ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] Fig. 1 The molecular weight of ADTN is 179 and that of DBADTN 387; thus, a dose of 50 mg per kg DBADTN is equivalent to 23 mg per kg ADTN. As lipid-soluble drugs rapidly pass the blood-brain barrier, we synthesised a 'prodrug' from ADTN. A prodrug is a derivative that has certain desirable ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/276405a0
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