Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
The @journal of eukaryotic microbiology
12 (1965), S. 0
ISSN:
1550-7408
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
Notes:
SYNOPSIS. The incorporation of H3-uridine during the pretransition period of heat-synchronized cells of Tetrahymena pyriformis occurs in two peaks, one at 20 and the other at approximately 40 min following the end of the last synchronizing heat treatment (EH). Although Actinomycin D tends to produce substantial inhibition of both peaks it has a significant effect on cell division only if applied before or during the first peak of incorporation. It appears that the production of new RNA is required for the first synchronous division and that it is synchronized with the division process. Actinomycin D seems to increase, slightly, the degree of incorporation of H3-uridine into RNA when applied at 0 and 10 min past EH. This effect may be correlated with the positive excess delays of division which result when cells are exposed to the inhibitor at these times. A similar effect of Actinomycin on incorporation at 30 or 40 minutes past EH, however, does not appear to be associated with any strong effects of the inhibitor on division.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1550-7408.1965.tb03249.x
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