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  • Articles  (34)
  • Cell & Developmental Biology  (34)
  • Male
  • Wiley-Blackwell  (34)
  • American Association for the Advancement of Science (AAAS)
  • 1975-1979  (34)
  • 1977  (34)
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  • Articles  (34)
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  • Wiley-Blackwell  (34)
  • American Association for the Advancement of Science (AAAS)
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  • 1975-1979  (34)
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  • 1
    Electronic Resource
    Electronic Resource
    Selective lethal effect of thymidine on human and mouse tumor cellsSupported by The Stehlin Foundation for Cancer Research. (1977)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 92 (1977), S. 401-405 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Human cell lines derived from a melanoma and a colon carcinoma, and cultures of human melanocytes and intestinal epithelial cells, as well as a mouse mesenchymal non-neoplastic cell line and a malignant subline of the same have been quantitatively studied in tissue culture for their sensitivity to thymidine. All three tumor lines produced solid tumors when injected into nude thymus-deficient mice. No tumors were obtained by injecting cells of the human normal long-term cultures or of the non-neoplastic mouse line.The tumor-producing lines showed a greater sensitivity to the lethal effects of high concentrations of thymidine than their non-tumor-producing counterparts. Less than 23% of the tumor cells survived 72 hours in the presence of 1 mg/ml of thymidine, in contrast to 60% or more of the non-tumor cells.Colony formation was much more inhibited by thymidine and the differential between normal and tumor cells was even more pronounced. Tumor cells which also were treated for 72 hours with 1 mg/ml of thymidine and then plated in fresh medium formed very few colonies. If the plating efficiency of the untreated controls is considered as 100%, 4.3% or less of the treated tumor cells formed colonies, in contrast to 33% or more of the non-tumor cells.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1040920308
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  • 2
    Electronic Resource
    Electronic Resource
    Anatomy and histology of the alimentary tract of the desert millipede Orthoporus ornatus (Girard) (Diplopoda: Spirostreptidae) (1977)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 151 (1977), S. 121-130 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The alimentary tract of the desert millipede Orthoporus ornatus is essentially a straight tube consisting of a histologically distinct foregut, midgut, pylorus, hindgut, and rectum. Common to each region, but often different in regional appearance, are an outer sheath layer, longitudinal and circular muscle layers, a basement membrane, and an inner epithelial layer. Foregut and midgut lumina are lined by a cuticular intima, while a peritrophic membrane occurs in the midgut lumen.Gut structure is considered in the context of the known feeding habits and digestive efficiency of this long-lived, seasonally restricted detritivore.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051510107
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  • 3
    Electronic Resource
    Electronic Resource
    Intrinsic organization of snake medial cortex: An electron microscopic and golgi study (1977)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 152 (1977), S. 247-279 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The intrinsic organization of medial cortex in snakes, primarily of the genera Natrix and Boa, was studied using Golgi and electron microscopic techniques. The area has three distinct layers, each containing a characteristic population of neurons. Stellate cells comprise a relatively small population of neurons with their somata and dendrites restricted to layer 1, the most superficial layer. Their axons course horizontally in layer 1. Candelabra cells form the largest population of neurons in medial cortex. Their somata lie densely packed in layer 2 and are joined by specialized junctions. Ascending dendrites extend from the somata into layer 1. They consist of spine-free proximal segments and spine bearing distal segments. Descending dendrites extend from the somata into the upper half of layer 3. The proximal segments bear few spines but branch into several tapered, distal segments which have a moderate covering of spines. One or two axons originate from the descending dendrites and descend through layer 3. The axons bear collaterals in the deep half of layer 3 and eventually bifurcate in the alveus. The medial branches run into the septum; the lateral branches course through other cortical areas. The axons bear frequent varicosities within medial cortex. Periventricular cells lie in the deep half of layer 3, either singly or in clusters. Their ascending dendrites extend radially into layer 1 where they branch into distal segments which resemble those of the candelabra cells. Their descending dendrites arborize horizontally in the alveus and bear a moderate covering of spines. Ependymal cells line the ventricular surface and send radial processes through the area's depth bearing lamellate processes.
    Additional Material: 25 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051520208
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  • 4
    Electronic Resource
    Electronic Resource
    Cytoplasmic bridges within the follicular epithelium of the ovarioles of two diptera, Aedes Aegypti and Stomoxys CalcitransApproved for publication by the Director, Texas Agricultural Experiment Station, as TA 12442This paper reports the results of research only. Mention of a proprietary product in this paper does not constitute an endorsement for use by the U.S. Department of Agriculture nor does it imply registration under FIFRA as amended. (1977)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 153 (1977), S. 81-85 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The cells of the follicular epithelium of the ovarioles of the mosquito, Aedes aegypti (L.), and of the stable fly, Stomoxys calcitrans (L.), have been found to be interconnected by cytoplasmic bridges. Cytoplasmic bridges have been reported between sibling gamete cells of both male and female insects, but these bridges have not been previously reported to exist between somatic cells of insects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051530105
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  • 5
    Electronic Resource
    Electronic Resource
    Histological and histochemical studies on the nervous influence on minced muscle regeneration of triceps surae of the ratSupported in part by NIH predoctoral training grant and a grant from Muscular Dystrophy Association of America to Dr. B. M. Carlson., Reported earlier in abstract form (Mong, '75). (1977)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 151 (1977), S. 451-462 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The degree of minced rat muscle regeneration in the absence of nerve fibers was compared with that of normal regenerates between one and 270 days postoperatively. Up to around 30 days, the number of muscle fibers and their morphology were comparable in both normal innervated and denervated regenerates; both showed clear cross striations and peripherally located nuclei. Histochemically, SDH and myofibrillar ATPase (pH = 9.4) reactions were positive, but there were no typical signs of fiber types in either case of regeneration. The only consistent difference in the early period was the smaller fiber cross sectional areas in denervated regenerates than in innervated ones. Starting about 40 days, the muscle fibers in innervated regenerates became differented into different fiber types (fast-twitch-oxidative-glycolytic, FOG., fast-twitch-glycolytic, FG., slow-twitch-oxidative, SO.) but there were no such activities in denervated regenerates, although their SDH and myofibrillar ATPase reactions remained positive for a long time. Degenerating muscle fibers could no longer be identified in innervated regenerates. In the denervated regenerates, however, muscle fibers underwent atrophic or degenerative changes and were replaced by connective tissue. The complete disappearance of muscle fibers varied with individual regenerates. In some cases, it occurred about 90 days and in others, traces of muscle fibers could still be seen as late as 150 days postoperatively. Thus, nerves seem to be important primarily in the late phase of regeneration; namely, differentiation of fiber types and maintenance of the structural integrity of muscle fibers.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051510309
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  • 6
    Electronic Resource
    Electronic Resource
    Comparative study of the stomatogastric system of several decapod crustacea. I. Skeleton (1977)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 152 (1977), S. 21-53 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The skeletal structure of the stomachs of several decapod Crustacea is described in detail. The general organization of the ossicles is similar for all species and the homologies of the elements can be recognized despite large variations from group to group. The Reptantia are characterized by a complex ossicle organization while the Natantia, on the other hand, are characterized by a simple organization. The various types of ossicle organization found in the decapod stomach can be arranged in a series ranging from simple to complex. The Brachyura have the most complex ossicle system and the Penaeidea the most simplified. This graded series of complexity closely follows the evolution of the Decapoda.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051520103
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  • 7
    Electronic Resource
    Electronic Resource
    Mechanics of the syrinx in Gallus gallus. II. Electromyographic studies of Ad Libitum vocalizations (1977)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 152 (1977), S. 1-19 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Records of electrical activity in the tracheal muscles of domestic chickens were obtained for a variety of ad libitum vocalizations. Primary attention was given to an analysis of events during the most complex call, crowing.Three pairs of muscles, Mm. tracheohyoideus, tracheolateralis, and sternotrachealis, can affect the configuration of a chicken's syrinx. The firing patterns of the three muscle pairs are related to their different abilities to affect the tension of the syringeal membranes. The influence of M. tracheohyoideus is most indirect and imprecise, and its role the least clearly defined. It appears to adjust the position of the trachea so that the syrinx is isolated from unpredictable and/or undesirable consequences of nuchal position and tracheal elasticity, and also helps draw the glottis caudad, thereby deepening the pharyngeal chamber. The other two muscles interact to control the tension of the vocal membranes. M. sternotrachealis relaxes the membranes by drawing the drum of the trachea caudad, or, via the syringeal ligament, by rotating the pessulus cranioventrad, or both. M. tracheolateralis tenses the membranes and/or prevents caudal movement of the origin of M. sternotrachealis, a necessity if the syringeal ligament is to rotate the pessulus.Vocalization depends on both syringeal configuration and appropriate air flow. Hence, tracheal muscles, syrinx, air sacs, and ventilatory muscles cooperate to form a vocal system. Cooperation elicits a surprising degree of redundancy. At least one call, a high pitched wail, may be produced by two very different techniques.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051520102
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  • 8
    Electronic Resource
    Electronic Resource
    On the neurosecretory system of Dendrobaena atheca Cernosvitov (1977)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 153 (1977), S. 163-185 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Four kinds of neurosecretory cells A, B, U and C are distinguished in the central nervous system of Dendrobaena atheca Cernosvitov. A cells, which show different morphological characteristics under different physiological states and during their cyclic changes, are the most active neurosecretory cells. They form the outer layer of the cortical cell zone in the cerebral ganglion. B cells are large and medium sized and are distributed in all parts of the central nervous system. U cells are found only in the sub-pharyngeal ganglion while C cells are distributed in the sub-pharyngeal as well as in the ventral nerve cord ganglion. The number and secretory activity of C cells decrease in caudal direction. Further, Gomori-positive cells are also observed in the ganglia of the vegetative nervous system.A rudimentary neurohaemal organ, the storage zone, has been observed in the cerebral ganglion and there appears to be another neurohaemal area in the ventral nerve cord ganglion. The storage zone is formed by the terminal ends of the axons of A cells. The chrome alum haematoxylin phloxin (CHP) and aldehyde fuchsin (AF) positive substances in the form of granules are found in this area. The cerebral ganglion is richly supplied by blood capillaries. The distal end of the axons of B cells are swollen like a bulb while in some cases the axons are united to form an axonal tract. Extra-cellular material is abundant in different parts of the nervous system. In all cell types, the perinuclear zone is the first to show activity in the secretory cycle. It appears that the nucleus may be involved in the elaboration of the neurosecretory material in the cells.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051530202
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  • 9
    Electronic Resource
    Electronic Resource
    Vascularization, innervation, and ultrastructure of the endocrine cell types of stannius corpuscles in the teleost Gasterosteus aculeatus (1977)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 153 (1977), S. 225-243 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The blood circulation of the Stannius corpuscles, like that of the kidneys to which the corpuscles are attached, represents a portal system. The corpuscles receive blood from the dorsal caudal vein and from a vein coming from the hypaxial musculature. They are drained by veins which enter the caudal parts of the kidneys and therefore endocrine substances released by the corpuscles pass through the kidneys before they enter the general body circulation. The corpuscles are penetrated by sympathetic nerves coming from a small subvertebral ganglion. It is likely that these nerves innervate the muscular coat around the blood vessels. The muscular coat surrounding the renal blood vessels, the collecting tubules and part of the ureters, is innervated by nerves from the same ganglion. The secretory activity of the gland cells appears to be controlled by blood borne factors, because neither synaptic contacts with these cells, nor gap junctions among the cells, have been found in thin sections and freeze-etch replicas of the corpuscles.The corpuscles contain two cell types, both presumed to have endocrine function. Histochemical and ultrastructural data indicate that the gland cells produce glycoproteins. It is likely that the contents of the secretory granules are released by exocytosis. One cell type is structurally similar to the cells described in many other teleosts and thought to be engaged in the synthesis of a hypocalcemic hormone. The ultrastructure of the second cell type resembles cells described only in other migratory species: salmonids and eels. It may be involved in the control of monovalent ions.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051530205
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  • 10
    Electronic Resource
    Electronic Resource
    Semicircular canal radii of curvature (R) in cat, guinea pig and man (1977)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 151 (1977), S. 1-15 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The radii of curvature (R) of the horizontal (Rh), anterior (Ra) and posterior (Rp) semicircular canals were measured by a new technique (called ROTA) for cat, guinea pig and man. For each canal, data points from the ossecus canal were rotated and plotted by computer such that the plane of the sheet of computer plot corresponded to the plane best fitting that canal. The radius of each osseous canal was determined and where necessary, the radius of the are of data points was corrected for thickness of the absent tissue. For cat, guinea pig and man there are differences in R between canals within a labyrinth suggesting that if other things are equal there could be differences in the average mechanical sensitivity of the canals, which is consistent with physiological recordings from primary vestibular neurons in the cat, The Rs determined by ROTA are compared with Rs determined by conventional histological means.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051510102
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