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  • Articles  (8)
  • Other Sources
  • Genes  (8)
  • 2010-2014
  • 1975-1979  (8)
  • 1979  (5)
  • 1978  (3)
  • Natural Sciences in General  (8)
  • Sociology
  • 1
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    Hv(1), a variable-region genetic marker of human immunoglobulin heavy chains (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-04-21
    Description: A new antigenic determinant was discovered with a hemagglutination-inhibition assay system. Designated Hv(1), it is located in the variable region of human immunoglobulin heavy chains of the G, M, and A classes. Pedigree and population analyses suggest that it has an autosomal dominant mode of inheritance. This represents the first description of an allotypic determinant in the variable region of human immunoglobulins.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wang, A C -- Mathur, S -- Pandey, J -- Siegel, F P -- Middaugh, C R -- Litman, G W -- New York, N.Y. -- Science. 1978 Apr 21;200(4339):327-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/416494" target="_blank"〉PubMed〈/a〉
    Keywords: *Binding Sites, Antibody ; Genes ; Hemagglutination Inhibition Tests ; Humans ; Immunoglobulin Fab Fragments/genetics ; Immunoglobulin Fc Fragments/genetics ; Immunoglobulin Heavy Chains/*genetics ; *Immunoglobulin Variable Region ; Pedigree
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Expression of the Escherichia coli cell division gene sep cloned in a lambda Charon phage (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-12
    Description: The Escherichia coli cell division gene sep, which probably codes for one of the penicillin-binding proteins, has been cloned into lambda Charon 10 to form a viable sep+ transducing phage. After infection with this hybrid phage, penicillin-binding protein 3 was overproduced and incorporated into the E. coli inner membrane.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Irwin, C A -- Fletcher, G -- Sills, C L -- Walker, J R -- New York, N.Y. -- Science. 1979 Oct 12;206(4415):220-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/158216" target="_blank"〉PubMed〈/a〉
    Keywords: Bacterial Proteins/genetics ; Bacteriophage lambda/genetics ; Carrier Proteins/genetics ; Cell Division ; DNA, Recombinant ; Escherichia coli/*genetics ; Genes ; Membrane Proteins/genetics ; Transduction, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Frog perspective on the morphological difference between humans and chimpanzees (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-04-14
    Description: The body shapes of humans and chimpanzees were compared quantitatively by criteria chosen for their capacity to discriminate well among the body shapes of frogs. By these criteria, the difference in body shape between humans and chimpanzees was found to be greater than that between the most dissimilar pairs of frogs examined--that is, frogs classified in separate taxonomic suborders. Even though the morphological diffference between the two primates is large by frog standards, the biochemical differences between the structural genes of these two species are small. The results of this study give quantitative support to the proposal that morphological evolution and biochemical evolution in structural genes can proceed at independent rates.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cherty, L M -- Case, S M -- Wilson, A C -- New York, N.Y. -- Science. 1978 Apr 14;200(4338):209-11.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/635583" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anthropometry ; Anura/*anatomy & histology ; *Biological Evolution ; Biometry ; Genes ; Humans ; Pan troglodytes/*anatomy & histology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    Genetic basis of XX male syndrome and XX true hermaphroditism: evidence in the dog (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-08-18
    Description: Serological analysis of white blood cells from the members of a family of American cocker spaniels indicates that a form of abnormal sexual development, in which individuals with a female karyotype have testes or ovotestes, is caused by anomalous transmission of male-determining H-Y genes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Selden, J R -- Wachtel, S S -- Koo, G C -- Haskins, M E -- Patterson, D F -- New York, N.Y. -- Science. 1978 Aug 18;201(4356):644-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/675252" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Differentiation ; Disorders of Sex Development/immunology/*veterinary ; Dog Diseases/*genetics ; Dogs ; Female ; Genes ; Genetic Linkage ; Histocompatibility Antigens/*genetics ; Leukocytes/immunology ; Male ; Ovary/growth & development ; Testis/growth & development ; Y Chromosome/immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    BK virus DNA: complete nucleotide sequence of a human tumor virus (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-10-26
    Description: The complete DNA sequence of the human papovavirus BK is presented. From the 4963 base-pair sequence of BK virus (MM strain), the amino acid sequence of at least five proteins can be deduced: a T antigen and a t antigen, which share amino terminal peptides; proteins VP2 and VP3, which share 232 amino acids; and protein VP1, whose coding sequence overlaps those for VP2 and VP3 by 113 nucleotides but is read in a different frame. The gene loci and the arrangement of genes are strikingly similar in BK virus and simian virus 40 (SV40). The sequence of the deduced proteins in BK virus shares 73 percent amino acid homology with those in SV40, whereas the DNA sequence of the two viruses shares 70 percent homology, suggesting close evolutionary relationship. However, the repeated DNA sequences in the noncoding regions of these viruses are different.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yang, R C -- Wu, R -- New York, N.Y. -- Science. 1979 Oct 26;206(4417):456-62.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/228391" target="_blank"〉PubMed〈/a〉
    Keywords: Antigens, Viral/genetics ; BK Virus/*genetics ; Base Sequence ; Codon ; DNA, Viral/*genetics ; Genes ; Genes, Regulator ; Polyomavirus/*genetics ; Simian virus 40/genetics ; Viral Proteins/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    Gene exchange and natural selection cause Bacillus subtilis to evolve in soil culture (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-11
    Description: Strains of Bacillus subtilis exchange linked blocks of genes when growing together in soil; such exchange leads to extensive reorganization of the genotypic structure of the population and to the appearance and eventual dominance of a single phenotype. This process illustrates how recombination and selection lead to adaptive changes in populations.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Graham, J P -- Istock, C A -- New York, N.Y. -- Science. 1979 May 11;204(4393):637-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/107592" target="_blank"〉PubMed〈/a〉
    Keywords: Bacillus subtilis/*genetics ; Biological Evolution ; DNA, Bacterial/*genetics ; Genes ; Genetic Variation ; Phenotype ; Recombination, Genetic ; *Soil Microbiology ; Transduction, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    A regulatory locus for mouse beta-glucuronidase induction, Gur, controls messenger RNA activity (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-02-09
    Description: A regulatory locus in a higher organism has been shown to control a specific messenger RNA activity. The Gur locus in mice regulates the production of kidney beta-glucuronidase messenger RNA activity after induction of the beta-glucuronidase structural gene, Gus, by testosterone. beta-Glucuronidase messenger RNA was assayed by its ability to direct the synthesis of catalytically active murine beta-glucuronidase in Xenopus oocytes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Paigen, K -- Labarca, C -- Watson, G -- New York, N.Y. -- Science. 1979 Feb 9;203(4380):554-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/760204" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Enzyme Induction/drug effects ; Female ; Genes ; *Genes, Regulator ; Genetic Linkage ; Glucuronidase/*genetics ; Hot Temperature ; Kidney/*enzymology ; Mice ; Oocytes/metabolism ; RNA, Messenger/*genetics ; Testosterone/pharmacology ; Xenopus
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    Linkage of loci controlling alloantigens on red blood cells and lymphocytes in the horse (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-06-22
    Description: A system of equine lymphocyte alloantigens designated ELA, is identified, and it is shown that the locus or loci controlling these markers must be closely linked to the locus controlling markers in the A system of horse blood groups. Among 29 offspring in two stallion families there was evidence for one recombinant. Lod scores for linkage between the A and ELA loci in the two families were 3.61 and 3.33, respectively, for theta equal to 0.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bailey, E -- Stormont, C -- Suzuki, Y -- Trommershausen Smith, A -- New York, N.Y. -- Science. 1979 Jun 22;204(4399):1317-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451540" target="_blank"〉PubMed〈/a〉
    Keywords: Alleles ; Animals ; Antigens, Surface/*genetics ; Blood Group Antigens/*genetics ; Erythrocyte Membrane/*immunology ; Erythrocytes/*immunology ; Genes ; Genetic Linkage ; Horses/genetics/*immunology ; Lymphocytes/*immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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