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  • Articles  (496)
  • Springer  (496)
  • 2020-2023
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  • 1965-1969  (496)
  • 1969  (496)
  • Medicine  (496)
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  • Articles  (496)
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  • 2020-2023
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  • 1965-1969  (496)
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  • 1
    Electronic Resource
    Electronic Resource
    Equilibrium potentials of postsynaptic membrane activated by various cholinomimetics during changes in extracellular ionic medium (1969)
    Springer
    Neuroscience and behavioral physiology 3 (1969), S. 41-50 
    Details
    ISSN: 1573-899X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01124453
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  • 2
    Electronic Resource
    Electronic Resource
    Unit postsynaptic potentials in the cat motor cortex to stimuli of different modalities (1969)
    Springer
    Neuroscience and behavioral physiology 3 (1969), S. 89-99 
    Details
    ISSN: 1573-899X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 1. Intracellular postsynaptic potentials (PSPs) generated in 67 neurons of the anterior and posterior sigmoid gyri of the cat were investigated under chloralose anesthesia (60–80 mg/kg) in response to presentation of somesthetic, photic and acoustic stimuli. 2. In each neuron, in response to all stimuli tested, PSPs of fairly similar shape and with similar properties were recorded. 3. In most neurons the response consisted of a primary EPSP, followed by a long (100–500 msec) IPSP. The primary EPSPs had a duration of 5–50 msec and they usually led to generation of 1–10 spikes. In three cells somesthetic stimulation evoked spike discharges, while photic and acoustic stimulation evoked only subthreshold EPSPs. The IPSP effectively inhibited spontaneous activity and “injury” discharges, while if KCl electrodes were used, it was converted into a depolarizing potential. The latent periods of the responses to electrodermal stimulation of the contralateral rorelimb varied for different neurons between 9 and 32 msec (mean 18 msec), to stimulation of the ipsilateral hindlimb they varied from 13 to 30 msec (mean 22 msec), to clicks from 10 to 65 msec (mean 21 msec), and to flashes from 12 to 50 msec (mean 31 msec). A valid correlation was found between the values of the latent periods for different stimuli. 4. On passing a current through the intracellular microelectrode, regular changes were observed in the PSPs, identical for responses to all stimuli. During hyperpolarization of the membrane the EPSPs increased in amplitude, while during depolarization they decreased, and with currents of 2−4×10−9a, they changed their sign. The IPSPs behaved in the opposite manner. 5. The results obtained are regarded as confirmation of the view that primary convergence of stimuli of different modalities for the motor cortex does not occur to any great degree at the cortical neuron. It is postulated that these stimuli enter the cortex along pathways basically similar in their organization, or even along the same pathways, forming powerful synaptic connections terminating near the cell bodies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01125919
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  • 3
    Electronic Resource
    Electronic Resource
    Cytopathic action of UNA virus on BHK-21 cultures (1969)
    Springer
    Bulletin of experimental biology and medicine 68 (1969), S. 1423-1425 
    Details
    ISSN: 1573-8221
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00790315
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  • 4
    Electronic Resource
    Electronic Resource
    The effect of pinealectomy and environmental lighting on the gonadal, thyroid, and total body weight of female long-evans rats (1969)
    Springer
    Cellular and molecular life sciences 25 (1969), S. 531-532 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Die Ovarien pinealektomierter Tiere weisen bei konstanter starker Beleuchtung ein geringes Gewicht auf, während bei Tieren, die in Dunkelheit gehalten wurden, der Uterus im Vergleich zu Kontrolltieren schwerer ist.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01900805
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  • 5
    Electronic Resource
    Electronic Resource
    Transport of mast cells by the blood circulation (1969)
    Springer
    Cellular and molecular life sciences 25 (1969), S. 735-736 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Untersuchungen der Gewebemastzellen im Rattenblut ergaben eine bedeutende Zunahme der Mastzellen nach Behandlung mit Cortison. Ein Transport der Mastzellen von lymphatischen Organen über den Blutweg in die Peripherie wie auch eine lokale Umwandlung lymphoider Elemente in Mastzellen wird experimentell wahrscheinlich gemacht.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01897594
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  • 6
    Electronic Resource
    Electronic Resource
    Circadian fluctuations in tibia cartilage — Assayable pituitary homogenates of fed and starved weanling female rats (1969)
    Springer
    Cellular and molecular life sciences 25 (1969), S. 755-756 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Mit Tibiatest auf Wachstumshormonaktivität geprüftes Hypophysenmaterial zeigte trotz Fastenperioden zirkadische Gehaltsschwankungen. Die Wahrscheinlichkeit besteht, dass Wachstumshormone und eventuelle andere hypophysäre Hormone in ihrer Aktivität der «Biologischen Uhr» unterworfen sind.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01897609
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  • 7
    Electronic Resource
    Electronic Resource
    Central depressant properties of 3,1-benzoxazine derivatives (1969)
    Springer
    Cellular and molecular life sciences 25 (1969), S. 787-788 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Riassunto Sono stati studiati 13 derivati della 3,1-benzossazina, la maggior parte dei quali sono risultati attivi come anticonvulsivanti. Tra di essi il più interessante è risultato il 4H-4-dimetil-6-bromo-3,1-benzossazine-2-one (IV).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01897874
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  • 8
    Electronic Resource
    Electronic Resource
    Toxigenic fungi associated with stored corn (1969)
    Springer
    Mycopathologia 38 (1969), S. 313-326 
    Details
    ISSN: 1573-0832
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Insgesamt sind 246 Pilzisolierungen von 25 verschimmelten Getreideproben, die in Zentral-Iowa gesammelt worden sind, erhalten worden. Sowohol Wasser- wie Aether-Extrakte von allen Getreideproben zeigten eine gewisse Toxizität in Mäusen als auch in Entchen außer einer einzigen Probe. Kulturextrakte von 99 der Pilzisolierungen, die 13 Gattungen umfaßten, verursachten den Tod in einem oder in mehreren Versuchstieren. Die Mehrheit der toxischen Isolierungen gehörte den GattungenAspergillus undPenicillium an. Drei Isolierungen vonTrichothecium roseum waren hoch toxisch für Entchen und Mäuse. Die Entchen zeigten eine schlaffe Paralyse kurz nachdem sie eine orale Dosis der Auszüge dieser drei Isolierungen erhalten hatten. Tod erfolgte häufig nach der zweiten oralen Dosis innerhalb 24 Stunden. Mäuse, die eine intraperitoneale Injektion der Auszüge vonT. roseum erhielten, zeigten erst eine Lethargie und einen intermittierenden Tremor, dann eine Hyperemotivität, aufgerauhte Haarbedeckung, abdominale Atmung, Inkoordination, Dyspnoe, klonische Zuckungen und Tod gewöhnlich innerhalb 10 bis 20 Minuten.
    Notes: Abstract A total of 246 fungal isolates were obtained from 25 moldy corn samples collected in central Iowa. Either water or ether extracts of all corn samples except one exhibited some degree of toxicity in mice and/or ducklings. At least one toxigenic isolate was obtained from each corn sample. Extracts of cultures of 99 of the fungal isolates, involving 13 genera, produced death in one or more of the assay animals. The majority of the toxigenic isolates belonged to the generaAspergillus andPenicillium. Three isolates ofTrichothecium roseum were highly toxic to ducklings and mice. The ducklings exhibited a flaccid paralysis shortly after receiving an oral dose of extracts of these three isolates. Death frequently occurred following a second oral dose given 24 hr later. Mice given intraperitoneal injections of extracts ofT. roseum first exhibited lethargy and intermittent tremors, then hyperemotivity, roughening of the hair coat, abdominal respirations, incoordination, dyspnea and clonic convulsions with death occurring usually within 10 to 20 min.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02052878
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  • 9
    Electronic Resource
    Electronic Resource
    Toxigenicity of Trichothecium roseum link: Isolation and partial characterization of a toxic metabolite (1969)
    Springer
    Mycopathologia 39 (1969), S. 231-240 
    Details
    ISSN: 1573-0832
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Eine toxische Fraktion (TR-1) ist von Reiskulturextrakten eines Stammes (MC-156) desTrichothecium roseum vom verschimmelten Mais erhalten worden. Diese toxische Fraktion war ursprünglich durch Säulen- und Dünnschicht-Chromatographie gereinigt worden und sie war chromatographically rein, wie ein einziger verkohlter Fleck an einer analytischen Dünnschichtplatte bewies. Die toxische Fraktion TR-1 hat ungefähr 12.9 % Stickstoff, und eine Ethanol-lösung dieser Fraktion besaß keine Absorption in der Spanne von 210 bis 320 mµ. Das infrarote Absorptionspektrum zeigte starke Absorptionstreifen bei 1180, 1380, 1445, 1630, 1670, 2930, 2960, und 3380 cm−1; mäßige Absorptionstreifen erschienen bei 775, 1230, 1410, 151, 1540, und 2870 cm−1. Der trockene Rückstand dieser Fraktion war leicht in Ether, Chloroform, Ethanol und Methanol auflösbar. Die toxische Fraktion TR-1 scheint eine neue und verschiedene Einheit zu sein, denn diejenigen, die vomTr. roseum beschrieben worden sind.
    Notes: Abstract A toxic fraction (TR-1) was obtained from rice culture extracts of an isolate (MC-156) ofTrichothecium roseum from moldy corn. This toxic fraction was purified primarily by column and thin-layer chromatography and was chromatographically pure as evidenced by a single charred spot on an analytical thin-layer plate. The toxic fraction TR-1 possessed approximately 12.9 % nitrogen and an ethanol solution of this fraction possessed no ultraviolet absorbance in the range from 210 to 320 mµ. The infrared absorption spectrum exhibited strong absorption bands at 1180, 1380, 1445, 1630, 1670, 1730, 2930, 2960, and 3380 cm−1; moderate absorption bands occurred at 775, 1230, 1410, 1515, 1540, and 2870 cm−1. The dry residue from this fraction was readily soluble in ether, chloroform, ethanol and methanol. The toxic fraction Tr-1 appears to be a new and different toxic entity than has been described fromT. roseum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02052787
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  • 10
    Electronic Resource
    Electronic Resource
    Sex determining mechanismXY 1Y2 inArtibeus lituratus lituratus (Chiroptera-phyllostomidae) (1969)
    Springer
    Cellular and molecular life sciences 25 (1969), S. 81-83 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Resumen En el murciélagoArtibeus lituratus lituratus el nÚmero de cromosomas es de 2n=30 en la hembra y de 2n=31 en el macho. El mecanismo de determination del sexo esXX/XY 1Y2. La translocación de un autosoma alX resultó en la diferenciación del neo-Y. Son descritos los aspectos del comportamiento del trivalente sexual durante la meiosis. Estos son comparados a los que presenta la especieNoctilio leporinus (2n=34) cuyo mecanismo esXX/X Y.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01903911
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