Publikationsdatum:
1984-10-26
Beschreibung:
The presence of antibodies to lymphadenopathy-associated retrovirus (LAV) was determined by a radioimmunoprecipitation assay and by an enzyme-linked immunosorbent solid assay of sera from Zairian patients with the acquired immune deficiency syndrome (AIDS) in 1983. Thirty-five of 37 patients (94 percent) and 32 of 36 patients (88 percent), respectively, were seropositive by the two tests. In a control group of 26 patients, six (23 percent) showed positive results in these tests. Of these six control patients, five had clinically demonstrable infectious diseases and a low ratio of T4 to T8 lymphocytes. In addition, sera collected from a control group of Zairian mothers in 1980 were positive for LAV in 5 of 100 cases. Other serologic data suggest that LAV was present as early as 1977 in Zaire.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Brun-Vezinet, F -- Rouzioux, C -- Montagnier, L -- Chamaret, S -- Gruest, J -- Barre-Sinoussi, F -- Geroldi, D -- Chermann, J C -- McCormick, J -- Mitchell, S -- New York, N.Y. -- Science. 1984 Oct 26;226(4673):453-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6238406" target="_blank"〉PubMed〈/a〉
Schlagwort(e):
Acquired Immunodeficiency Syndrome/*immunology
;
Antibodies, Viral/*analysis
;
Democratic Republic of the Congo
;
Enzyme-Linked Immunosorbent Assay
;
Female
;
Humans
;
Lymphatic Diseases/*microbiology
;
Male
;
Radioimmunoassay
;
Retroviridae/*immunology
;
T-Lymphocytes, Helper-Inducer/cytology
;
T-Lymphocytes, Regulatory/cytology
Print ISSN:
0036-8075
Digitale ISSN:
1095-9203
Thema:
Biologie
,
Chemie und Pharmazie
,
Informatik
,
Medizin
,
Allgemeine Naturwissenschaft
,
Physik
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