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  • 1
    Electronic Resource
    Electronic Resource
    Ewing's tumor X mouse hybrids expressing the MIC2 antigen: analyses using fluorescence CDD-banding and non-isotopic ISH (1992)
    Springer
    Human genetics 〈Berlin〉 88 (1992), S. 273-278 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary We present a highly sensitive method that has been applied to map the chromosomal origin of the prominent cell surface antigen of Ewing's tumor cells recognized by monoclonal antibody HBA-71. The technique allows an unambiguous identification of human chromosomal material in interspecific cell hybrids. This is achieved by fluorescent in situ hybridization of biotinylated total human DNA, followed by high resolution fluorescence banding with the chromomycin/distamycin/ DAPI triple stain. An advantage of this method is that all signals can be visualized in one single operation by simply switching the appropriate filter blocks. The protocol has proved extremely useful in gene mapping by means of interspecific cell hybrids, a technique that depends on the accurate and unambiguous recognition of the relevant (e.g., human) genetic material in the clonal genome. Our studies confirm that this antigen is the product of the MIC2 gene, which is so far the only well-studied pseudoautosomal gene in man, and which is located on the short arms of chromosomes X and Y. Furthermore, no influence of the Ewing's tumor-specific translocation t(11;22) on MIC2 expression could be discerned.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00197258
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  • 2
    Electronic Resource
    Electronic Resource
    Density dependent interactions between VA mycorrhizal fungi and even-aged seedlings of two perennial Fabaceae species (1992)
    Springer
    Oecologia 91 (1992), S. 281-287 
    Details
    ISSN: 1432-1939
    Keywords: Vesicular-arbuscular mycorrhizas ; Densitydependence ; Plant population dynamics ; Resource depletion ; Phosphorus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The interaction of density and mycorrhizal effects on the growth, mineral nutrition and size distribution of seedlings of two perennial members of the Fabaceae was investigated in pot culture. Seedlings of Otholobium hirtum and Aspalathus linearis were grown at densities of 1, 4, 8 and 16 plants per 13-cm pot with or without vesicular-arbuscular (VA) mycorrhizal inoculum for 120 days. Plant mass, relative growth rates, height and leaf number all decreased with increasing plant density. This was ascribed to the decreasing availability of phosphorus per plant as density increased. O. hirtum was highly dependent on mycorrhizas for P uptake but both mycorrhizal and non-mycorrhizal A. linearis seedlings were able to extract soil P with equal ease. Plant size distribution as measured by the coefficient of variation (CV) of shoot mass was greater at higher densities. CVs of mycorrhizal O. hirtum plants were higher than those of non-mycorrhizal plants. CVs of the facultatively mycorrhizal A. linearis were similar for both mycorrhizal and non-mycorrhizal plants. Higher CVs are attributed to resource preemption by larger individuals. Individuals in populations with high CVs will probably survive stress which would result in the extinction of populations with low CVs. Mass of mycorrhizal plants of both species decreased more rapidly with increasing density than did non-mycorrhizal plant mass. It is concluded that the cost of being mycorrhizal increases as plant density increases, while the benefit decreases. The results suggest that mycorrhizas will influence density-dependent population processes of faculative and obligate mycorrhizal species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00317797
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  • 3
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of S(+)- and R(−)-ibuprofen in volunteers and first clinical experience of S(+)-ibuprofen in rheumatoid arthritis (1990)
    Springer
    European journal of clinical pharmacology 38 (1990), S. 493-497 
    Details
    ISSN: 1432-1041
    Keywords: ibuprofen ; rheumatoid arthritis ; enantiomer ; stereoselectivity ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary S(+)-, R(−)- or racemic ibuprofen was administered orally to volunteers in doses of 150 mg, 300 mg and 500 mg pure S(+)-, 300 mg pure R(−)- and 600 mg racemic ibuprofen. The pharmacokinetic parameters in humans showed that S(+)-ibuprofen was not inverted to R(−)-ibuprofen, whereas R(−)-ibuprofen was inverted to S(+)-ibuprofen to a variable degree. S(+)-ibuprofen and R(−)-ibuprofen given alone more rapidly reached significantly higher maximal plasma concentrations than after the same doses of the racemic compound. The elimination half-lives and clearance values for all three forms of ibuprofen were comparable. The mean residence time of S(+)-ibuprofen after R(−)- and racemic ibuprofen was significantly longer than after administration of the pure S(+)-enantiomer. Judged by the AUC, the bioavailability of S(+)-ibuprofen was independent of the dose within the range tested. Administration of S(+)-ibuprofen to 6 rheumatic patients showed that the pharmacokinetic behaviour of S(+)-ibuprofen in patients was similar to that found in volunteers. S(+)-ibuprofen proved to be an effective analgesic antirheumatic drug in the dose range 1 to 1.5 g/day.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02336690
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  • 4
    Electronic Resource
    Electronic Resource
    Physiological aspects of glyphosate degradation in Alcaligenes spec. strain GL (1990)
    Springer
    Archives of microbiology 153 (1990), S. 146-150 
    Details
    ISSN: 1432-072X
    Keywords: Alcaligenes spec. GL ; Phosphonate metabolism ; Glyphosate ; Sarcosine ; Phosphate starvation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Alcaligenes spec. strain GL (IMET 11314) is able to grow on glyphosate (N-[phosphonomethyl]glycine) and other phosphonates as sole source of phosphorus. Degradation of glyphosate to inorganic phosphate and sarcosine by this strain is subject to several regulatory principles. While uptake and dephosphonation of glyphosate are regulated by Pi starvation, the intensity of glyphosate degradation is also controlled by the cellular ability to utilize the C-skeleton derived from glyphosate. Depending on the external concentration of glyphosate, the liberated sarcosine is differentially metabolised. Utilization of the sarcosine moiety and complete incorporation of 3-[14C]-label of glyphosate into cellular material occur only in cultures adapted to higher concentrations (5 mM) of the herbicide. At low concentrations of glyphosate (1 mM) only the Pi required by the growing cultures is utilized but not the sarcosine. Initially high rates of glyphosate uptake obtained after Pi-starvation decrease in the presence of low glyphosate concentrations. It is suggested that uptake and metabolism of glyphosate are connected with the expression of the sarcosine metabolizing capacity of the Alcaligenes cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00247812
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  • 5
    Electronic Resource
    Electronic Resource
    Internal structure rebuilding reactions of crystalline and amorphous solids (1992)
    Springer
    Journal of thermal analysis and calorimetry 38 (1992), S. 131-139 
    Details
    ISSN: 1572-8943
    Keywords: amorphous solids ; crystalline ; structural mechanism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Es werden Strukturmechanismen von internen thermischen Reaktionen von Dehydratation und Dehydroxylierung sowie der Kristallisierung der entstehenden amorphen Reaktionsprodukte betrachtet. Dabei handelt es sich um mehrstufige Prozesse, die über kleine translative Verschiebungen von polimerisierten Elementen des Anionennetzwerkes und durch Diffusionsverschiebung von Kationen ablaufen. Dies ist der Weg zum Gleichgewichtszustand mit dem geringsten Energieverbrauch und der niedrigsten, zu überwindenden Energiebarriere.
    Notes: Abstract Structural mechanism of the internal thermal reactions of dehydration and dehydroxylation as of solids well as crystallization of their amorphous products and glasses are considered. They are multi-stage processes, realized through small translative displacements of polymerized anion network elements and diffusional shift of cations. It is the way to equilibrium state of the lowest energy consumption and the least energetic barrier to overcome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02109113
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  • 6
    Electronic Resource
    Electronic Resource
    First record of Crustacea Malacostraca from fresh waters in the Canary Islands (1990)
    Springer
    Hydrobiologia 206 (1990), S. 53-59 
    Details
    ISSN: 1573-5117
    Keywords: Tenerife ; epigean fresh water ; Amphipoda ; Rhipidogammarus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Resumen Crustacea Malacostraca era hasta ahora desconocida de las aguas dulces de las Islas Canarias. Una nueva especie de anfípodo, Rhipidogammarus rheophilus, ha sido recientemente descubierto de fuentes y manantiales de Tenerife.
    Notes: Abstract Crustacea Malacostraca were hitherto unknown from fresh waters of the Canary Islands. A new species of Amphipoda, Rhipidogammarus rheophilus, has recently been discovered in springs and spring brooks in Tenerife.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00018969
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  • 7
    Electronic Resource
    Electronic Resource
    Analysis of Taylor vortex flow by means of laser light scattering (1992)
    Springer
    Rheologica acta 31 (1992), S. 274-282 
    Details
    ISSN: 1435-1528
    Keywords: Light-scattering ; flowing polymer solution ; dilute polystyrene solution ; Taylor-vortex ; solvent power
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Abstract Rheological measurements and light-scattering experiments were performed on dilute solutions of high molecular polystyrene. We are able to describe the orientation behavior of chain molecules under shear flow by means of light-scattering. Beyond that these investigations of light-scattering of flowing polymer solutions are an useful and suitable tool for detection and characterization of Taylor vortex formation. We can estimate the appearance of these hydrodynamic instabilities, which overlay the laminar main flow and we can observe a typical influence of the solvent power on it.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00366506
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  • 8
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    Measurement ofπ0π0production in two-photon collisions (1990)
    American Physical Society
    Details
    Publication Date: 1990-06-01
    Print ISSN: 0556-2821
    Electronic ISSN: 1089-4918
    Topics: Physics
    Published by American Physical Society
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  • 9
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    Physiological aspects of glyphosate degradation in Alcaligenes spec. strain GL (1990)
    Springer
    Details
    Publication Date: 1990-01-01
    Print ISSN: 0302-8933
    Electronic ISSN: 1432-072X
    Topics: Biology
    Published by Springer
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  • 10
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    First record of Crustacea Malacostraca from fresh waters in the Canary Islands (1990)
    Springer
    Details
    Publication Date: 1990-10-01
    Print ISSN: 0018-8158
    Electronic ISSN: 1573-5117
    Topics: Biology
    Published by Springer
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