a discontinuity-capturing operator is added. Results for four test cases selected among those of the Workshop on Hypersonic Flows for Reentry Problems are presented.
    Keywords: AERODYNAMICS
    Type: In: Hypersonic flows for reentry problems. Vol. 2 (A93-42576 17-02); p. 427-450.
    Format: text
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  • 6
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    A new finite element formulation for computational fluid dynamics. X - The compressible Euler and Navier-Stokes equations (1991)
    In:  Other Sources
    Details
    Publication Date: 2019-07-12
    Description: A space-time element method is presented for solving the compressible Euler and Navier-Stokes equations. The proposed formulation includes the variational equation, predictor multi-corrector algorithms and boundary conditions. The variational equation is based on the time-discontinuous Galerkin method, in which the physical entropy variables are employed. A least-squares operator and a discontinuity-capturing operator are added, resulting in a high-order accurate and unconditionally stable method. Implicit/explicit predictor multi-corrector algorithms, applicable to steady as well as unsteady problems, are presented; techniques are developed to enhance their efficiency. Implementation of boundary conditions is addressed; in particular, a technique is introduced to satisfy nonlinear essential boundary conditions, and a consistent method is presented to calculate boundary fluxes. Numerical results are presented to demonstrate the performance of the method.
    Keywords: AERODYNAMICS
    Type: Computer Methods in Applied Mechanics and Engineering (ISSN 0045-7825); 89; 3-Jan; 141-219
    Format: text
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    NASA TECHNICAL REPORTS
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