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  • liver  (4)
  • Springer  (4)
  • American Chemical Society
  • Annual Reviews
  • 1980-1984
  • 1975-1979  (4)
  • 1978  (2)
  • 1976  (2)
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Verlag/Herausgeber
  • Springer  (4)
  • American Chemical Society
  • Annual Reviews
Erscheinungszeitraum
  • 1980-1984
  • 1975-1979  (4)
Jahr
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 677-680 
    ISSN: 1573-8221
    Schlagwort(e): carbon tetrachloride ; liver ; total, nuclear, and cytoplasmic RNA ; RNA turnover
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract The effect of systematic administration of carbon tetrachloride (CCl4) to rats on the RNA content in the liver and the intensity of incorporation of the labeled precursor (uridine-H3) into it was investigated. Comparison of the results of morphological and biochemical studies revealed two consecutive stages of the toxic process, terminating in the formation of septal fibrosis. The sharpest changes in rapid RNA turnover in the rat liver were observed during the first 3 months of action of the toxic agent. The disturbance of metabolism also was reflected in a lowered RNA level and changes in the nucleo-cytoplasmic ratio in the tissue of the affected liver.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of experimental biology and medicine 86 (1978), S. 1206-1209 
    ISSN: 1573-8221
    Schlagwort(e): immunofluorescence ; cardiolipin ; phosphatidylinositol ; liver
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract The localization of phospholipid haptens (cardiolipin and phosphatidylinositol) in frozen and paraffin sections of mouse liver fixed in acetone and in an acetone-buffer-formalin mixture was studied by the indirect fluorescent antibodies method. Antiphospholipid sera specifically stained the plasma membranes of the hepatocytes, especially the region of the membrane facing the blood sinus. Detection of phospholipid haptens in liver sections with the aid of antiphospholipid sera depends on the method of obtaining and fixing the sections. Depending on the method of immunization, two types of antiphospholipid sera are obtained; they differ in their stability, in the possibility of isolating antibodies on lipid immunosorbents from them, and in their ability to stain liver sections.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of experimental biology and medicine 81 (1976), S. 489-491 
    ISSN: 1573-8221
    Schlagwort(e): liver ; liver functions ; bromsulfthalein method ; perfusion
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract In experiments on dogs the assimilatory-excretory function of the liver was studied by means of the bromsulfthalein method in the intact animal and during perfusion of the isolated organ through the portal vein by means of an artificial circulation apparatus. Under perfusion conditions the rate of uptake of the dye was 50–60% of the value of this index in the intact animal. The rate of elimination of bromsulfthalein with the bile and the biliary plasma clearance in the intact animal were five to six times higher. The main cause of the reduction in the assimilatory-excretory function of the isolated liver is evidently hypoxia developing after denervation and removal of the organ from the body, and also during extracorporeal perfusion itself.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Bulletin of experimental biology and medicine 85 (1978), S. 668-670 
    ISSN: 1573-8221
    Schlagwort(e): electron-microscopic autoradiography ; liver ; corticosterone
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract Distribution of [3H]corticosterone in the liver cells after adrenalectomy was studied by electron-microscopic autoradiography. The deficiency of endogenous glucocorticoids led to more rapid incorporation of [3H]corticosterone into the liver cells, as shown by the appearance of tracks above the nuclei of the hepatocytes and by an increase in their number above the various cytoplasmic formations.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
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