ISSN:
0032-3888
Keywords:
Chemistry
;
Chemical Engineering
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
,
Physics
Notes:
While the body is a hostile environment for all types of polymers, an even more serious problem is that of thrombus formation induced by all foreign surfaces, including polymeric surfaces. This is a still largely unsolved problem which hinders the development of artificial internal organs. The thromboresistant materials presently proposed and used in artificial organs include heparinized surfaces and materials found to be thromboresistant in certain implantation cites. In this article tissue-polymer interactions are first discussed and then followed by a discussion of blood-polymer interactions. The mechanism of thrombus formation is presented and some of the possible interactions of blood with surfaces are suggested. Representative nonthrombogenic and thromboresistant materials are discussed.
Additional Material:
4 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/pen.760130402
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