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Optical Resolution Photoacoustic Microscopy of Ovary and Fallopian Tube (2019)

Rao, Bin ; Leng, Xiandong ; Zeng, Yifeng ; [weitere]

Springer Nature

In: Scientific Reports. 2019; 9(1): 14306. Published 2019 Oct 04. doi: 10.1038/s41598-019-50743-7.

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Publikationsdatum: 2019-10-04

Beschreibung: Ovarian cancer is the leading cause of death among gynecological cancers, but is poorly amenable to preoperative diagnosis. In this study, we investigate the feasibility of “optical biopsy,” using high-optical-resolution photoacoustic microscopy (OR-PAM) to quantify the microvasculature of ovarian and fallopian tube tissue. The technique is demonstrated using excised human ovary and fallopian tube specimens imaged immediately after surgery. Quantitative parameters are derived using Amira software. The parameters include three-dimensional vascular segment count, total volume and length, which are associated with tumor angiogenesis. Qualitative results of OR-PAM demonstrate that malignant ovarian tissue has larger and more tortuous blood vessels as well as smaller vessels of different sizes, while benign and normal ovarian tissue has smaller vessels of uniform size. Quantitative analysis shows that malignant ovaries have greater tumor vessel volume, length and number of segments, as compared with benign and normal ovaries. The vascular pattern of benign fallopian tube is different than that of benign ovarian tissue. Our initial results demonstrate the potential of OR-PAM as an imaging tool for fast assessment of ovarian tissue and fallopian tube and could avoid unnecessary surgery if the risk of the examined ovary is extremely low.

Digitale ISSN: 2045-2322

Thema: Allgemeine Naturwissenschaft

Publiziert von Springer Nature

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Management and Environment Effects on Dry Matter Yields of Three Brassica Species (1993)

Wiedenhoeft, M. Hagemann

Wiley

In: Agronomy Journal. 1993; 85(3): 549-553. Published 1993 May 01. doi: 10.2134/agronj1993.00021962008500030006x.

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Publikationsdatum: 1993-05-01

Print ISSN: 0002-1962

Digitale ISSN: 1435-0645

Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft

Publiziert von Wiley

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Environmental × Genotype Effects on Seed Dormancy and After‐Ripening in Wheat 1 (1987)

Hagemann, M. G. ; Ciha, A. J.

Wiley

In: Agronomy Journal. 1987; 79(2): 192-196. Published 1987 Mar 01. doi: 10.2134/agronj1987.00021962007900020004x.

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Publikationsdatum: 1987-03-01

Print ISSN: 0002-1962

Digitale ISSN: 1435-0645

Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft

Publiziert von Wiley

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Management and Environment Effects on Brassica Forage Quality (1994)

Wiedenhoeft, M. Hagemann ; Barton, B. A.

Wiley

In: Agronomy Journal. 1994; 86(2): 227-232. Published 1994 Mar 01. doi: 10.2134/agronj1994.00021962008600020003x.

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Publikationsdatum: 1994-03-01

Print ISSN: 0002-1962

Digitale ISSN: 1435-0645

Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft

Publiziert von Wiley

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5

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Effects of chain length, conformation and α-form packing arrangement on theoretical monoacid triglyceride β′-forms (1988)

Hagemann, J. W. ; Rothfus, J. A.

Wiley

In: Journal of the American Oil Chemists' Society. 1988; 65(4): 638-646. Published 1988 Apr 01. doi: 10.1007/bf02540694.

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Publikationsdatum: 1988-04-01

Print ISSN: 0003-021X

Digitale ISSN: 1558-9331

Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Publiziert von Wiley

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6

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Crystallographic study of tritetracosanoin (1975)

Simpson, T. D. ; Hagemann, J. W.

Wiley

In: Journal of the American Oil Chemists' Society. 1975; 52(8): 303-306. Published 1975 Aug 01. doi: 10.1007/bf02637731.

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Publikationsdatum: 1975-08-01

Print ISSN: 0003-021X

Digitale ISSN: 1558-9331

Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung

Publiziert von Wiley

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Properties of recombinant glycine decarboxylase P- and H-protein subunits from the cyanobacteriumSynechocystissp. strain PCC 6803 (2007)

Hasse, Dirk ; Mikkat, Stefan ; Thrun, Hans-Albrecht ; [weitere]

Wiley

In: FEBS Letters. 2007; 581(7): 1297-1301. Published 2007 Feb 28. doi: 10.1016/j.febslet.2007.02.037.

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Publikationsdatum: 2007-02-28

Print ISSN: 0014-5793

Digitale ISSN: 1873-3468

Thema: Biologie , Chemie und Pharmazie

Publiziert von Wiley im Namen von Federation of European Biochemical Societies.

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Does soil aging affect the N2O mitigation potential of biochar? A combined microcosm and field study (2016)

Nikolas Hagemann, Johannes Harter, Radina Kaldamukova, Ivan Guzman-Bustamante, Reiner Ruser, Simone Graeff, Andreas Kappler, Sebastian Behrens

Wiley

In: GCB Bioenergy

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Publikationsdatum: 2016-07-21

Beschreibung: The application of biochar as a soil amendment to improve soil fertility has been suggested as a tool to reduce soil-borne CO 2 and non-CO 2 greenhouse gas emissions, especially nitrous oxide (N 2 O). Both lab and field trials have demonstrated N 2 O emission reduction by biochar amendment, but the long-term effect (〉1 year) has been questioned. Here we present results of a combined microcosm and field study using a powdered beech wood biochar from slow pyrolysis. The field experiment showed that both CO 2 and N 2 O emissions were still effectively reduced by biochar in the third year after application. However, biochar did not influence the biomass yield of sunflower for biogas production ( Helianthus annuus L.). Biochar reduced bulk density and increased soil aeration and thus reduced the water filled pore space (WFPS) in the field, but was also able to suppress N 2 O emission in the microcosms experiment conducted at constant WFPS. For both experiments, biochar had limited impact on soil mineral nitrogen speciation, but it reduced the accumulation of nitrite in the microcosms. Extraction of soil DNA and quantification of functional marker genes by qPCR showed that biochar did not alter the abundance of nitrogen-transforming bacteria and archaea in both field and microcosm experiments. In contradiction to previous experiments, this study demonstrates the long-term N 2 O emission suppression potential of a wood biochar and thus highlights its overall climate change mitigation potential. While a detailed understanding of the underlying mechanisms requires further research we provide evidence for a range of biochar-induced changes to the soil environment and their change with time that might explain the often observed N 2 O emission suppression. This article is protected by copyright. All rights reserved.

Print ISSN: 1757-1693

Digitale ISSN: 1757-1707

Thema: Energietechnik

Publiziert von Wiley

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Corrigendum: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer (2016)

Khaled Ali; Dalya R. Soond; Roberto Piñeiro; Thorsten Hagemann; Wayne Pearce; Ee Lyn Lim; Hicham Bouabe; Cheryl L. Scudamore; Timothy Hancox; Heather Maecker; Lori Friedman; Martin Turner; Klaus Okkenhaug; Bart Vanhaesebroeck

Springer Nature

In: Nature

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Publikationsdatum: 2016-07-28

Beschreibung: Corrigendum: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer Nature 535, 7613 (2016). doi:10.1038/nature17641 Authors: Khaled Ali, Dalya R. Soond, Roberto Piñeiro, Thorsten Hagemann, Wayne Pearce, Ee Lyn Lim, Hicham Bouabe, Cheryl L. Scudamore, Timothy Hancox, Heather Maecker, Lori Friedman, Martin Turner, Klaus Okkenhaug & Bart Vanhaesebroeck Nature510, 407–411 (2014); doi:10.1038/nature13444Queen Mary University London notified Nature and University College London that there is reason to question the provenance of the data for Fig. 5b, d, e of this Letter (Fig. 5a, c

Print ISSN: 0028-0836

Digitale ISSN: 1476-4687

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Publiziert von Springer Nature

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Impact of soil moisture-climate feedbacks on CMIP5 projections: First results from the GLACE-CMIP5 experiment (2013)

Sonia I. Seneviratne, Micah Wilhelm, Tanja Stanelle, Bart Hurk, Stefan Hagemann, Alexis Berg, Frederique Cheruy, Matthew E. Higgins, Arndt Meier, Victor Brovkin, Martin Claussen, Agnès Ducharne, Jean-Louis Dufresne, Kirsten L. Findell, Joséfine Ghattas, David M. Lawrence, Sergey Malyshev, Markku Rummukainen, Ben Smith

Wiley

In: Geophysical Research Letters

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Publikationsdatum: 2013-09-14

Beschreibung: [1] GLACE-CMIP5 is a multi-model experiment investigating the impact of soil moisture-climate feedbacks in CMIP5 projections. We present here first GLACE-CMIP5 results based on five Earth System Models, focusing on impacts of projected changes in regional soil moisture dryness (mostly increases) on late 21 st -century climate. Projected soil moisture changes substantially impact climate in several regions in both boreal and austral summer. Strong and consistent effects are found on temperature, especially for extremes (about 1–1.5 K for mean temperature and 2–2.5 K for extreme daytime temperature). In the Northern Hemisphere, effects on mean and heavy precipitation are also found in most models, but the results are less consistent than for temperature. A direct scaling between soil moisture-induced changes in evaporative cooling and resulting changes in temperature mean and extremes is found in the simulations. In the Mediterranean region, the projected soil moisture changes affect about 25% of the projected changes in extreme temperature.

Print ISSN: 0094-8276

Digitale ISSN: 1944-8007

Thema: Geologie und Paläontologie , Physik

Publiziert von Wiley im Namen von American Geophysical Union (AGU).

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