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  • Aerospace Medicine  (2)
  • 1995-1999  (2)
  • 1960-1964
  • 1945-1949
  • 1996  (2)
  • 1962
  • 1
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    Effects of Sustained Low-Level Elevations of Carbon Dioxide on Cerebral Blood Flow and Autoregulation of the Intracerebral Arteries in Humans (1996)
    In:  CASI
    Details
    Publication Date: 2019-06-28
    Description: Cerebral blood flow velocity (CBFv) was measured by insonating the middle cerebral arteries of 4 subjects using a 2 Mhz transcranial Doppler. Ambient CO2 was elevated to 0.7% for 23 days in the first study and to 1.2% for 23 days in the same subjects in the second study. By non-parametric testing CBFv was elevated significantly by +35% above pre-exposure levels during the first 1-3 days at both exposure levels after which CBFv progressively readjusted to pre-exposure levels. Despite similar CBFv responses, headache was only reported during the initial phase of exposure to 1.2% CO2. Vascular reactivity to CO2 assessed by rebreathing showed a similar pattern with the CBFv increases early in the exposures being greater than those elicited later. An increase in metabolic rate of the visual cortex was evoked by having the subjects open and close their eyes during a visual stimulus. Evoked CBFv responses measured in the posterior cerebral artery were also elevated in the first 1-3 days of both studies returning to pre-exposure levels as hypercapnia continued. Cerebral vascular autoregulation assessed by raising head pressure during 10 deg head-down tilt both during the low-level exposures and during rebreathing was unaltered. There were no changes in the retinal microcirculation during serial fundoscopy studies. The time-dependent changes in CO2 vascular reactivity might be due either to retention of bicarbonate in brain extracellular fluid or to progressive increases in ventilation, or both. Cerebral vascular autoregulation appears preserved during chronic exposure to these levels of ambient CO2.
    Keywords: Aerospace Medicine
    Type: NASA-CR-203033 , NAS 1.26:203033
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 2
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    NASA's Technology Transfer Program for the Early Detection of Breast Cancer (1996)
    In:  CASI
    Details
    Publication Date: 2019-08-28
    Description: The National Aeronautics and Space Administration (NASA) has led the development of advanced imaging sensors and image processing technologies for space science and Earth science missions. NASA considers the transfer and commercialization of such technologies a fundamental mission of the agency. Over the last two years, efforts have been focused on the application of aerospace imaging and computing to the field of diagnostic imaging, specifically to breast cancer imaging. These technology transfer efforts offer significant promise in helping in the national public health priority of the early detection of breast cancer.
    Keywords: Aerospace Medicine
    Type: 18th Annual IEEE/EMBS International Conference; Oct 31, 1996 - Nov 03, 1996; Amsterdam; Netherlands
    Format: application/pdf
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    NASA TECHNICAL REPORTS
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