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  • GEOPHYSICS  (2)
  • Life and Medical Sciences
  • pharmacokinetics
  • 1985-1989  (3)
  • 1930-1934
  • 1915-1919
  • 1986  (3)
Collection
Publisher
Years
  • 1985-1989  (3)
  • 1930-1934
  • 1915-1919
Year
  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 128 (1986), S. 402-412 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Fibronectin isolated from the conditioned medium of monolayer cultures of baby hamster kindey (BHK) cells and several ricin-resistant (Ric®) mutants derived from them express differences in N-glycosylation. The asparaginelinked oligosaccharides of BHK cell-derived fibronectin consist largely of complex chains, whereas hybrid and/or high-mannose chains are present in the fibronectins of mutant cell lines. The fibronectins exhibiting different glycosylation patterns are incorporated to similar extents into the cell-layer of human skin fibroblasts. In contrast, mutant cells retain significantly less endogenously produced fibronectin than BHK cells and also incorporate less human cellular fibronectin into a pericellular matrix. In vitro adhesion assays show that mutant cells attach to and spread relatively poorly on fibronectinor type IV collagen-coated substrata but interact as well as do BHK cells with a laminin substratum. These results indicate that asparagine-linked oligosaccharides of fibronectin are not required for the binding and incorporation of the molecule into cell layers, but, as constituents of other cellular glycoproteins, they do modulate the ability of BHK cells to interact with some matrix components.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2019-07-12
    Description: Substorm onsets, identified Pi 2 pulsations observed on the Air Force Geophysics Laboratory Magnetometer Network, are studied using magnetometer and electric field data from ISEE 1 as well as magnetometer data from the geosynchronous satellites GOES 2 and 3. The mid-latitude magnetometer data provides the means of both timing and locating the substorm onset so that the spacecraft locations with respect to the substorm current systems are known. During two intervals, each containing several onsets or intensifications, ISEE 1 observed field-aligned current signatures beginning simultaneously with the mid-latitude Pi 2 pulsation. Close to the earth broadband bursts of wave noise were observed in the electric field data whenever field-aligned currents were detected. One onset occurred when ISEE 1 and GOES 2 were on the same field line but in opposite hemispheres. During this onset ISEE 1 and GOES 2 saw magnetic signatures which appear to be due to conjugate field-aligned currents flowing out of the western end of the westward auroral electrojets. The ISEE 1 signature is of a line current moving westward past the spacecraft. During the other interval, ISEE 1 was in the near-tail region near the midnight meridian. Plasma data confirms that the plasma sheet thinned and subsequently expanded at onset. Electric field data shows that the plasma moved in the opposite direction to the plasma sheet boundary as the boundary expanded which implies that there must have been an abundant source of hot plasma present. The plasma motion was towards the center of the plasma sheet and earthwards and consisted of a series of pulses rather than a steady flow.
    Keywords: GEOPHYSICS
    Type: Journal of Geophysical Research (ISSN 0148-0227); 91; 121-134
    Format: text
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  • 3
    Publication Date: 2019-07-12
    Description: Fast magnetoacoustic waves can be ducted by plasma inhomogeneities such as the plasma sheet. As this ducting is dispersive an impulsive source will give rise to a well-defined, quasi-periodic wave packet with time-scales determined by the width of the inhomogeneity and characteristic speeds in the wave duct and surrounding medium. The duration of the wave packet depends upon the distance from the source. It is argued that an impulsive source in the plasma sheet at substorm onset will produce a wave packet near earth with characteristics similar to pi2 wave bursts and put this idea forward as a mechanism for the generation of pi2 pulsations.
    Keywords: GEOPHYSICS
    Type: Geophysical Research Letters (ISSN 0094-8276); 13; 373-376
    Format: text
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