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  • Animals  (1)
  • Polymer and Materials Science
  • 2000-2004
  • 1990-1994
  • 1985-1989
  • 1975-1979  (2)
  • 1979  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 13 (1979), S. 407-422 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: In the present study the conditions leading to tight binding of human serum albumin to the Amberlite XAD-7 resin without the use of chemical coupling agents have been defined. Optimal binding (10.97 mm/kg dry XAD-7) was achieved at pH 5.0 and adsorption conformed to a Langmuir isotherm. Theoretical analysis of the data suggest adsorption of a monolayer of albumin which is suported by the absence of visual surface coating on scanning electron micrographs. Binding of human serum albumin was reduced when two chemical coupling agents, glutaraldehyde and carbodiimide were included in the human serum albumin solution, the elution of adsorbed HSA from the resins under severe flow conditions was reduced, and the amount eluted was minimal in all instances.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 1979-06-15
    Description: Rates of cerebral perfusion were obtained from measurements of the disappearance (wash-out) of oxygen-15 after in situ tissue activation with 45-million-volt x-rays. In an anesthetized cat, typical values were 90 milliliters per minute per 100 grams of tissue, with 55 percent wash-out. In a specific radiotherapy patient, the value was 65 milliliters per minute per 100 grams of tissue, with 63 percent wash-out of oxygen-15 through incorporation into tissue water.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hughes, W L -- Nussbaum, G H -- Connolly, R -- Emami, B -- Reilly, P -- New York, N.Y. -- Science. 1979 Jun 15;204(4398):1215-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451567" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Brain/*blood supply ; Cats ; Humans ; Neoplasms/blood supply ; Oxygen/*blood/radiation effects ; Oxygen Radioisotopes ; *Regional Blood Flow ; X-Rays
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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