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  • Engineering  (20)
  • Life Sciences  (12)
  • Molecular Cell Biology  (12)
  • Wiley-Blackwell  (32)
  • Annual Reviews
  • Springer
  • 1980-1984
  • 1975-1979  (32)
  • 1950-1954
  • 1978  (32)
Collection
Keywords
Publisher
  • Wiley-Blackwell  (32)
  • Annual Reviews
  • Springer
Years
  • 1980-1984
  • 1975-1979  (32)
  • 1950-1954
Year
  • 1
    Electronic Resource
    Electronic Resource
    Solution of non-linear differential equations by discrete least squares (1978)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 12 (1978), S. 597-612 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A general-purpose technique has been developed for solving non-linear partial differential equations. A set of approximating functions with undetermined parameters is used to evaluate the differential equation and boundary conditions at discrete points, forming a set of residuals to be minimized. The parameters which minimize the sum of squared residuals are determined by a non-linear least-squares minimization technique. Initial value problems are solved by integrating the equations with respect to time at the fitting points by a predictor-corrector algorithm. The resulting formulation is independent of the form of the problem and the approximating functions, so that a broad class of problems may be solved with a single computer program. The technique is applied to several boundary and initial value problems in one and two spatial dimensions. The tecnique is applied to several boundary and initial value problems in one and two spatial dimensions.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620120405
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  • 2
    Electronic Resource
    Electronic Resource
    Glycolipids as indicators of tumorigenesis (1978)
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 9 (1978), S. 157-177 
    Details
    ISSN: 0091-7419
    Keywords: hyperplastic liver nodules ; hepatoma ; N-2-fluorenylacetamide ; ganglioside ; sialic acid ; carcinogenesis ; cancer detection ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Hyperplastic liver nodules and hepatocellular carcinomas were induced in rats by oral administration of the carcinogen N-2-fluorenylacetamide. Neoplastic tissue was compared with control, fetal, neonatal, and precancerous liver tissues. The development of the tumors was slow, such that temporal changes in the biochemical and morphologic development of carcinogenesis could be identified. Ganglioside sialic acid levels were elevated in all but the most poorly differentiated tumors. Experiments to monitor individual enzymes suggested that the alterations in glycolipid composition were a direct effect of alterations in biosynthetic activities. The pattern during tumorigenesis was the inverse of that during normal development. Also, ganglioside patterns showed a progressive simplification from hyperplastic nodules to well-differentiated hepatomas and through two grades of poorly differentiated hepatomas. An increase in the activity of the branchpoint enzyme of ganglioside biosynthesis preceded both a decrease in the branchpoint enzyme of the disialoganglioside pathway and a marked increase in the galactosyltransferase of GM1 formation. The results indicate that ganglioside deletions are the end result of a cascade of events in the tumorigenic transformation. The onset of ganglioside deletions but not of the cascade per se may correlate with the onset of malignancy.Glycolipid levels are elevated early in certain surrounding tissues especially in the blood. In rats bearing transplantable hepatomas, serum levels of lipidbound sialic acid were elevated 2.5-fold. Similar results were obtained with sera of mice bearing transplantable mammary carcinomas and of cancer patients. These findings provide new emphasis for gangliosides in both cancer detection and as regulatory signals for growth and multiplication of cells.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jss.400090203
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  • 3
    Electronic Resource
    Electronic Resource
    Modification to the Suhara-Fukuda method of network generation (1978)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 12 (1978), S. 93-99 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: This note describes improvements to the Suhara-Fukuda method for generating a triangular finite element network. These are based on the use of a node generation procedure which distributes nodes is a regular pattern across the network area and is sufficiently flexible to permit any variation in element density. Because of the regular node distribution, poorly shaped elements will not arise and so the procedure for connecting the nodes to form elements can be simplified. Examples of networks generaed in this way are given.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620120110
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  • 4
    Electronic Resource
    Electronic Resource
    On least squares approximations to indefinite problems of the mixed type (1978)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 12 (1978), S. 453-469 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A least squares method is presented for computing approximate solutions of indefinite partial differential equations of the mixed type such as those that arise in connection with transonic flutter analysis. The mehod retains the advantages of finite difference schemes namely simplicity and sparsity of the resulting matrix system. However, it offers some great advantages over finite difference schemes. First, the method is insensitive to the value of the forcing frequency i.e., the resulting matrix system is always symmetric and positive definite,. As a result, iterative methods may be successfully employed to solve the matrix system, thus taking full advantage of the sparsity. Furthermore, the method is insensitive to the type of the partial differential equation, i.e., the computational algorithm is the same in elliptic and hyperbolic regions. In this work the method is formulated and numerical results for model problems are presented. Some theoretical aspects of least squares approximations are also discussed.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620120307
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  • 5
    Electronic Resource
    Electronic Resource
    A systematic procedure for generating useful conformal mappings (1978)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 12 (1978), S. 1651-1657 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A Procedure is presented for generating a class of conformal mappings useful in the formulation of finite-difference problems involving curved boundaries. The method provides a systematic approach that is capable, in principle, of reducing the geometry to a nearly-rectangular domain for a wide variety of partical problems. The introduction of sheared co-ordinates in this computational domain then provides for solution of the problem in a nearly-orthogonal (in fact, nearly-conformal) co-ordinate system, with its boundaries corresponding to co-ordinate lines. The method is based upon the Schwarz-Christoffel transformation and is quite simple to apply. Several examples illustrating the types of geometries which can be treated in this manner are presented.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620121103
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  • 6
    Electronic Resource
    Electronic Resource
    Thin plate semiloof element for structural analysis-including stability and natural vibrations (1978)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 12 (1978), S. 1667-1676 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: This paper presents a thin plate element formulated along parallel lines to the general three-dimensional Semiloof shell element. This plate version possesses only one half of the total number of degrees-of-freedom of the shell element and has the advantqage that the formulation of the strains and other terms is very much simplified. The element is first assessed in static situations and then its performance in the solution of eigenvalue problems is considered.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620121105
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  • 7
    Electronic Resource
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    The visco-plastic approach to problems of plasticity and creep involving geometric non-linear effects (1978)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 12 (1978), S. 169-181 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The visco-plastic model is used in the context of large displacement (geometrically non-linear) analysis. As the process now involves in numerical computation an updating of relevant stiffness matrices, formulation which is stable and computtionally more efficient. The applications shown demonstrate the applicability of the process to large displacement elasto-plastic shell analysis as well as to problems of creep buckling.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620120116
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  • 8
    Electronic Resource
    Electronic Resource
    Hydrodynamic confficients of some heaving cylinders of arbitrary shape (1978)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 13 (1978), S. 17-33 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The fluid forces acting on a uniform cylinder with an infinitely long axis, heaving in the free surface or an infinite ideal fluid, are described in terms of its ‘added mass’ and ‘damping coefficient’. The techniques of multipole expansion and multiparameter conformal transformation are adopted for such calculations and applied to shapes which cannot be adequately represented by the conventional, and more rudimentary, ‘Lewis form fit’. The shapes referred to are both relevant to ship bows, one being a ‘fine section’ and the other a ‘bulbous section’. The parameters which influence the accuracy of the solution are examined. Results for these two sections are computed and compared with results based on (a) the ‘Lewis form approximation’ and (b) the ‘Frank's close fit method’ which employs a singularity representation.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620130103
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  • 9
    Electronic Resource
    Electronic Resource
    Acoustic radiation and scattering from elastic structures (1978)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 13 (1978), S. 123-138 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: This paper presents a numerical technique for the linear dynamic analysis of a finite elastic structure immersed in an infinite homogeneous acoustic medium. It is required to determine the vibrational motion of the structure and also the associated acoustic field in the fluid, when the structure is either subjected to internal applied forces or is acting as a scatterer of an incident acoustic wave. A finite element analysis of the structure is matched at the structure-fluid interface with an integral equation representation of the exterior acoustic field, leading to a coupled system of equations which may be cast in either acoustic or structural from. The former approach is preferred here for which numerical results are presented when the method is applied to plane wave scattering by thick and thin elastic spherical shells.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620130109
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  • 10
    Electronic Resource
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    Acoustic vibration of a liquid filled distorted circular cylindrical shell (1978)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 13 (1978), S. 151-164 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A theory is developed whereby acoustic and structural modes are coupled by means of geometrical distortions in a circular cylindrical shell filled with liqued.The prediction is that a circularly symmetric discrete frequency acoustic wave in the liquid will excite in the shell not only a circular symmetric ‘breathing mode’ (which would be the only one present in an undistorted shell) but also short wavelength flexural waves at the excitation frequency. It is possible, even for quite small distortions, for the displacement amplitude of some of these flexural waves to exceed that of the ‘breathing mode’.The results of calculations for a particular shell are shown to be consistent with experimental results.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620130111
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