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  • 1
    Publication Date: 2011-08-17
    Keywords: ASTROPHYSICS
    Type: Astrophysical Letters; 19; 3, 19; 1978
    Format: text
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  • 2
    ISSN: 0306-042X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The preparation of a series of N-nitrosamines for carcinogenicity studies presented an opportunity to study mass spectral fragmentation schemes in detail. Condensed spectra are listed for 146 N-nitrosamines of widely differing structures, including nitroso derivatives of commercial drugs and insecticides. Aliphatic nitrosamines were generally characterized by molecular ions and loss of OH. Subsequent fragmentation via α-cleavage is similar to that of aliphatic amines. The loss of OH is believed to result in a cyclic ion. Substituted aliphatic nitrosamines varied in fragmentation schemes with structure and position of the substituent groups. However, most showed α-cleavage at some point in fragmentation. When substituted with aromatic groups, prominent peaks due to the aromatic moiety were observed. The alicyclic nitrosamines showed losses of NO, NOH and OH and subsequent α-cleavages. Nitrosamides were characterized by rupture of the carbonyl to nitrogen bond. Spectra of substituted ureas usually showed charge retention by the carbonyl fragment, while carbamate esters showed ions from both fragments.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 444 (1978), S. 21-29 
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Chemical Reactions in Molten Salts. XVIII. Synthesis of Methyltin Trichloride, Ch3SnCl3A process for the synthesis of CH3SnCl3 by reaction of molten SnCl2 and CH2Cl infused salts is described. Out of the systems investigated with NaCl, KCl, AlCl3, ZnCl2, KZnCl3, LiAlCl4, NaAlCl4, KAlCl4, and CuAlCl4, the systems with NaAlCl4 and NaAlCl4/KAlCl4 proved best. We measured the space-time-yield (RZA) as a function of the salts admixed to SnCl2 as well as a function of the reaction temperatur, gasification, and inlet rate of CH3Cl respectively. The optimum reaction conditions are investigated and the system SnCl2//NaAlCl4 is described.
    Notes: Ein Verfahren zur Synthese von CH3SnCl3 durch Reaktion von geschmolzenem SnCl2 mit CH3Cl in Salzschmelzen wird beschrieben. Von den untersuchten Systemen mit NaCl, KCl, AlCl3, ZnCl2, KZnCl3, LiAlCl4, NaAlCl4, KAlCl4 und CuAlCl4 erwiesen sich als besonders vorteilhaft NaAlCl4 und NaAlCl4/KAlCl4. Gemessen wurde die Abhängigkeit der Raum-Zeit-Ausbeute (RZA) vom Zusatz von Fremdsalz zum SnCl2 sowie von der Reaktions-Temperatur, der Begasung und der Einleitgeschwindigkeit von CH3Cl, und die optimalen Versuchsbedingungen bestimmt. Das System SnCl2/NaAlCl4 wird beschrieben.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 4
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1978-03-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Conner, W E -- Masters, W M -- New York, N.Y. -- Science. 1978 Mar 3;199(4332):1004.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/622578" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal ; Behavioral Sciences/*instrumentation ; *Infrared Rays ; Silicon ; *Videotape Recording
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1978-12-08
    Description: The relative frequency of appearance of discontinuities in the postsynaptic thickening, or perforations in the subsynaptic plate, increased with age and experience. Rats reared from weaning in complex or social environments had a significantly higher proportion of occipital cortical synapses with perforations than did rats reared in isolation. In addition, the relative frequency of these perforations more than tripled between 10 and 60 days of age. Shifts in the frequency of perforations can occur independently of changes in the size of synpases. This result suggests a new potential mechanism of synaptic plasticity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Greenough, W T -- West, R W -- DeVoogd, T J -- New York, N.Y. -- Science. 1978 Dec 8;202(4372):1096-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/715459" target="_blank"〉PubMed〈/a〉
    Keywords: *Aging ; Animals ; Cerebral Cortex/ultrastructure ; Environment ; Male ; Occipital Lobe/*ultrastructure ; Rats ; Synapses/ultrastructure ; Synaptic Membranes/*ultrastructure
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 1978-06-30
    Description: A single injection of 5 or 10 microliters of ferrous or ferric chloride into rat or cat sensorimotor cortex resulted in chronic recurrent focal paroxysmal electroencephalographic discharges as well as behavioral convulsions and electrical seizures. Recurrent focal epileptiform discharge caused by cortical injection of iron salts suggests that the development of human posttraumatic epilepsy may depend, in part, on the neurochemical alterations induced by the principal metallic ions found in whole blood.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Willmore, L J -- Sypert, G W -- Munson, J V -- Hurd, R W -- New York, N.Y. -- Science. 1978 Jun 30;200(4349):1501-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/96527" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cats ; Cerebral Cortex/*drug effects/physiopathology ; *Disease Models, Animal ; Electrophysiology ; Epilepsies, Partial/*chemically induced ; Ferric Compounds ; Ferrous Compounds ; *Iron ; Rats ; Seizures/*chemically induced/physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1978-09-22
    Description: Purified mast cells secreted histamine when fused to phospholipid vesicles containing calcium but not magnesium or potassium. Microscopic observation revealed highly localized exocytotic responses involving punctate extrusion of individual granules. Calcium delivered from the vesicles to the cytoplasm is apparently a sufficient stimulus to initiate exocytosis. The results support the calcium hypothesis of stimulus-secretion coupling.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Theoharides, T C -- Douglas, W W -- New York, N.Y. -- Science. 1978 Sep 22;201(4361):1143-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/684435" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Ascitic Fluid/cytology ; Calcium/*pharmacology ; Exocytosis ; In Vitro Techniques ; Liposomes/*pharmacology ; Mast Cells/cytology/drug effects/*secretion ; Rats ; Ruthenium Red
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
    Publication Date: 1978-07-07
    Description: Cats were classically conditioned after the baroreceptor reflexes were abolished by bilateral placement of electrolytic lesions in the nucleus tractus solitarii. The conditioned increases in arterial pressure were more than five times larger than the responses obtained in similarly trained controls. This finding suggests that the baroreceptor reflexes actively inhibit conditioned increases of arterial pressure.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nathan, M A -- Tucker, L W -- Serverini, W H -- Reis, D J -- New York, N.Y. -- Science. 1978 Jul 7;201(4350):71-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/663640" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Blood Pressure ; Cats ; Conditioning, Classical/physiology ; Disease Models, Animal ; Female ; Heart Rate ; Hypertension/physiopathology ; Male ; Medulla Oblongata/*physiology ; Pressoreceptors/*physiology ; Reflex/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1978-11-17
    Description: When the septal area in young adult rats is denervated by a lesion of the fimbria-fornix, adrenergic fibers proliferate within the denervated area. The same operation performed on aged animals gives rise to a qualitatively similar but quantitatively less pronounced response. This reduction in reactive growth may reflect a decreased capacity of the aged brain to remodel its circuitry and restore lost function.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Scheff, S W -- Bernardo, L S -- Cotman, C W -- New York, N.Y. -- Science. 1978 Nov 17;202(4369):775-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/715443" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenergic Fibers/cytology/*growth & development ; *Aging ; Animals ; Cell Differentiation ; Hippocampus/cytology ; Male ; Rats ; Septal Nuclei/cytology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
    Publication Date: 1978-02-17
    Description: Piglets were weaned when 1 day old and thus were denied further access to the antibodies supplied by their dam's milk. They were placed in a nursery in which contamination by the ubiquitous rotavirus steadily increased with continuous use causing a progressive increase in the incidence of vomiting, diarrhea, and death among the piglets. A similar syndrome involving an antigenically related rotavirus and analogous management practices occurs in human infants.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lecce, J G -- King, M W -- Dorsey, W E -- New York, N.Y. -- Science. 1978 Feb 17;199(4330):776-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/203032" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Newborn/immunology ; Antibody Formation ; Child, Preschool ; Colostrum/immunology ; Diarrhea/immunology/microbiology/*veterinary ; Diarrhea, Infantile/immunology ; Humans ; Infant ; Rotavirus/immunology ; Swine ; Virus Diseases/immunology/microbiology/*veterinary ; Weaning
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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