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  • Coenzyme Q  (1)
  • Physics  (1)
  • Wiley-Blackwell  (2)
  • American Chemical Society (ACS)
  • American Institute of Physics (AIP)
  • Oxford University Press
  • 2010-2014
  • 2000-2004
  • 1980-1984
  • 1970-1974  (2)
  • 1974  (2)
Collection
Keywords
Publisher
  • Wiley-Blackwell  (2)
  • American Chemical Society (ACS)
  • American Institute of Physics (AIP)
  • Oxford University Press
Years
  • 2010-2014
  • 2000-2004
  • 1980-1984
  • 1970-1974  (2)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Mechanical properties of ultra-oriented polyethylene (1974)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Physics Edition 12 (1974), S. 635-643 
    Details
    ISSN: 0098-1273
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Semicrystalline polymers generally exhibit moduli well below their theoretical limit due to chain folding and to lack of crystal alignment. Modulus increases attainable through standard drawing procedures are limited by sample fracture before large draw ratios are reached. Using an Instron capillary rheometer which allowed a draw ratio of 〉 300, transparent polyethylene strands of unusually high c-axis orientation have been produced by a combination of pressure and shear. The virtually perfect crystalline orientation and evidence for extended chains confirm that a significant improvement in modulus can be realized by this technique. The dynamic tensile storage modulus was measured by Vibron over the temperature range -160°C to +120°C. Room-temperature moduli were 7 × 1011 dyne/cm2, higher than any reported values for drawn polyethylene. Values also remained above 1011 dyne/cm2 even at 120°C. The moduli and morphological data have been related by a model consisting of an extended-chain component in paralled with a conventional drawn morphology. Experimental and calculated moduli are compared and related to available theory.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1974.180120401
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  • 2
    Electronic Resource
    Electronic Resource
    Antimetabolites of Coenzyme Q. Their Potential Application as Antimalarials (1974)
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 13 (1974), S. 559-569 
    Details
    ISSN: 0570-0833
    Keywords: Antimetabolites ; Coenzyme Q ; Antimalarial agents ; Malaria ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Malaria is transmitted to man by the bite of the female Anopheles mosquito, man acting as the intermediate host, and the mosquito as the definitive host for the plasmodia. Plasmodia are found to have become resistant to certain chemotherapeutic agents. A new fundamental approach to malaria chemotherapy is based on the biochemical rationale of inhibition of the electron transfer mechanism in the metabolism of plasmodia by antimetabolites of coenzyme Q, which is essential for electron transfer. Coenzyme Q refers to 2,3-dimethoxy-5-methyl-1,4-benzoquinones with isoprenoid chains of varying length on C-6. In this progress report a series of synthetic antimetabolites are presented together with a discussion of their action in current pharmacological tests.
    Additional Material: 8 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/anie.197405591
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