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  • GEOPHYSICS  (168)
  • Cell & Developmental Biology  (109)
  • 1985-1989  (277)
  • 1970-1974
  • 1935-1939
  • 1988  (277)
Collection
Keywords
Publisher
Years
  • 1985-1989  (277)
  • 1970-1974
  • 1935-1939
Year
  • 1
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    The 8 February 1986 magnetospheric compression event - Observations of simultaneous magnetospheric leakage and specularly reflected solar wind ions (1988)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: Multi-satellite observations of energetic particle were made during the magnetospheric compression event of February 8, 1986. In the upstream region in the interplanetary medium (IPM) observations were made of magnetospheric leakage particles and specularly reflected solar wind ions.
    Keywords: GEOPHYSICS
    Type: Advances in Space Research (ISSN 0273-1177); 8; 9-10,
    Format: text
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    NASA TECHNICAL REPORTS
  • 2
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    The CDAW-8 substorm event on 28 January 1983 - A detailed global study (1988)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: A small, isolated substorm with an expansion phase onset at 0739 UT on January 28, 1983 was well observed by ground-based instrumentation as well as by low- and high-altitude spacecraft. Because of the comprehensive nature of the data coverage, including ISEE-3 identification of plasmoid signatures in the deep tail (about 220 earth radii) associated with the substorm, a detailed timeline of the growth, expansion, and recovery phases of the substorm can be provided. The plasma, energetic particle, and field signatures at ISEE-3 are considered within the framework of the near-earth data. Quantitative estimates of substorm energy input and output relationships are made for this case, and the timing and physical dimensions of the deep tail disturbance implied are evaluated by the global observations available.
    Keywords: GEOPHYSICS
    Type: Advances in Space Research (ISSN 0273-1177); 8; 9-10,; 113-115
    Format: text
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    NASA TECHNICAL REPORTS
  • 3
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    The radial and longitudinal propagation characteristics of substorm injections (1988)
    In:  Other Sources
    Details
    Publication Date: 2019-07-12
    Description: This paper presents a statistical study of the radial and azimuthal propagation of substorm effects in the near-geosynchronous magnetotail. Data from five spacecraft (AMPTE/CCE, 1979-053, 1982-019, GOES-5, and GOES-6) have been used in the study. Since CCE has an apogee of 8.8 earth radii, those data allow for the study of both the radial and azimuthal propagation characteristics of substorm events. A list of ion injections was compiled from CCE energetic particle data obtained in 1985 and 1986. Those injections are dispersionless over an energy range of 25 to 285 keV on a 72-sec time scale. Dispersionless injections during which 1979-053 or 1982-019 were on the nightside in close longitudinal proximity to CCE were selected for the study. The most significant correlation in the data is between the local time separation between any two spacecraft and the time delay between the local onsets.
    Keywords: GEOPHYSICS
    Type: Advances in Space Research (ISSN 0273-1177); 8; 9-10; 91-95
    Format: text
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    NASA TECHNICAL REPORTS
  • 4
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    An observation of atmospheric gravity wave cause and effect during October 1985 WAGS campaign (1988)
    In:  Other Sources
    Details
    Publication Date: 2019-07-12
    Description: Moderate geomagnetic activity followed by a large scale TID was observed in Europe and eastern North America near 1200 UT on October 18, 1985 during the Worldwide Atmospheric Gravity Wave Study. The speed and direction of the TID are estimated, suggesting that it was caused by an atmospheric gravity wave expanding from a localized source over the Arctic Ocean. Auroral imaging shows that the source region was located near the westward edge of an expanding auroral bulge and may have been associated with a westward traveling surge. The TID periods increased with distance from the source region and the largest TID amplitudes were seen along a line perpendicular to the orientation of the auroral oval.
    Keywords: GEOPHYSICS
    Type: Radio Science (ISSN 0048-6604); 23; 919-930
    Format: text
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    NASA TECHNICAL REPORTS
  • 5
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    Studies of high latitude mesospheric turbulence by radar and rocket. II - Measurements of small scale turbulence (1988)
    In:  Other Sources
    Details
    Publication Date: 2019-07-12
    Description: Measurements of mesospheric small scale turbulence and associated larger scale wave structures were obtained from rocket probe flights during equinox in spring 1985. The measurements were verified by data from the mesosphere-stratosphere-troposphere radar at Poker Flat, Alaska. Electron density irregularities down to an altitude of about 62 km and fluctuations in positive ion density in the altitude region from 50 to 90 km were measured. Turbulence in the inertial subrange was observed at heights where the fluctuations generally were largest. Measurement of background electron density exhibited gradients relative to the monotonically increasing density profile, suggesting the presence of large amplitude wave motions transporting the plasma by mixing. The radar detected the occurrence of 1-3 km wavelike perturbations superimposed on a 7-km wave in the wind velocity field. It is suggested that the 1-3 km waves are more important in the transport of energy and momentum and in the production of turbulence in the lower mesosphere.
    Keywords: GEOPHYSICS
    Type: Journal of Atmospheric and Terrestrial Physics (ISSN 0021-9169); 50; 963-976
    Format: text
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    NASA TECHNICAL REPORTS
  • 6
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    Auroral energy deposition rate, characteristic electron energy, and ionospheric parameters derived from Dynamics Explorer 1 images (1988)
    In:  Other Sources
    Details
    Publication Date: 2019-07-12
    Description: Auroral images obtained by the Spin Scan Auroral Imager (SAI) aboard the DE-1 satellite were used to derive auroral energy deposition rate, characteristic electron energy, and ionospheric parameters. The principles involved in the imaging technique and the physical mechanisms that underlie the relationship between the spectral images and the geophysical parameters are discussed together with the methodology for implementing such analyses. It is shown that images obtained with the SAI provide global parameters at 12-min temporal resolution; the spatial resolution is limited by the field of view of a pixel. The analysis of the 12-min images presented yielded a representation of ionospheric parameters that was better than can be obtained using empirical models based on local measurements averaged over long periods of time.
    Keywords: GEOPHYSICS
    Type: Journal of Geophysical Research (ISSN 0148-0227); 93; 12841-12
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    NASA TECHNICAL REPORTS
  • 7
    Electronic Resource
    Electronic Resource
    A polypeptide growth inhibitor isolated from lactating bovine mammary gland (MDGI) is a lipid-carrying protein (1988)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 38 (1988), S. 199-204 
    Details
    ISSN: 0730-2312
    Keywords: fatty acid-binding protein ; mechanism of action ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Mammary-derived growth inhibitor (MDGI), a polypeptide growth inhibitor isolated from lactating bovine mammary tissue, previously shown to have extensive sequence homology with fatty acid-binding proteins, was demonstrated to meet the criteria of a fatty acid-binding protein. The protein was found to bind [3H]palmitic acid in a saturable manner and to be complexed with endogeneous free fatty acids. [3H]palmitic acid, when bound to the protein, was more rapidly taken up by the target cells (human mammary carcinoma cells [MaTu]) than was free [3H]palmitic acid, suggesting a lipid carrier function for the inhibitor. It is suggested that the fatty acid-binding properties of MDGI may relate to its ability to inhibit cell growth in vitro and to regulate other cellular functions.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240380307
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  • 8
    Electronic Resource
    Electronic Resource
    Electrophoretic analysis of four high molecular weight sialoglycoproteins produced by metastatic human colon carcinoma cells (1988)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 37 (1988), S. 1-9 
    Details
    ISSN: 0730-2312
    Keywords: colon cancer ; metastasis ; mucins ; electrophoresis ; lectins ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: We have found that polyacrylamide gel electrophoresis in 3% gels in the presence of sodium dodecyl sulfate is suitable for the separation of cellular glycoproteins having molecular weights ranging from 200,000 to 1,000,000. The gels secured on a rigid support (Gelbond) allow blotting techniques with lectins and antibodies for the detection of glycoproteins. Using these methods we have separated lysates of HT-29 human colon carcinoma cells and detected at Jeast four distinct high molecular weight Sialoglycoproteins having molecular weights of 900,000, 740.000, 560,000, and 450,000. The expression of the 9000,000 component, as revealed by wheat germ agglutinin binding, was much higher in a subline of HT-29 cells established from liver metastases in a nude mouse than it was in the parental cells. The relative intensity of wheat germ agglutinin binding to these four sialoglycoprotein components differs depending upon their growth phase in vitro. These glycoproteins were also detectable by the binding of peanut agglutinin, provided the glycoproteins were previously treated in the gels with mild acid to remove the sialic acid from their carbohydrate chains, suggesting that mucin-type carbohydrate chains are present on these glycoproteins. The same set of glycoproteins can be detected by metabolic labeling of the cells with [3H] glucosamine in tissue culture. Very similar glycoprotein profiles are revealed by metabolic labeling of fresh colon carcinoma tissues with [3H] glucosamine in vitro.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240370102
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  • 9
    Electronic Resource
    Electronic Resource
    Loss of three major auto phosphorylation sites in the EGF receptor does not block the mitogenic action of EGF (1988)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 134 (1988), S. 421-428 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The EGF receptor cDNA has been transfected into receptor-negative Chinese hamster ovary (CHO) cells. A mutant cell line (CHO 11) was isolated that expresses a receptor of lower molecular weight than the EGF receptor from A431 cells (150,000 daltons compared to 170,000 daltons) and which appeared as a doublet on SDS-PAGE. By digestion of the receptor with endoglycosidase F it was shown that an altered pattern of glycosylation could not account for the smaller size of the protein, although it could explain the appearance of the CHO 11 receptor as a doublet protein. A deletion was located to the transfected cDNA and shown to involve the removal of coding sequences for the most C-terminal 20,000 daltons of the EGF receptor, which contains the three major autophosphoryation sites. Despite the loss of these sites the EGF receptor from CHO 11 cells binds EGF, demonstrates protein tyrosine kinase activity in response to EGF, and transduces a mitogenic signal. The CHO 11 receptor protein is still autophosphorylated on alternative tyrosine residues. We conclude that phosphorylation of the three tyrosines (P1, P2, and P3) in the C-terminal domain of the receptor is not required for signal transduction by the EGF receptor in these cells.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1041340313
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  • 10
    Electronic Resource
    Electronic Resource
    Induction of angiogenesis in vitro by vanadate, an inhibitor of phosphotyrosine phosphatases (1988)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 134 (1988), S. 460-466 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: We have previously shown that capillary endothelial cells grown on the surface of three-dimensional collagen gels can be induced to invade the underlying fibrillar matrix and to form capillary-like tubular structures in response to tumor-promoting phorbol esters or the angiogenic agent fibroblast growth factor (FGF). Since both phorbol esters and FGF stimulate phosphorylation of tyrosine residues, we treated endothelial cells with vanadate, an inhibitor of phosphotyrosine-specific phosphatases, to determine whether this agent could induce the expression of an anglogenic phenotype in these cells. We show here that vanadate stimulates endothelial cells to invade collagen matrices and to organize into characteristic tubules resembling those induced by FGF or phorbol esters. We have further observed that vanadate concomitantly stimulates endothelial cells to produce plasrninogen activators (PAs), proteolytic enzymes which are induced by phorbol esters and FGF, and which have been implicated in the neovascular response; this stimulation can be accounted for by an increase in the levels of urokinase-type PA and tissue type PA mRNA. These results suggest a role for tyrosine phosphorylation in the regulation of the angiogenic phenotype in capillary endothelial cells.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1041340318
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