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  • Blackwell Publishing Ltd  (2)
  • American Meteorological Society
  • Springer Science + Business Media
  • 2000-2004
  • 1985-1989  (2)
  • 1985  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Rank 'Em (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Teaching statistics 7 (1985), S. 0 
    Details
    ISSN: 1467-9639
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-9639.1985.tb00593.x
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  • 2
    Electronic Resource
    Electronic Resource
    GENETICS OF THE RAT CT SYSTEM: ITS APPARENT COMPLEXITY IS A CONSEQUENCE OF CROSS-REACTIVITY BETWEEN THE DISTINCT MHC CLASS I ANTIGENS RT1.C AND RT1.A (1985)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 12 (1985), S. 0 
    Details
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The rat CT antigens are a system of medial histocompatibility antigens linked to RT1, the rat major histocompatibility complex (MHC). They have aroused interest firstly because, despite their extreme serological weakness, they are targets for ‘unrestricted’ cytotoxic T lymphocytes (CTL); and secondly because they have appeared to represent a complex genetic system in terms both of the number of genetic loci involved and the number of distinguishable antigenic specificities expressed. The CT system was originally defined by the reactions of LEW anti-F344 (RT1l anti-RT1lvl) secondary in vitro CTL. These CTL reacted strongly on DA(RT1avl) targets, but much more weakly on AUG or PVG (RT1c) targets. We have used the recently derived RT1 recombinant rat strains PVG.R19 (RT1.AavlIavlCc) and PVG.R20 (RT1.AcIcCavl) to investigate the genetic control of this system. Contrary to previous interpretations, the results are consistent with a model in which CT is a single locus, which maps to the RTI.C region. In addition, our results demonstrate that there is cross-reactivity of anti-RT1C CTLs on RT1A products, and we suggest that the earlier placement of a CT locus in the RT1.A region was probably incorrect and a consequence of this cross-reactivity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1744-313X.1985.tb00836.x
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