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  • AIRCRAFT STABILITY AND CONTROL  (1)
  • Cloning, Molecular/methods  (1)
  • Humans
  • 2000-2004
  • 1980-1984  (2)
  • 1950-1954
  • 1982  (2)
  • 1
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    Isolation of human oncogene sequences (v-fes homolog) from a cosmid library (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-06-04
    Description: To define the human homolog (or homologs) of transforming sequences (v-fes gene) common to Gardner (GA) and Snyder Theilen (ST) isolates of feline sarcoma virus (FeSV), a representative library of human lung carcinoma DNA in a cosmid vector system was constructed. Three cosmid clones were isolated containing GA/ST FeSV v-fes homologous cellular sequences, within 32- to 42-kilobase cellular inserts representing 56 kilobases of contiguous human cellular DNA. Sequences both homologous to, and colinear with, GA or ST FeSV v-fes are distributed discontinuously over a region of up to 9.5 kilobases and contain a minimum of three regions of nonhomology representing probable introns. A thymidine kinase selection system was used to show that, upon transfection to RAT-2 cells, the human c-fes sequence lacked detectable transforming activity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Groffen, J -- Heisterkamp, N -- Grosveld, F -- Van de Ven, W -- Stephenson, J R -- N0I-CO-75380/CO/NCI NIH HHS/ -- New York, N.Y. -- Science. 1982 Jun 4;216(4550):1136-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6281890" target="_blank"〉PubMed〈/a〉
    Keywords: Bacteriophage lambda/genetics ; *Cell Transformation, Viral ; Cloning, Molecular/methods ; DNA Restriction Enzymes ; DNA, Recombinant ; Escherichia coli/genetics ; *Genes, Viral ; Humans ; Retroviridae/*genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    PAPER CURRENT
  • 2
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    Design criteria for flightpath and airspeed control for the approach and landing of STOL aircraft (1982)
    In:  CASI
    Details
    Publication Date: 2019-06-28
    Description: A flight research program was conducted to assess requirements for flightpath and airspeed control for glide-slope tracking during a precision approach and for flare control, particularly as applied to powered-lift, short takeoff and landing (STOL) aircraft. Ames Research Center's Augmentor Wing Research Aircraft was used to fly approaches on a 7.5 deg glide slope to landings on a 30 X 518 m (100 X 1700 ft) STOL runway. The dominant aircraft response characteristics determined were flightpath overshoot, flightpath-airspeed coupling, and initial flightpath response time. The significant contribution to control of the landing flare using pitch attitude was the short-term flightpath response. The limiting condition for initial flightpath response time for flare control with thrust was also identified. It is possible to define flying-qualities design criteria for glide-slope and flare control based on the aforementioned response characteristics.
    Keywords: AIRCRAFT STABILITY AND CONTROL
    Type: NASA-TP-1911 , NAS 1.60:1911 , A-8645
    Format: application/pdf
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    NASA TECHNICAL REPORTS
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