ISSN:
1573-4927
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract The antigenic determinants of the transferrins of 23 different primate species have been compared by a radioimmune inhibition of precipitation technique. Highest degrees of cross-reactivity with antisera to human transferrin were found in the transferrin of African apes, followed by that of the Asian apes, the Old World monkeys, the New World monkeys, and finally by the Prosimians. Thus, the evolution of the antigenic determinants on the transferrin molecule is in good agreement with the taxonomic classification of these species. Similar studies were carried out for α2-macroglobulin and various immunoglobulin chains. Parallel results were obtained except for the μ heavy chain of γM macroglobulin in which gibbon, orangutan, and gorilla probably followed a divergent line of evolution from the other Hominoidea.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00491490
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