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  • AERODYNAMICS  (79)
  • Analytical Chemistry and Spectroscopy  (60)
  • Humans
  • 1975-1979  (139)
  • 1977  (139)
  • 1
    Publication Date: 2019-07-13
    Description: Results of experimental investigations into turbulent boundary-layer behavior under the influence of pressure gradients and with separation are presented for transonic and supersonic flow fields. In the transonic case, an axisymmetric model was implemented consisting of an annular circular arc bump affixed to a circular cylinder aligned with the flow direction. For the supersonic separation study, an oblique shock wave impinging on the wind tunnel wall boundary layer was employed to cause separation. The mean streamwise and normal velocity components as well as the respective turbulence intensities were obtained with a two-color frequency shifted laser velocimeter.
    Keywords: AERODYNAMICS
    Type: AIAA PAPER 77-47 , Aerospace Sciences Meeting; Jan 24, 1977 - Jan 26, 1977; Los Angeles, CA
    Format: text
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  • 2
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 4 (1977), S. 255-257 
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Plasma samples from volunteers who had received an oral dose of acetanilide have been analysed by gas chromatography mass spectrometry and ultraviolet absorption techniques. The gas chromatography mass spectrometry method involved extraction of the plasma and analysis of the acetanilide using selected ion monitoring with a deuterated internal standard. In the ultraviolet method the plasma was hydrolysed with acid to convert the acetanilide to aniline, and this compound was diazotized and coupled with N-1-naphthylethylene-diamine. The absorbance of the resulting complex was read at 550 nm. Acetanilide levels in plasma determined by the selected ion monitoring method were significantly lower than those measured by spectrophotometry. Pharmacokinetic data calculated from the results obtained using these two assays are very different and illustrate the need for an accurate and specific method of analysis. The major metabolites of acetanilide are shown not to interfere with these assays and the results suggest the possible presence of a new metabolite of acetanilide.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The in vivo liver metabolism of cannabinol has been studied in the mouse and rat by combined gas chromatography and mass spectrometry. Cannabinol glucuronide was the major metabolite of cannabinol in the mouse and was accompanied by relatively large amounts of 7-hydroxycannabinol, cannabinol-7-oic acid and their corresponding glucuronide conjugates. Lower concentrations of glucuronides were found in the rat. Two series of disubstituted metabolites were found containing either a 7-hydroxyl or a 7-carboxylic acid group and a second hydroxyl group in the 1″-4″ positions of the sidechain. These were of low concentration in the mouse but higher in the rat; 1″-hydroxy metabolites were particularly abundant in the latter species. Also found in the rat livers were small amounts of sidechain monohydroxy metabolites and larger quantities of 4″,5″-bisnorcannabinol-3″-oic acid; these were absent in the mouse. The metabolites were identified using the trimethylsilyl (TMS),[2H9]TMS and methyl ester-TMS derivatives, and by reduction of acid metabolites with lithium aluminium deuteride to the corresponding alcohols.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Publication Date: 2019-06-28
    Description: Comparisons of experimental and theoretical drag characteristics for a 10-percent-thick supercritical airfoil using a new version of an advanced analysis code. Comparisons are made at near-design normal-force coefficients for Reynolds numbers from 2 to 11 million. Comments are made concerning various input parameters to the code.
    Keywords: AERODYNAMICS
    Type: NASA-TM-X-74041 , NAS 1.15:X-74041
    Format: application/pdf
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  • 5
    Publication Date: 2019-06-27
    Description: The design and usage of a pilot program using a finite difference method for calculating the pressure distributions over harmonically oscillating wings in transonic flow are discussed. The procedure used is based on separating the velocity potential into steady and unsteady parts and linearizing the resulting unsteady differential equation for small disturbances. The steady velocity potential which must be obtained from some other program, is required for input. The unsteady differential equation is linear, complex in form with spatially varying coefficients. Because sinusoidal motion is assumed, time is not a variable. The numerical solution is obtained through a finite difference formulation and a line relaxation solution method.
    Keywords: AERODYNAMICS
    Type: NASA-CR-145214
    Format: application/pdf
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  • 6
    Publication Date: 2019-06-27
    Description: An unsteady linearized formulation based on Oswatitsch-Keune's parabolic method is developed to analyze transonic flow past oscillating slender bodies. In contrast to the widely used integral transform method, it is shown that all solutions can be derived by a simpler method directly in the physical plane. By various expansion procedures, low-frequency solutions then are derived according to two clearly defined frequency ranges. Adams-Sears' iteration is employed to account for the second-order effects. Stability derivatives are compared with available theories and data. It is found that the derivatives depend more sensitively on thickness than on the reduced frequency. Finally, a critical assessment of the present method is given.
    Keywords: AERODYNAMICS
    Type: AIAA Journal; 15; July 197
    Format: text
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  • 7
    Publication Date: 2019-07-13
    Description: A Boeing 747 aircraft flew 54 passes at low level over ground-based sensors. Vortex velocities were measured by a laser-Doppler velocimeter, an array of monostatic acoustic sounders, and an array of propeller anemometers. Flow visualization of the wake was achieved using smoke and balloon tracers. Preliminary results were obtained on the initial downwash field, the time for merging of the multiple vortices, the velocity fields, vortex decay, and the effects of spoilers and differential flap settings on the dissipation and structure of vortices.
    Keywords: AERODYNAMICS
    Type: AIAA PAPER 77-9 , Aerospace Sciences Meeting; Jan 24, 1977 - Jan 26, 1977; Los Angeles, CA
    Format: text
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  • 8
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 4 (1977), S. 159-171 
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Chemical ionization mass spectrometry is used at low resolution to determine the sequences of permethylated acetyl peptides. The method has been tested with 45 peptides, between 2 and 5 residues long, including examples of all of the common amino acids except cysteine and N-terminal asparagine. The isobutane chemical ionization spectra contain three principal types of N-terminal sequence ion and one type of C-terminal sequence ion. The redundant information available from these four types of sequence ion increases the reliability of the sequence determination. In prospect, isobutane chemical ionization mass spectrometry seems to be a useful technique for peptide sequence determination, and may have advantages in some cases.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: High performance liquid chromatography and mass spectrometry were used to isolate and identify theophylline, theobromine and 1,7-dimethylxanthine (paraxanthine) in plasma of human volunteers following administration of 300 mg caffeine to methylxanthine-free volunteers. Plasma from these subjects was extracted and the dimethylxanthines were separated from each other and caffeine by high performance liquid chromatography. The effluents at the chromatographic peaks corresponding to the dimethylxanthine metabolites were collected, rechromatographed in a second system and the dried residues were subjected to mass spectrometry. By comparison of their retention times and mass spectra with those of authentic compounds, theophylline, theobromine and paraxanthine were positively identified as metabolic products of caffeine.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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