ISSN:
1573-8256
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
,
Technology
Notes:
Conclusions 1. The principal factors to be controlled in the freezing of tissues are the depth of necrosis Ln, the depth of freezing Lf, the rate of cooling VT, and the time τn required for the cold to operate. Operation is considerably improved when temperature of the instrument Tc is reduced to that of liquid neon. Operating conditions are greatly affected by the relationship between the quantity Ln and characteristics of the freezing instrument, for example the radius r0 of the tip. 2. Satisfactory freezing conditions may be obtained as follows: For relatively small depths of necrosis (Ln/r0≤1.5), by use of a temperature Tc between −75 and 100°C. For relatively large depths (Ln/r0〈2.5–3.0), by use of temperatures at liquid nitrogen level, or lower.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00556137
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