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  • Hypothalamus  (5)
  • Springer  (5)
  • American Chemical Society
  • 2020-2023
  • 2000-2004
  • 1980-1984
  • 1975-1979  (5)
  • 1970-1974
  • 2003
  • 1978  (5)
  • 1971
Collection
Keywords
Publisher
  • Springer  (5)
  • American Chemical Society
Years
  • 2020-2023
  • 2000-2004
  • 1980-1984
  • 1975-1979  (5)
  • 1970-1974
Year
  • 1
    Electronic Resource
    Electronic Resource
    Correlative scanning-transmission electron microscopic examination of the perinatal rat brain (1978)
    Springer
    Cell & tissue research 190 (1978), S. 317-336 
    Details
    ISSN: 1432-0878
    Keywords: Third ventricle (Rat) ; Hypothalamus ; Perinatal ; Supraependymal neurons ; Median eminence ; SEM-TEM
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ultrastructural organization of the perinatal hypothalamus and the dynamics of neuronal and ependymal growth and plasticity were examined in this investigation. The brains of fetal rats 16, 17 and 18 days in utero and those of postnatal rats 1–16 days post partum were fixed with aldehyde fixatives and prepared for combined SEM/TEM analysis. By day 17 in utero the ventricular (ependymal) surfaces of the fetal thalamic wall, cerebral vesicle and rhomboid fossa were relatively well differentiated with cilia and microvilli. Type II histiocytes were the first supraependymal cell to appear upon the ventricular lumen and were evident by day 17 in utero. In contrast, the apical surfaces of tanycytes of the infundibular recess as well as those of most other circumventricular organs were poorly differentiated and unremarkable. Tanycytes of the infundibular recess exhibited a simple hexagonal mosaic pattern of apposed plasmalemmata and even by day 1 post partum few cilia or microvilli were evident. By day 5–6 post partum Type I supraependymal neurons and axonal processes began to make their appearance with some emerging from the underlying parenchyma of the median eminence. By day 16 post partum the ventricular surface of the infundibular recess was comparable with that of the adult. The Type I supraependymal neurons are remarkably similar in their ultrastructural organization with parvicellular neurosecretory neurons elsewhere in the endocrine hypothalamus. Their emergence at day 5–6 post partum suggests a possible correlation with the critical period of sexual differentiation and a potential receptor role for this cell line. On the contrary this phenomenon may simply be a developmental anomaly. Nonetheless, the mergence of such elements upon the lumen of the third cerebral ventricle underscores a remarkable degree of neuronal plasticity in the perinatal hypothalamus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00218178
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  • 2
    Electronic Resource
    Electronic Resource
    Immunoelectronmicroscopic localization of vasopressin in the rat suprachiasmatic nucleus (1978)
    Springer
    Cell & tissue research 193 (1978), S. 1-10 
    Details
    ISSN: 1432-0878
    Keywords: Hypothalamus ; Suprachiasmatic nucleus ; Supraoptic nucleus ; Vasopressin ; Immunoelectron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The classical areas for arginine-vasopressin (AVP) synthesis are the magnocellular supraoptic (SON) and paraventricular nuclei. More recently AVP was also demonstrated in neurons of the parvocellular suprachiasmatic nucleus (SCN) of the rat. This result was substantiated in the present study by means of immunoelectron microscopy, by subjecting sections to antivasopressin plasma. Conventional electron microscopy revealed dense-core vesicles in the SCN cell bodies and fibres (mean diameter 94.7±0.9 nm and 84.0±1.1 nm respectively). These vesicles were infrequent within the cell bodies and could not be accumulated by ethanol administration. Immunoelectron microscopy showed a positive reaction in the cell bodies and fibres within vesicles of 93.7±1.1 nm and 98.5±1.2 nm respectively. By comparison, the cell bodies and fibres of the SON showed immunoreactive granules of 143.0±1.8 and 147.3±1.8 nm respectively. The presence in the SCN of AVP in vesicles of different size than those in the SON suggests that synthesis of this substance is indeed occurring within the SCN cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00221596
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  • 3
    Electronic Resource
    Electronic Resource
    Immunocytochemical demonstration of somatostatin-containing neurons in the hypothalamus of the domestic mallard (1978)
    Springer
    Cell & tissue research 195 (1978), S. 183-187 
    Details
    ISSN: 1432-0878
    Keywords: Somatostatin-containing neurons ; Hypothalamus ; Median eminence ; Immunocytochemistry ; Domestic mallard
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In the hypothalamus of the adult domestic mallard, small to medium-sized perikarya are stained specifically with rabbit antiserum against cyclic somatostatin (PAP technique of Sternberger). The somatostatin-immunoreactive material is located in neurons different from those containing immunoreactive LHRH, vasotocin or mesotocin. Somatostatin-containing perikarya are observed 1) in a chain-like arrangement extending from the area of the median division of the supraoptic nucleus to the caudal end of the paraventricular nucleus; 2) as single cells in the preoptic region; and 3) as a conspicuous formation in the optic tract division of the supraoptic nucleus. In the rostral portion of the median eminence, somatostatin-immunoreactive axons penetrate into the external zone. Fine accessory fiber bundles project to the neural lobe.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00233685
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  • 4
    Electronic Resource
    Electronic Resource
    β-lipotropin in brain: Localization in hypothalamic neurons by immunoperoxidase technique (1978)
    Springer
    Cell & tissue research 186 (1978), S. 393-398 
    Details
    ISSN: 1432-0878
    Keywords: β-Lipotropin ; Hypothalamus ; Hypophysial portal capillaries ; Immunocytochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary β-Lipotropin (β-LPH) has been localized in hypothalamus and pituitary of sheep and ox by the immunoperoxidase technique. In both species β-LPH was found in perikarya of arcuate neurons as well as in cells of the anterior and intermediate lobes of the pituitary. A large number of immunoreactive axons were found in the arcuate region; some appeared to innervate other neurons and others projected to portal capillaries. Stained fiber segments were also scattered throughout the hypothalamus. The presence of β-LPH in hypothalamic neurons supports the possibility that brain β-LPH may be a precursor for opiate-like or other peptides which may be involved in neuromodulation or neurohormonal activities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224929
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  • 5
    Electronic Resource
    Electronic Resource
    Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat (1978)
    Springer
    Cell & tissue research 186 (1978), S. 423-433 
    Details
    ISSN: 1432-0878
    Keywords: Vasopressin ; Oxytocin ; Immunohistochemistry ; Hypothalamus ; Memory consolidation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Perfusion of rat brain followed by immersion fixation with 2.5% glutaraldehyde-1% paraformaldehyde, purification of the first antisera and application of the unlabelled antibody enzyme method were used to specifically identify vasopressin and oxytocin containing cells and fibres. The conventional sites of production of these hormones were confirmed as follows: supraoptic and paraventricular nuclei, suprachiasmatic nucleus (only vasopressin), and other cells and cell groups of the hypothalamus. Fibres from the suprachiasmatic nucleus spread out in various directions, and probably project to the nucleus praeopticus periventricularis, organum vasculosum laminae terminalis and in the direction of the supraoptic nucleus. Oxytocin and vasopressin containing pathways could be traced from the paraventricular nucleus to the lateral ventricle, the stria terminalis and the stria medullaris. Some of the oxytocin and vasopressin containing tracts appear to continue onto the septum. The possible importance of these morphological findings for the behavioural effects of vasopressin and oxytocin is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224932
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