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  • AERODYNAMICS  (120)
  • Chemical Engineering  (88)
  • Cell & Developmental Biology  (87)
  • Aircraft Design, Testing and Performance
  • GENERAL
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  • 1985-1989  (296)
  • 1955-1959
  • 1985  (296)
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  • 1985-1989  (296)
  • 1955-1959
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  • 1
    Publication Date: 2019-06-28
    Description: An investigation has been conducted in the Langley 16 Foot Transonic Tunnel to determine the weight flow measurement characteristics of a multiple critical Venturi system and the nozzle discharge coefficient characteristics of a series of convergent calibration nozzles. The effects on model discharge coefficient of nozzle throat area, model choke plate open area, nozzle pressure ratio, jet total temperature, and number and combination of operating Venturis were investigated. Tests were conducted at static conditions (tunnel wind off) at nozzle pressure ratios from 1.3 to 7.0.
    Keywords: AERODYNAMICS
    Type: NASA-TM-86405 , L-15960 , NAS 1.15:86405
    Format: application/pdf
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  • 2
    Publication Date: 2019-07-13
    Description: A conservative finite-volume difference scheme is developed for the potential equation to solve transonic flow about airfoils and bodies in an arbitrary channel. The scheme employs a mesh which is a nearly-conformal 'O' mesh about the airfoil and nearly orthogonal at the channel walls. The mesh extends to infinity upstream and downstream, where the mapping is singular. Special procedures are required to treat the singularities at infinity, including computation of the metrics near those points. Channels with exit areas different from inlet areas are solved; a body with a sting mount is an example of such a case.
    Keywords: AERODYNAMICS
    Type: Symposium on Numerical and Physical Aspects of Aerodynamic Flows; Jan 21, 1985 - Jan 24, 1985; Long Beach, CA
    Format: text
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  • 3
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 31 (1985), S. 1113-1120 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The concept of the trailing vortex introduced by van't Riet and Smith (1975) is used for evaluation of the mean velocity and intensity of periodic velocity fluctuations in the turbine impeller discharge flow. From the analysis of forces acting on the trailing vortex, it follows that geometric similarity in the impeller discharge flow can be expected for the Reynolds number range Re ε 〈1.5 × 104; 9.0 × 104〉 and for the radial distance up to one-tenth of the impeller diameter. The calculated profiles of mean velocity and intensity of periodic velocity fluctuations agree with published data and permit the declaration of boundary conditions for the impeller discharge flow for numerical modeling of turbulent fluid flow in turbine impeller agitated tanks.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 31 (1985), S. 170-174 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 31 (1985), S. 659-666 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The performance of a two-phase liquid-liquid continuous flow stirred tank reactor (CFSTR) was evaluated experimentally by simultaneous determination of dispersed phase drop size distribution and extraction efficienty as a function of reactor operating conditions. The results provided a basis against which predictions made by a previously developed simulation technique (Bapat et al., 1984) were compared. The close agreement between the experimental and the simulation results validates the drop rate models and the simulation algorithm employed in this work.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 28 (1985), S. 229-239 
    ISSN: 0730-2312
    Keywords: cell surface ; galactosyltransferase ; immunochemical localization ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: A cell surface UDP-galactose:N-acetylglucosamine galactosyltransferase (GT) has been directly localized on bovine cells in tissue culture by immunohistochemical techniques. A conventional rabbit heteroantiserum was prepared against an affinity-purified soluble form of GT from bovine milk, and a monospecific IgG fraction was isolated by affinity chromatography on a GT adsorbent. As demonstrated by indirect immunofluorescence, antigen to this antibody is present on the surface of all three bovine cell lines tested. It was uniformly distributed over the exposed membrane surface of fixed cells. Exposure of living cells to the anti-GT antibody resulted in its time-dependent aggregation in the plane of the membrane. Antigen (GT) was released from the membrane surface by trypsin digestion, and its reappearance required protein synthesis, since cycloheximide effectively prevented repopulation of the cell surface.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 25 (1985), S. 207-211 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The embrittlement of ductile polymers resulting from outdoor weathering or aging or from the application of brittle surface coatings is explained using fracture mechanics principles. It is shown that in order for surface embrittlement to occur, the brittle surface should have a dynamic stress intensity factor at the brittle/ductile interface that exceeds the arrest toughness of the ductile polymer. This phenomenon is modeled using duplex tensile specimens fabricated from poly(methylmethacrylate) (brittle layer) and polycarbonate (ductile substrate) as well as from styrene-acrylonitrile and acrylonitrile-butadiene-styrene copolymers.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 28 (1985), S. 15-21 
    ISSN: 0730-2312
    Keywords: procollagen conversion ; amino-terminal proteinases ; carboxy-terminal proteinases ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Conversion from procollagen to collagen is a specific process that is a requirement for proper alignment of collagen molecules to form functional fibers. This process is catalyzed by at least three structurally and functionally distinct enzymes cleaving collagen types I-III. The cleavage processes possibly taking place in the more recently discovered collagen types are not known to any extent at this time.Two amino-terminal proteinases, one cleaving type I and type II procollagens and the other cleaving type III procollagen, have been purified close to homogeneity, and the more unspecific activity of carboxy-terminal proteinase has been isolated from several tissues. In our experimental model, however, cleavage of the carboxy-terminal propeptides of types I and III procollagen is differently affected by lysine. This suggests the presence of at least two distinct enzymes for the removal of carboxyl-terminal propeptides.The regulation of the reaction process from procollagen to collagen is not well known at present. The importance of the phenomenon in terms of fibril formation, however, is demonstrated by several elegant studies in vitro; and certain genetic disorders in which this process is defective demonstrate the significance in vivo. Moreover, the factors shown to effect the cleavage process may be potentially beneficial in the treatment of the pathological processes with abnormal collagen accumulation such as fibrosis.In this paper we briefly review the current knowledge of the converting enzymes, including some very recent findings of our laboratory as well as the evidence presented for the biological significance of the conversion process.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 29 (1985), S. 373-379 
    ISSN: 0730-2312
    Keywords: encystment induction ; Acanthamoeba castellanii ; pinocytotic inhibition ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Monoclonal antibodies that bind a large molecular weight plasma membrane protein of Acanthamoeba castellanii cause the cells to differentiate. A different monoclonal antibody that binds specifically to the major plasma membrane protein has no effect upon cell division or differentiation. The induction of differentiation by the monoclonal antibodies requires a bivalent attachment, more than a single binding cycle of the antibody to the plasma membrane protein, does not require cell-cell contact, and appears to be mediated by an inhibition of pinocytosis. These results suggest one of two alternatives: either (1) this free living amoeba possesses a cell surface receptor that serves to initiate the differentiation process when stimulated, or (2) the specific plasma membrane antigen for the differentiation-inducing monoclonal antibodies is an essential component of the pinocytotic mechanism. While it seems more likely on the basis of available evidence that we are observing the biological effects of a cell surface receptor, either of the two alternative circumstances open up investigative areas of large significance.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The effect of glucagon and insulin on the incorporation of 1-14C-acetate into cholesterol and fatty acids and on the enzymes involved in the first steps of cholesterol synthesis (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, 3-hydroxy-3-methyl-glutaryl-coenzyme A synthase, and acetoacetyl-coenzyme A thiolase) was investigated. Isolated rat hepatocytes at different stages of fetal and postnatal development were employed. Data obtained show the appearance of hormonal control on the 18th day of fetal life, indicating the same pattern, as regards acetate incorporation and HMGCoA reductase prepared and assayed in the presence of NaF. On the contrary, HMGCoA reductase, prepared without NaF, HMGCoA synthase, and acetoacetyl CoA thiolase, does not appear to respond to hormonal stimulation. In the perinatal period, the hormonal effect is no longer detectable, probably because of a hormone resistance of this metabolic pathway.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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