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  • METALLIC MATERIALS  (3)
  • Corpus Striatum/drug effects/*metabolism  (1)
  • 1980-1984  (4)
  • 1981  (4)
  • 1
    Publication Date: 1981-11-20
    Description: The hydroxylase cofactor, tetrahydrobiopterin, and its biosynthetic system are localized in dopaminergic nerve terminals in the striatum. This conclusion is based on the nearly equivalent loss of tyrosine hydroxylase and tetrahydrobiopterin and its initial biosynthetic enzyme, guanosine triphosphate cyclohydrolase, after injection of 6-hydroxydopamine into the substantia nigra. The role of the hydroxylase cofactor in the regulation of dopamine synthesis is reassessed.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Levine, R A -- Miller, L P -- Lovenberg, W -- New York, N.Y. -- Science. 1981 Nov 20;214(4523):919-21.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6117945" target="_blank"〉PubMed〈/a〉
    Keywords: Aminohydrolases/*metabolism ; Animals ; Biopterin/analogs & derivatives/*metabolism ; Corpus Striatum/drug effects/*metabolism ; Dopamine/*metabolism ; GTP Cyclohydrolase/*metabolism ; Hydroxydopamines/pharmacology ; Male ; Pteridines/*metabolism ; Rats ; Rats, Inbred Strains ; Substantia Nigra/drug effects/metabolism ; Tyrosine 3-Monooxygenase/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2019-06-28
    Description: A concept for enhanced protection of superalloys consists of adding an oxidation- and diffusion-resistant cermet layer between the superalloy and the outer oxidation-resistant metallic alloy coating. Such a duplex coating was compared with a physical-vapor-deposited (PVD) NiCrAlY coating in cyclic oxidation at 1150 C. The substrate alloy was MA 754 - an oxide-dispersion-strengthened superalloy that is difficult to coat. The duplex coating, applied by plasma spraying, outperformed the PVD coating on the basis of weight change and both macroscopic and metallographic observations.
    Keywords: METALLIC MATERIALS
    Type: NASA-TM-82687 , E-968
    Format: application/pdf
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  • 3
    Publication Date: 2019-06-28
    Description: A thermal barrier coating system for protecting metal surfaces at high temperature in normally corrosive environments is described. The thermal barrier coating system includes a metal alloy bond coating, the alloy containing nickel, cobalt, iron, or a combination of these metals. The system further includes a corrosion resistant thermal barrier oxide coating containing at least one alkaline earth silicate. The preferred oxides are calcium silicate, barium silicate, magnesium silicate, or combinations of these silicates.
    Keywords: METALLIC MATERIALS
    Format: application/pdf
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  • 4
    Publication Date: 2019-07-13
    Description: Recent activities of the Lewis Research Center are reviewed which are directed toward developing materials for rotating hot section components for aircraft gas turbines. Turbine blade materials activities are directed at increasing metal temperatures approximately 100 C compared to current directionally solidified alloys by use of oxide dispersion strengthening or tungsten alloy wire reinforcement of nickel or iron base superalloys. The application of thermal barrier coatings offers a promise of increasing gas temperatures an additional 100 C with current cooling technology. For turbine disk alloys, activities are directed toward reducing the cost of turbine disks by 50 percent through near net shape fabrication of prealloyed powders as well as towards improved performance. In addition, advanced alloy concepts and fabrication methods for dual alloy disks are being studied as having potential for improving the life of future high performance disks and reducing the amount of strategic materials required in these components.
    Keywords: METALLIC MATERIALS
    Type: NASA-TM-82626 , E-879 , Ann. Intern. Gas Turbine Conf.; Mar 08, 1981 - Mar 12, 1981; Houston, TX; United States
    Format: application/pdf
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